39. Brozinski J-M et al (2013) The anti-inflammatory drugs diclofenac, naproxen and ibuprofen are
found in the bile of wild fish caught downstream of a wastewater treatment plant. Environ Sci
Technol 47(1):342–348
40. Ding T et al (2017) Biodegradation of Naproxen by freshwater algae Cymbella sp. and
Scenedesmus quadricauda and the comparative toxicity. Bioresour Technol 238:164–173
41. Li Q et al (2016) Acute toxicity and histopathological effects of naproxen in zebrafish (Danio
rerio) early life stages. Environ Sci Pollut Res 23:18832–18841
42. Ahmad MH et al (2018) Evaluation of naproxen-induced oxidative stress, hepatotoxicity and
in-vivo genotoxicity in male Wistar rats. J Pharm Anal 8(6):400–406
43. Sánchez Pérez FJ (2018) Biodegradación en la gestión de residuos. Mol Ther 29:1–3
44. Alneyadi AH, Rauf MA, Ashraf SS (2013) Oxidoreductases for the remediation of organic
pollutants in water – a critical review. Crit Rev Biotechnol 38:1–19
45. Almeida B et al (2013) Modelling the biodegradation of non-steroidal anti-inflammatory drugs
(NSAIDs) by activated sludge and a pure culture. Bioresour Technol 133:31–37
46. Murshid S, Prakash Dhakshinamoorthy G (2019) Biodegradation of sodium diclofenac and
mefenamic acid: kinetic studies, identification of metabolites and analysis of enzyme activity.
Int Biodeter Biodegr 144:1–9
47. Lu Z et al (2019) Bioremoval of non-steroidal anti-inflammatory drugs by Pseudoxanthomonas
sp. DIN-3 isolated from biological activated carbon process. Water Res 161:459–472
48. Wegrzyn A, Felis E (2018) Isolation of bacterial endophytes from Phalaris arundinacea and
their potential in diclofenac and sulfamethoxazole degradation. Pol J Microbiol 67:321–331
49. Meerburg F et al (2012) Diclofenac and 2-anilinophenylacetate degradation by combined
activity of biogenic manganese oxides and silver. Microb Biotechnol 5:388–395
50. Moreiraa IS et al (2018) Biodegradation of diclofenac by the bacterial strain Labrys
portucalensis F11. Ecotoxicol Environ Saf 152:104–113
51. Aissaoui S et al (2017) Metabolic and co-metabolic transformation of diclofenac by
Enterobacter hormaechei D15 isolated from activated sludge. Curr Microbial 74:381–388
52. Gianfreda L, Xu F, Bollag J-M (1999) Laccases: a useful group of oxidoreductive enzymes.
Biorem J 3(1):1–26
53. Blanquez P, Guieysse B (2008) Continuous biodegradation of 17-estradiol and
17-ethynylestradiol by Trametes versicolor. J Hazard Mater 150:459–462
54. Zhang Y, Geißen S-U (2012) Elimination of carbamazepine in a non-sterile fungal bioreactor.
Bioresour Technol 112:221–227
55. Margot J et al (2013) Bacterial versus fungal laccase: potential for micropollutant degradation.
AMB Express 3:1–14
56. Li Y et al (2016) High-throughput pyrosequencing analysis of bacteria relevant to cometabolic
and metabolic degradation of ibuprofen in horizontal subsurface flow constructed wetlands. Sci
Total Environ 562:604–613
57. Verlicchi P, Zambello E (2014) How efficient are constructed wetlands in removing pharmaceuticals from untreated and treated urban wastewaters? A review. Sci Total Environ
470:1281–1306
58. Xu B, Xue G, Yang X (2018) Isolation and application of an ibuprofen-degrading bacterium to
a biological aerated filter for the treatment of micro-polluted water. Front Environ Sci Eng 12:15
59. Palyzová A et al (2018) Potential of the strain Raoultella sp. KDF8 for removal of analgesics.
Folia Microbiol 63:273–282
60. Marchlewicz A, Guzik U, Wojcieszyńska D (2017) Dynamics of ibuprofen biodegradation by
Bacillus sp. B1 (2015b). Arch Environ Prot 43(2):60–64
61. Marchlewicz A et al (2017) Toxicity and biodegradation of ibuprofen by Bacillus thuringiensis
B1 (2015b). Environ Sci Pollut Res 24:7572–7584
62. Zhong Y et al (2007) Influence of growth medium on cometabolic degradation of polycyclic
aromatic hydrocarbons by Sphingomonas sp. strain PheB4. Appl Microbiol Biotechnol
75:175–186
Biological Technologies Used for the Removal of Nonsteroidal Anti-inflammatory. . .
