103. Nunes B, Campos JC, Gomes R, Braga MR, Ramos AS, Antunes SC, Correia AT (2015)
Ecotoxicological effects of salicylic acid in the freshwater fish Salmo trutta fario: antioxidant
mechanisms and histological alterations. Environ Sci Pollut Res 22(1):667–678
104. Guiloski IC, Ribas JLC, Piancini LDS, Dagostim AC, Cirio SM, Fávaro LF et al (2017)
Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after
subchronic exposure. Environ Toxicol Pharmacol 53:111–120
105. Nunes B, Nunes J, Soares AM, Figueira E, Freitas R (2017) Toxicological effects of paracetamol on the clam Ruditapes philippinarum: exposure vs recovery. Aquat Toxicol 192:198–206
106. Pereira BV, Matus GN, Costa MJ, Dos Santos ACA, Silva-Zacarin EC, Do Carmo JB, Nunes
B (2018) Assessment of biochemical alterations in the neotropical fish species Phalloceros
harpagos after acute and chronic exposure to the drugs paracetamol and propranolol. Environ
Sci Pollut Res 25(15):14899–14910
107. Pounds N, Maclean S, Webley M, Pascoe D, Hutchinson T (2008) Acute and chronic effects of
ibuprofen in the mollusc Planorbis carinatus (Gastropoda: Planorbidae). Ecotoxicol Environ
Saf 70(1):47–52
108. Han S, Choi K, Kim J, Ji K, Kim S, Ahn B et al (2010) Endocrine disruption and consequences
of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa. Aquat Toxicol 98(3):256–264
109. Nallani GC, Paulos PM, Constantine LA, Venables BJ, Huggett DB (2011) Bioconcentration
of ibuprofen in fathead minnow (Pimephales promelas) and channel catfish (Ictalurus
punctatus). Chemosphere 84(10):1371–1377
110. Gonzalez-Rey M, Bebianno MJ (2011) Non-steroidal anti-inflammatory drug (NSAID) ibuprofen distresses antioxidant defense system in mussel Mytilus galloprovincialis gills. Aquat
Toxicol 105(3-4):264–269
111. Matozzo V, Rova S, Marin MG (2012) The nonsteroidal anti-inflammatory drug, ibuprofen,
affects the immune parameters in the clam Ruditapes philippinarum. Mar Environ Res
79:116–121
112. Saravanan M, Devi KU, Malarvizhi A, Ramesh M (2012) Effects of Ibuprofen on hematological, biochemical and enzymological parameters of blood in an Indian major carp, Cirrhinus
mrigala. Environ Toxicol Pharmacol 34(1):14–22
113. Bartoskova M, Dobsikova R, Stancova V, Zivna D, Blahova J, Marsalek P et al (2013)
Evaluation of ibuprofen toxicity for zebrafish (Danio rerio) targeting on selected biomarkers
of oxidative stress. Neuroendocrinol Lett 34(SUPPL 2):102–108
114. Ogueji EO, Nwani CD, Iheanacho SC, Mbah CE, Okeke CO, Yaji A (2018) Acute toxicity
effects of ibuprofen on behaviour and haematological parameters of African catfish Clarias
gariepinus (Burchell, 1822). Afr J Aquat Sci 43(3):293–303
115. Mathias FT, Fockink DH, Disner GR, Prodocimo V, Ribas JLC, Ramos LP et al (2018) Effects
of low concentrations of ibuprofen on freshwater fish Rhamdia quelen. Environ Toxicol
Pharmacol 59:105–113
116. Prášková E, Živná D, Štěpánová S, Ševčíková M, Blahová J, Maršálek P et al (2012) Acute
toxicity of acetylsalicylic acid to juvenile and embryonic stages of Danio rerio.
Neuroendocrinol Lett 33:72–76
117. Zivna D, Plhalova L, Praskova E, Stepanova S, Siroka Z, Sevcikova M et al (2013) Oxidative
stress parameters in fish after subchronic exposure to acetylsalicylic acid. Neuroendocrinol
Lett 34:116–122
118. Nunes B, Verde MF, Soares AM (2015) Biochemical effects of the pharmaceutical drug
paracetamol on Anguilla anguilla. Environ Sci Pollut Res 22(15):11574–11584
119. Zivna D, Sehonova P, Plhalova L, Marsalek P, Blahova J, Prokes M et al (2015) Effect of
salicylic acid on early life stages of common carp (Cyprinus carpio). Environ Toxicol
Pharmacol 40(1):319–325
120. Stancová V, Ziková A, Svobodová Z, Kloas W (2015) Effects of the non-steroidal antiinflammatory drug (NSAID) naproxen on gene expression of antioxidant enzymes in zebrafish
(Danio rerio). Environ Toxicol Pharmacol 40(2):343–348
Introduction and Historical Findings That Focused Nonsteroidal. . .
