induced aggregation.” These assemblies gave widely applications in the fields of
biological and medical science. However, with the aim of better understanding
of “multi-charged cyclodextrin aggregation,” there still remain several tasks including (1) modifying other groups on the rim of cyclodextrin to gain more recognition
ability, (2) finding the differences among α-, β-, and γ-cyclodextrin in “molecularinduced aggregation” and taking advantage of it, and (3) extending the scope of
stimuli-responsive method. It could be expected that these endeavors will bring the
supramolecular assemblies based on multi-charged cyclodextrin aggregation more
prospect.
Acknowledgments We thank NNSFC (21432004, 21672113, 21772099, 21861132001) for financial support.
References
1. Crini G (2014) Review: a history of cyclodextrins. Chem Rev 114(21):10940–10975
2. Chen Y, Liu Y (2015) Construction and functions of cyclodextrin-based 1D supramolecular
strands and their secondary assemblies. Adv Mater 27(36):5403–5409
3. Hapiot F, Tilloy S, Monflier E (2006) Cyclodextrins as supramolecular hosts for organometallic
complexes. Chem Rev 106(3):767–781
4. Guo D-S, Liu Y (2012) Calixarene-based supramolecular polymerization in solution. Chem Soc
Rev 41(18):5907–5921
5. Guo D-S, Liu Y (2014) Supramolecular chemistry of p-sulfonatocalix[n]arenes and its biological applications. Acc Chem Res 47(7):1925–1934
6. Di Costanzo L, Geremia S, Randaccio L, Purrello R, Lauceri R, Sciotto D et al (2001)
Calixarene–porphyrin supramolecular complexes: pH-tuning of the complex stoichiometry.
Angew Chem Int Ed 40(22):4245–4247
7. Rauwald U, Scherman OA (2008) Supramolecular block copolymers with cucurbit[8]uril in
water. Angew Chem Int Ed 47(21):3950–3953
8. Huang Z, Yang L, Liu Y, Wang Z, Scherman OA, Zhang X (2014) Supramolecular polymerization promoted and controlled through self-sorting. Angew Chem Int Ed 53(21):5351–5355
9. Cao Y, Hu X-Y, Li Y, Zou X, Xiong S, Lin C et al (2014) Multistimuli-responsive supramolecular vesicles based on water-soluble pillar[6]arene and SAINT complexation for controllable
drug release. J Am Chem Soc 136(30):10762–10769
10. Yang Y-W, Sun Y-L, Song N (2014) Switchable host–guest systems on surfaces. Acc Chem Res
47(7):1950–1960
11. Zhang H, Ma X, Nguyen KT, Zhao Y (2013) Biocompatible pillararene-assembly-based carriers
for dual bioimaging. ACS Nano 7(9):7853–7863
12. Chi X, Ji X, Xia D, Huang F (2015) A dual-responsive supra-amphiphilic polypseudorotaxane
constructed from a water-soluble pillar[7]arene and an azobenzene-containing random copolymer. J Am Chem Soc 137(4):1440–1443
13. Wang Y, Ma N, Wang Z, Zhang X (2007) Photocontrolled reversible supramolecular
assemblies of an azobenzene-containing surfactant with α-cyclodextrin. Angew Chem Int Ed
46(16):2823–2826
14. Zhao D, Chen Y, Liu Y (2015) Comparative studies on molecular induced aggregation of heptaimidazoliumyl-β-cyclodextrin towards anionic surfactants. Chin Chem Lett 26(7):829–833
15. Chen Y, Liu Y (2010) Cyclodextrin-based bioactive supramolecular assemblies. Chem Soc Rev
39(2):495–505
16. Chen Y, Zhang Y-M, Liu Y (2010) Multidimensional nanoarchitectures based on cyclodextrins.
Chem Commun 46(31):5622–5633
21 Supramolecular Assembly Constructed from Multi-charged Cyclodextrin. . .
585
biological and medical science. However, with the aim of better understanding
of “multi-charged cyclodextrin aggregation,” there still remain several tasks including (1) modifying other groups on the rim of cyclodextrin to gain more recognition
ability, (2) finding the differences among α-, β-, and γ-cyclodextrin in “molecularinduced aggregation” and taking advantage of it, and (3) extending the scope of
stimuli-responsive method. It could be expected that these endeavors will bring the
supramolecular assemblies based on multi-charged cyclodextrin aggregation more
prospect.
Acknowledgments We thank NNSFC (21432004, 21672113, 21772099, 21861132001) for financial support.
References
1. Crini G (2014) Review: a history of cyclodextrins. Chem Rev 114(21):10940–10975
2. Chen Y, Liu Y (2015) Construction and functions of cyclodextrin-based 1D supramolecular
strands and their secondary assemblies. Adv Mater 27(36):5403–5409
3. Hapiot F, Tilloy S, Monflier E (2006) Cyclodextrins as supramolecular hosts for organometallic
complexes. Chem Rev 106(3):767–781
4. Guo D-S, Liu Y (2012) Calixarene-based supramolecular polymerization in solution. Chem Soc
Rev 41(18):5907–5921
5. Guo D-S, Liu Y (2014) Supramolecular chemistry of p-sulfonatocalix[n]arenes and its biological applications. Acc Chem Res 47(7):1925–1934
6. Di Costanzo L, Geremia S, Randaccio L, Purrello R, Lauceri R, Sciotto D et al (2001)
Calixarene–porphyrin supramolecular complexes: pH-tuning of the complex stoichiometry.
Angew Chem Int Ed 40(22):4245–4247
7. Rauwald U, Scherman OA (2008) Supramolecular block copolymers with cucurbit[8]uril in
water. Angew Chem Int Ed 47(21):3950–3953
8. Huang Z, Yang L, Liu Y, Wang Z, Scherman OA, Zhang X (2014) Supramolecular polymerization promoted and controlled through self-sorting. Angew Chem Int Ed 53(21):5351–5355
9. Cao Y, Hu X-Y, Li Y, Zou X, Xiong S, Lin C et al (2014) Multistimuli-responsive supramolecular vesicles based on water-soluble pillar[6]arene and SAINT complexation for controllable
drug release. J Am Chem Soc 136(30):10762–10769
10. Yang Y-W, Sun Y-L, Song N (2014) Switchable host–guest systems on surfaces. Acc Chem Res
47(7):1950–1960
11. Zhang H, Ma X, Nguyen KT, Zhao Y (2013) Biocompatible pillararene-assembly-based carriers
for dual bioimaging. ACS Nano 7(9):7853–7863
12. Chi X, Ji X, Xia D, Huang F (2015) A dual-responsive supra-amphiphilic polypseudorotaxane
constructed from a water-soluble pillar[7]arene and an azobenzene-containing random copolymer. J Am Chem Soc 137(4):1440–1443
13. Wang Y, Ma N, Wang Z, Zhang X (2007) Photocontrolled reversible supramolecular
assemblies of an azobenzene-containing surfactant with α-cyclodextrin. Angew Chem Int Ed
46(16):2823–2826
14. Zhao D, Chen Y, Liu Y (2015) Comparative studies on molecular induced aggregation of heptaimidazoliumyl-β-cyclodextrin towards anionic surfactants. Chin Chem Lett 26(7):829–833
15. Chen Y, Liu Y (2010) Cyclodextrin-based bioactive supramolecular assemblies. Chem Soc Rev
39(2):495–505
16. Chen Y, Zhang Y-M, Liu Y (2010) Multidimensional nanoarchitectures based on cyclodextrins.
Chem Commun 46(31):5622–5633
21 Supramolecular Assembly Constructed from Multi-charged Cyclodextrin. . .
585