319
found in the bile of wild fish caught downstream of a wastewater treatment plant. Environ Sci
Technol 47(1):342–348
40. Ding T et al (2017) Biodegradation of Naproxen by freshwater algae Cymbella sp. and
Scenedesmus quadricauda and the comparative toxicity. Bioresour Technol 238:164–173
41. Li Q et al (2016) Acute toxicity and histopathological effects of naproxen in zebrafish (Danio
rerio) early life stages. Environ Sci Pollut Res 23:18832–18841
42. Ahmad MH et al (2018) Evaluation of naproxen-induced oxidative stress, hepatotoxicity and
in-vivo genotoxicity in male Wistar rats. J Pharm Anal 8(6):400–406
43. Sánchez Pérez FJ (2018) Biodegradación en la gestión de residuos. Mol Ther 29:1–3
44. Alneyadi AH, Rauf MA, Ashraf SS (2013) Oxidoreductases for the remediation of organic
pollutants in water – a critical review. Crit Rev Biotechnol 38:1–19
45. Almeida B et al (2013) Modelling the biodegradation of non-steroidal anti-inflammatory drugs
(NSAIDs) by activated sludge and a pure culture. Bioresour Technol 133:31–37
46. Murshid S, Prakash Dhakshinamoorthy G (2019) Biodegradation of sodium diclofenac and
mefenamic acid: kinetic studies, identification of metabolites and analysis of enzyme activity.
Int Biodeter Biodegr 144:1–9
47. Lu Z et al (2019) Bioremoval of non-steroidal anti-inflammatory drugs by Pseudoxanthomonas
sp. DIN-3 isolated from biological activated carbon process. Water Res 161:459–472
48. Wegrzyn A, Felis E (2018) Isolation of bacterial endophytes from Phalaris arundinacea and
their potential in diclofenac and sulfamethoxazole degradation. Pol J Microbiol 67:321–331
49. Meerburg F et al (2012) Diclofenac and 2-anilinophenylacetate degradation by combined
activity of biogenic manganese oxides and silver. Microb Biotechnol 5:388–395
50. Moreiraa IS et al (2018) Biodegradation of diclofenac by the bacterial strain Labrys
portucalensis F11. Ecotoxicol Environ Saf 152:104–113
51. Aissaoui S et al (2017) Metabolic and co-metabolic transformation of diclofenac by
Enterobacter hormaechei D15 isolated from activated sludge. Curr Microbial 74:381–388
52. Gianfreda L, Xu F, Bollag J-M (1999) Laccases: a useful group of oxidoreductive enzymes.
Biorem J 3(1):1–26
53. Blanquez P, Guieysse B (2008) Continuous biodegradation of 17-estradiol and
17-ethynylestradiol by Trametes versicolor. J Hazard Mater 150:459–462
54. Zhang Y, Geißen S-U (2012) Elimination of carbamazepine in a non-sterile fungal bioreactor.
Bioresour Technol 112:221–227
55. Margot J et al (2013) Bacterial versus fungal laccase: potential for micropollutant degradation.
AMB Express 3:1–14
56. Li Y et al (2016) High-throughput pyrosequencing analysis of bacteria relevant to cometabolic
and metabolic degradation of ibuprofen in horizontal subsurface flow constructed wetlands. Sci
Total Environ 562:604–613
57. Verlicchi P, Zambello E (2014) How efficient are constructed wetlands in removing pharmaceuticals from untreated and treated urban wastewaters? A review. Sci Total Environ
470:1281–1306
58. Xu B, Xue G, Yang X (2018) Isolation and application of an ibuprofen-degrading bacterium to
a biological aerated filter for the treatment of micro-polluted water. Front Environ Sci Eng 12:15
59. Palyzová A et al (2018) Potential of the strain Raoultella sp. KDF8 for removal of analgesics.
Folia Microbiol 63:273–282
60. Marchlewicz A, Guzik U, Wojcieszyńska D (2017) Dynamics of ibuprofen biodegradation by
Bacillus sp. B1 (2015b). Arch Environ Prot 43(2):60–64
61. Marchlewicz A et al (2017) Toxicity and biodegradation of ibuprofen by Bacillus thuringiensis
B1 (2015b). Environ Sci Pollut Res 24:7572–7584
62. Zhong Y et al (2007) Influence of growth medium on cometabolic degradation of polycyclic
aromatic hydrocarbons by Sphingomonas sp. strain PheB4. Appl Microbiol Biotechnol
75:175–186
Biological Technologies Used for the Removal of Nonsteroidal Anti-inflammatory. . .
319