orchestrated so that there are really favorable results for the environmental wellbeing and health of all living organisms that inhabit the planet.
References
1. Mishra RK, Dubey SC (2015) Fresh water availability and it’s global challenge. Watershed
management for sustainable development. Int J Eng Sci Invention Res Dev 2(6):351–407
2. Hignite C, Azarnoff DL (1977) Drugs and drug metabolites as environmental contaminants:
chlorophenoxyisobutyrate and salicylic acid in sewage water effluent. Life Sci 20(2):337–341
3. Watts CD, Crathorne B, Fielding M, Stell CP (1983) Analysis of organic micropollutants in
water. Reidal Publishing Co, Derdrecht, pp 120–131
4. Gumbi BP, Moodley B, Birungi G, Ndungu PG (2017) Detection and quantification of acidic
drug residues in South African surface water using gas chromatography-mass spectrometry.
Chemosphere 168:1042–1050
5. Meyer W, Reich M, Beier S, Behrendt J, Gulyas H, Otterpohl R (2015) Measured and predicted
environmental concentrations of carbamazepine, diclofenac, and metoprolol in small and
medium rivers in northern Germany. Environ Monit Assess 188:487
6. Ferrer-Aguirre A, Romero-González R, Martínez Vidal JL, Garrido Frenich A (2016) Simple
and quick determination of analgesics and other contaminants of emerging concern in environmental waters by on-line solid phase extraction coupled to liquid chromatography–tandem mass
spectrometry. J Chromatogr A 1446:27–33
7. Dobor J, Varga M, Zaray G (2012) Biofilm controlled sorption of selected acidic drugs on river
sediments characterized by different organic carbon content. Chemosphere 87(2):105–110
8. Lin AYC, Panchangam SC, Chen HY (2010) Implications of human pharmaceutical occurrence
in the Sindian river of Taiwan: a strategic study of risk assessment. J Environ Monitor 12
(1):261–270
9. Kunkel U, Radke M (2011) Reactive tracer test to evaluate the fate of pharmaceuticals in rivers.
Environ Sci Technol 45(15):6296–6302
10. Santos AM, Wong A, Vicentini FC, Fatibello-Filho O (2019) Simultaneous voltammetric
sensing of levodopa, piroxicam, ofloxacin and methocarbamol using a carbon paste electrode
modified with graphite oxide and β-cyclodextrin. Microchimica Acta 186(3):174
11. Nurmi TMA, Kiljunen TK, Knuutinen JS (2018) A fugacity model assessment of ibuprofen,
diclofenac, carbamazepine, and their transformation product concentrations in an aquatic
environment. Environ Sci Pollut Res Int 26(1):328–341
12. Antonic J, Heath E (2007) Determination of NSAIDs in river sediment samples. Anal Bioanal
Chem 387(4):1337–1342
13. López-Pacheco IY, Silva-Núñez A, Salinas-Salazar C, Arévalo-Gallegos A, Lizarazo-Holguin
LA, Barceló D, Iqbal HMN, Parra-Saldívar R (2019) Anthropogenic contaminants of high
concern: existence in water resources and their adverse effects. Sci Total Environ
690:1068–1088
14. Gaw S, Thomas KV, Hutchinson TH (2014) Sources, impacts and trends of pharmaceuticals in
the marine and coastal environment. Philos Trans R Soc B 369:20130572
15. Loos R, Marinov D, Sanseverino I, Napierska D, Lettieri T (2018) Review of the 1st Watch List
under the Water Framework Directive and recommendations for the 2nd Watch List, EUR
29173 EN. Publications Office of the European Union, Luxembourg, p 15
16. Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic
reviews and meta-analyses of studies that evaluate health care interventions: explanation and
elaboration. PLoS Med 6(7):e1000100
17. Nasir MA, Hashmi RI, Ahmad NS (2012) Drug utilization patterns in Rawalpindi and Islamabad, Pakistan. J Pak Med Assoc 62:426–429
Worldwide Occurrence, Detection, and Fate of Nonsteroidal Anti-inflammatory. . .
