Clarias
gariepinus
0.28, 0.33, 0.38, 0.43,
0.48 mg/L
96 h
LC
50
¼ 0.38 mg/L
Abnormal behavior: regurgitation of food, hyperactive
and jerky movements, loss of equilibrium and change
of skin coloration from shining to dull ash, irregular
fin
movements increased mucus secretions and erosion of
fins
RBC, Hb, PCV
"
MCV, MCH, MCHC
#
Ogueji et al. [114]
Rhamdia quelen
0.1, 1, 10
μg/L
14 d
GST, GPx, AChE, plasma magnesium
"
WBC, CA
#
Mathias et al. [115]
Acetylsalicylic
acid
Danio rerio
550, 560, 570, 580, 590,
600 mg/L
100, 200, 300, 400, 500,
600, 700 mg/L
96 h
96 h
LC
50
¼ 567.7 mg/L
LC
50
¼ 274.6 mg/L
GST
"
Prášková et al. [116]
0.004, 0.04, 40, 120,
250 mg/L
28 d
GST, GR, CAT, GPx
"
TBARS
#
Zivna et al. [117]
Salmo trutta
fario
25, 50, 100
μg/L
28 d
In the liver: GR, GPx
"
Histopathology: in the kidney (aneurism, epithelial cell
proliferation of the primary lamellae, epithelial lifting,
necrosis of the secondary lamellae, and lamellar tip
fusion); in the liver (sinusoidal capillaries dilatation,
hemorrhagic, inflammatory cell infiltration, hepatocellular vacuolization, and focal areas of necrosis)
Nunes et al. [118]
Cyprinus carpio
0.004, 0.04, 0.4, 4, 20 mg/L 34 d
Developmental abnormalities (retarded development,
hyperpigmentation, lordosis, kyphosis, scoliosis,
intestinal damage, body weight lower)
Histopathology: alterations to the dermo-epidermal
junction, increased mucous cell numbers
TBARS
"
Zivna et al. [119]
(continued)
Introduction and Historical Findings That Focused Nonsteroidal. . .
25
gariepinus
0.28, 0.33, 0.38, 0.43,
0.48 mg/L
96 h
LC
50
¼ 0.38 mg/L
Abnormal behavior: regurgitation of food, hyperactive
and jerky movements, loss of equilibrium and change
of skin coloration from shining to dull ash, irregular
fin
movements increased mucus secretions and erosion of
fins
RBC, Hb, PCV
"
MCV, MCH, MCHC
#
Ogueji et al. [114]
Rhamdia quelen
0.1, 1, 10
μg/L
14 d
GST, GPx, AChE, plasma magnesium
"
WBC, CA
#
Mathias et al. [115]
Acetylsalicylic
acid
Danio rerio
550, 560, 570, 580, 590,
600 mg/L
100, 200, 300, 400, 500,
600, 700 mg/L
96 h
96 h
LC
50
¼ 567.7 mg/L
LC
50
¼ 274.6 mg/L
GST
"
Prášková et al. [116]
0.004, 0.04, 40, 120,
250 mg/L
28 d
GST, GR, CAT, GPx
"
TBARS
#
Zivna et al. [117]
Salmo trutta
fario
25, 50, 100
μg/L
28 d
In the liver: GR, GPx
"
Histopathology: in the kidney (aneurism, epithelial cell
proliferation of the primary lamellae, epithelial lifting,
necrosis of the secondary lamellae, and lamellar tip
fusion); in the liver (sinusoidal capillaries dilatation,
hemorrhagic, inflammatory cell infiltration, hepatocellular vacuolization, and focal areas of necrosis)
Nunes et al. [118]
Cyprinus carpio
0.004, 0.04, 0.4, 4, 20 mg/L 34 d
Developmental abnormalities (retarded development,
hyperpigmentation, lordosis, kyphosis, scoliosis,
intestinal damage, body weight lower)
Histopathology: alterations to the dermo-epidermal
junction, increased mucous cell numbers
TBARS
"
Zivna et al. [119]
(continued)
Introduction and Historical Findings That Focused Nonsteroidal. . .
25