Table 4
(continued)
NSAIDs
Species
Concentrations
Time Results
Source
Nimesulide
Mytilus
galloprovincialis
25
μg/L
14 d
Tissue concentrations
¼ 16.72–43.72 ng/g
Accumulation of lipofuscin in tertiary lysosomes
Micronuclei frequency
"
LMS, CAT
#
Mezzelani et al.
(2016)
HIS
hepatosomatic index, SOD
superoxide dismutase, LPO
lipid peroxidation, GST
glutathione S-transferase, Hb
hemoglobin, HPC
hydroperoxide content,
PCC
protein carbonyl content, CAT
catalase, GPx
glutathione peroxidase, GR
glutathione reductase, TBARS
thiobarbituric acid-reactive substances, BAF
bioaccumulation factor, COX1
cyclooxygenase 1, COX2
cyclooxygenase 2, Ht
hematocrit, Lt
leucocrit, MHCII
major histocompatibility complex class II, LMS
lysosomal membrane stability, ChE
cholinesterase, T
testosterone, E2
estradiol, 5-HT
serotonin, DA
dopamine, EROD
ethoxyresorufin-O-deethylase, EROD
ethoxyresorufin-O-deethylase, ETS
electron transport system, GLY
glycogen, LMS
lysosomal membrane stability, THC
total hemocyte count, NR
Neutral Red,
LDH
lactate dehydrogenase, RBC
erythrocytes, PCV
pack cell volume, WBC
leukocytes, MCV
mean corpuscular volume, MCH
mean corpuscular hemoglobin,
MCHC
mean corpuscular hemoglobin concentration, BCF
bioconcentration factor, AST
aspartate aminotransaminase, ALT
alanine transaminase, CA
carbonic
anhydrase, AChE
acetylcholinesterase, PGR
population growth rate, HIS
hepatosomatic index, GSI
gonadosomatic index, MDA
malondialdehyde, Ucp-2
uncoupling protein 2, GSH
glutathione, TOSC
total oxyradical scavenging capacity, GnRH1
gonadotropin-releasing hormone 1, GnRH2
gonadotropin-releasing
hormone 2, VTG1
vitellogenin 1, CYP19B
cytochrome 19B, CYP11A
cytochrome 11A, HMGRA
hydroxymethylglutaryl CoA reductase A, HMGRA
hydroxymethylglutaryl CoA reductase B
a
Fish were fed twice every week with Astyanax
sp. submitted to intraperitoneal inoculation with diclofenac
28
G. A. Elizalde-Velázquez and L. M. Gómez-Oliván
(continued)
NSAIDs
Species
Concentrations
Time Results
Source
Nimesulide
Mytilus
galloprovincialis
25
μg/L
14 d
Tissue concentrations
¼ 16.72–43.72 ng/g
Accumulation of lipofuscin in tertiary lysosomes
Micronuclei frequency
"
LMS, CAT
#
Mezzelani et al.
(2016)
HIS
hepatosomatic index, SOD
superoxide dismutase, LPO
lipid peroxidation, GST
glutathione S-transferase, Hb
hemoglobin, HPC
hydroperoxide content,
PCC
protein carbonyl content, CAT
catalase, GPx
glutathione peroxidase, GR
glutathione reductase, TBARS
thiobarbituric acid-reactive substances, BAF
bioaccumulation factor, COX1
cyclooxygenase 1, COX2
cyclooxygenase 2, Ht
hematocrit, Lt
leucocrit, MHCII
major histocompatibility complex class II, LMS
lysosomal membrane stability, ChE
cholinesterase, T
testosterone, E2
estradiol, 5-HT
serotonin, DA
dopamine, EROD
ethoxyresorufin-O-deethylase, EROD
ethoxyresorufin-O-deethylase, ETS
electron transport system, GLY
glycogen, LMS
lysosomal membrane stability, THC
total hemocyte count, NR
Neutral Red,
LDH
lactate dehydrogenase, RBC
erythrocytes, PCV
pack cell volume, WBC
leukocytes, MCV
mean corpuscular volume, MCH
mean corpuscular hemoglobin,
MCHC
mean corpuscular hemoglobin concentration, BCF
bioconcentration factor, AST
aspartate aminotransaminase, ALT
alanine transaminase, CA
carbonic
anhydrase, AChE
acetylcholinesterase, PGR
population growth rate, HIS
hepatosomatic index, GSI
gonadosomatic index, MDA
malondialdehyde, Ucp-2
uncoupling protein 2, GSH
glutathione, TOSC
total oxyradical scavenging capacity, GnRH1
gonadotropin-releasing hormone 1, GnRH2
gonadotropin-releasing
hormone 2, VTG1
vitellogenin 1, CYP19B
cytochrome 19B, CYP11A
cytochrome 11A, HMGRA
hydroxymethylglutaryl CoA reductase A, HMGRA
hydroxymethylglutaryl CoA reductase B
a
Fish were fed twice every week with Astyanax
sp. submitted to intraperitoneal inoculation with diclofenac
28
G. A. Elizalde-Velázquez and L. M. Gómez-Oliván