39
Ecotoxicological effects of salicylic acid in the freshwater fish Salmo trutta fario: antioxidant
mechanisms and histological alterations. Environ Sci Pollut Res 22(1):667–678
104. Guiloski IC, Ribas JLC, Piancini LDS, Dagostim AC, Cirio SM, Fávaro LF et al (2017)
Paracetamol causes endocrine disruption and hepatotoxicity in male fish Rhamdia quelen after
subchronic exposure. Environ Toxicol Pharmacol 53:111–120
105. Nunes B, Nunes J, Soares AM, Figueira E, Freitas R (2017) Toxicological effects of paracetamol on the clam Ruditapes philippinarum: exposure vs recovery. Aquat Toxicol 192:198–206
106. Pereira BV, Matus GN, Costa MJ, Dos Santos ACA, Silva-Zacarin EC, Do Carmo JB, Nunes
B (2018) Assessment of biochemical alterations in the neotropical fish species Phalloceros
harpagos after acute and chronic exposure to the drugs paracetamol and propranolol. Environ
Sci Pollut Res 25(15):14899–14910
107. Pounds N, Maclean S, Webley M, Pascoe D, Hutchinson T (2008) Acute and chronic effects of
ibuprofen in the mollusc Planorbis carinatus (Gastropoda: Planorbidae). Ecotoxicol Environ
Saf 70(1):47–52
108. Han S, Choi K, Kim J, Ji K, Kim S, Ahn B et al (2010) Endocrine disruption and consequences
of chronic exposure to ibuprofen in Japanese medaka (Oryzias latipes) and freshwater cladocerans Daphnia magna and Moina macrocopa. Aquat Toxicol 98(3):256–264
109. Nallani GC, Paulos PM, Constantine LA, Venables BJ, Huggett DB (2011) Bioconcentration
of ibuprofen in fathead minnow (Pimephales promelas) and channel catfish (Ictalurus
punctatus). Chemosphere 84(10):1371–1377
110. Gonzalez-Rey M, Bebianno MJ (2011) Non-steroidal anti-inflammatory drug (NSAID) ibuprofen distresses antioxidant defense system in mussel Mytilus galloprovincialis gills. Aquat
Toxicol 105(3-4):264–269
111. Matozzo V, Rova S, Marin MG (2012) The nonsteroidal anti-inflammatory drug, ibuprofen,
affects the immune parameters in the clam Ruditapes philippinarum. Mar Environ Res
79:116–121
112. Saravanan M, Devi KU, Malarvizhi A, Ramesh M (2012) Effects of Ibuprofen on hematological, biochemical and enzymological parameters of blood in an Indian major carp, Cirrhinus
mrigala. Environ Toxicol Pharmacol 34(1):14–22
113. Bartoskova M, Dobsikova R, Stancova V, Zivna D, Blahova J, Marsalek P et al (2013)
Evaluation of ibuprofen toxicity for zebrafish (Danio rerio) targeting on selected biomarkers
of oxidative stress. Neuroendocrinol Lett 34(SUPPL 2):102–108
114. Ogueji EO, Nwani CD, Iheanacho SC, Mbah CE, Okeke CO, Yaji A (2018) Acute toxicity
effects of ibuprofen on behaviour and haematological parameters of African catfish Clarias
gariepinus (Burchell, 1822). Afr J Aquat Sci 43(3):293–303
115. Mathias FT, Fockink DH, Disner GR, Prodocimo V, Ribas JLC, Ramos LP et al (2018) Effects
of low concentrations of ibuprofen on freshwater fish Rhamdia quelen. Environ Toxicol
Pharmacol 59:105–113
116. Prášková E, Živná D, Štěpánová S, Ševčíková M, Blahová J, Maršálek P et al (2012) Acute
toxicity of acetylsalicylic acid to juvenile and embryonic stages of Danio rerio.
Neuroendocrinol Lett 33:72–76
117. Zivna D, Plhalova L, Praskova E, Stepanova S, Siroka Z, Sevcikova M et al (2013) Oxidative
stress parameters in fish after subchronic exposure to acetylsalicylic acid. Neuroendocrinol
Lett 34:116–122
118. Nunes B, Verde MF, Soares AM (2015) Biochemical effects of the pharmaceutical drug
paracetamol on Anguilla anguilla. Environ Sci Pollut Res 22(15):11574–11584
119. Zivna D, Sehonova P, Plhalova L, Marsalek P, Blahova J, Prokes M et al (2015) Effect of
salicylic acid on early life stages of common carp (Cyprinus carpio). Environ Toxicol
Pharmacol 40(1):319–325
120. Stancová V, Ziková A, Svobodová Z, Kloas W (2015) Effects of the non-steroidal antiinflammatory drug (NSAID) naproxen on gene expression of antioxidant enzymes in zebrafish
(Danio rerio). Environ Toxicol Pharmacol 40(2):343–348
Introduction and Historical Findings That Focused Nonsteroidal. . .
39