79
References
1. Mishra RK, Dubey SC (2015) Fresh water availability and it’s global challenge. Watershed
management for sustainable development. Int J Eng Sci Invention Res Dev 2(6):351–407
2. Hignite C, Azarnoff DL (1977) Drugs and drug metabolites as environmental contaminants:
chlorophenoxyisobutyrate and salicylic acid in sewage water effluent. Life Sci 20(2):337–341
3. Watts CD, Crathorne B, Fielding M, Stell CP (1983) Analysis of organic micropollutants in
water. Reidal Publishing Co, Derdrecht, pp 120–131
4. Gumbi BP, Moodley B, Birungi G, Ndungu PG (2017) Detection and quantification of acidic
drug residues in South African surface water using gas chromatography-mass spectrometry.
Chemosphere 168:1042–1050
5. Meyer W, Reich M, Beier S, Behrendt J, Gulyas H, Otterpohl R (2015) Measured and predicted
environmental concentrations of carbamazepine, diclofenac, and metoprolol in small and
medium rivers in northern Germany. Environ Monit Assess 188:487
6. Ferrer-Aguirre A, Romero-González R, Martínez Vidal JL, Garrido Frenich A (2016) Simple
and quick determination of analgesics and other contaminants of emerging concern in environmental waters by on-line solid phase extraction coupled to liquid chromatography–tandem mass
spectrometry. J Chromatogr A 1446:27–33
7. Dobor J, Varga M, Zaray G (2012) Biofilm controlled sorption of selected acidic drugs on river
sediments characterized by different organic carbon content. Chemosphere 87(2):105–110
8. Lin AYC, Panchangam SC, Chen HY (2010) Implications of human pharmaceutical occurrence
in the Sindian river of Taiwan: a strategic study of risk assessment. J Environ Monitor 12
(1):261–270
9. Kunkel U, Radke M (2011) Reactive tracer test to evaluate the fate of pharmaceuticals in rivers.
Environ Sci Technol 45(15):6296–6302
10. Santos AM, Wong A, Vicentini FC, Fatibello-Filho O (2019) Simultaneous voltammetric
sensing of levodopa, piroxicam, ofloxacin and methocarbamol using a carbon paste electrode
modified with graphite oxide and β-cyclodextrin. Microchimica Acta 186(3):174
11. Nurmi TMA, Kiljunen TK, Knuutinen JS (2018) A fugacity model assessment of ibuprofen,
diclofenac, carbamazepine, and their transformation product concentrations in an aquatic
environment. Environ Sci Pollut Res Int 26(1):328–341
12. Antonic J, Heath E (2007) Determination of NSAIDs in river sediment samples. Anal Bioanal
Chem 387(4):1337–1342
13. López-Pacheco IY, Silva-Núñez A, Salinas-Salazar C, Arévalo-Gallegos A, Lizarazo-Holguin
LA, Barceló D, Iqbal HMN, Parra-Saldívar R (2019) Anthropogenic contaminants of high
concern: existence in water resources and their adverse effects. Sci Total Environ
690:1068–1088
14. Gaw S, Thomas KV, Hutchinson TH (2014) Sources, impacts and trends of pharmaceuticals in
the marine and coastal environment. Philos Trans R Soc B 369:20130572
15. Loos R, Marinov D, Sanseverino I, Napierska D, Lettieri T (2018) Review of the 1st Watch List
under the Water Framework Directive and recommendations for the 2nd Watch List, EUR
29173 EN. Publications Office of the European Union, Luxembourg, p 15
16. Liberati A, Altman DG, Tetzlaff J et al (2009) The PRISMA statement for reporting systematic
reviews and meta-analyses of studies that evaluate health care interventions: explanation and
elaboration. PLoS Med 6(7):e1000100
17. Nasir MA, Hashmi RI, Ahmad NS (2012) Drug utilization patterns in Rawalpindi and Islamabad, Pakistan. J Pak Med Assoc 62:426–429
Worldwide Occurrence, Detection, and Fate of Nonsteroidal Anti-inflammatory. . .
79