Identification
Screening
Eligibility
Inclusion
Records retrieved in
MEDLINE/PubMed
(n = 15)
Total records
screened for eligibility
(n = 10)
Full-text articles
screened for inclusion
(n = 2)
Final studies to be
included in the review
(n = 2)
Records excluded on the basis of: title and/or
abstract; no focus on the topic at all; (n= 5)
Records excluded based on eligibility criteria:
studies lacking data on concentrations of at least
one NSAID; NSAIDs were measured in other
type(s) of water but not groundwater; spiked or
artificial samples with added NSAIDs were studied;
(n= 8)
Fig. 3 Flow chart of included studies in the systematic review of the occurrence of NSAIDS in
groundwater samples
Identification
Screening
Eligibility
Inclusion
Records retrieved in
MEDLINE/PubMed
(n = 31)
Total records
screened for eligibility
(n = 18)
Full-text articles
screened for inclusion
(n = 3)
Final studies to be
included in the review
(n = 3)
Records excluded on the basis of: title and/or
abstract; no focus on the topic at all; (n= 13)
Records excluded based on eligibility criteria:
studies lacking data on concentrations of at least
one NSAID; NSAIDs were measured in other
type(s) of water but not drinking water; spiked or
artificial samples with added NSAIDs were studied;
(n= 15)
Fig. 4 Selection of studies retrieved for the systematic review of the presence of NSAIDS in
samples of drinking water
60
L. I. Castro-Pastrana et al.