Cyclodextrin Hybrid Inorganic
Nanocomposites for Molecular Recognition,
Selective Adsorption, and Drug Delivery
15
Wenting Liang and Shaomin Shuang
Contents
15.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425
15.2 Cyclodextrin-Functionalized Carbon Nanomaterials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . 426
15.2.1 Molecular Recognition by Electrochemical and Luminescent Sensors . . . . . . . 427
15.2.2 Carbon Materials Functionalized with Cyclodextrins as Adsorbents . . . . . . . . . 431
15.2.3 Cyclodextrin-Functionalized Carbon Materials for Drug Delivery . . . . . . . . . . . 432
15.3 Cyclodextrin-Functionalized Magnetic Nanoparticles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434
15.3.1 Molecular Identification-Detection by Electrochemical and Luminescent
Sensors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435
15.3.2 Cyclodextrin-Functionalized Magnetic Materials for Adsorption and
Separation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436
15.3.3 Cyclodextrin-Functionalized Magnetic Materials for Drug Delivery . . . . . . . . . 438
15.4 Cyclodextrin-Functionalized Semiconductor Quantum Dots . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
15.4.1 CD-Functionalized QDs as an Achiral Recognition Sensing Platforms . . . . . . 440
15.4.2 CD-Functionalized QDs as a Chiral Recognition Sensing Platform . . . . . . . . . . 441
15.5 Cyclodextrin-Functionalized Noble Metal Nanoparticles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441
15.6 Conclusions and Outlooks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444
15.1 Introduction
Supramolecular hybrid inorganic nanocomposites, as a burgeoning type of hybrid
nanomaterials, have been prepared by anchoring macrocyclic organic molecules and
supramolecules onto inorganic nanoscaffolds. Macrocyclic organic molecules, such
as crown ethers, cryptands, calixarenes, cucurbiturils, pillararenes, and cyclodextrins,
have frequently been used as building blocks for supramolecular hybrid inorganic
materials. These macrocyclic molecules anchoring onto the surface of inorganic
nanomaterials particularly act as the valid host molecules that one or more “guest”
W. Liang · S. Shuang (*)
Shanxi University, Taiyuan, China
e-mail: liangwt@sxu.edu.cn; smshuang@sxu.edu.cn
© Springer Nature Singapore Pte Ltd. 2020
Y. Liu et al. (eds.), Handbook of Macrocyclic Supramolecular Assembly,
https://doi.org/10.1007/978-981-15-2686-2_17
425
Nanocomposites for Molecular Recognition,
Selective Adsorption, and Drug Delivery
15
Wenting Liang and Shaomin Shuang
Contents
15.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 425
15.2 Cyclodextrin-Functionalized Carbon Nanomaterials . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . 426
15.2.1 Molecular Recognition by Electrochemical and Luminescent Sensors . . . . . . . 427
15.2.2 Carbon Materials Functionalized with Cyclodextrins as Adsorbents . . . . . . . . . 431
15.2.3 Cyclodextrin-Functionalized Carbon Materials for Drug Delivery . . . . . . . . . . . 432
15.3 Cyclodextrin-Functionalized Magnetic Nanoparticles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 434
15.3.1 Molecular Identification-Detection by Electrochemical and Luminescent
Sensors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 435
15.3.2 Cyclodextrin-Functionalized Magnetic Materials for Adsorption and
Separation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 436
15.3.3 Cyclodextrin-Functionalized Magnetic Materials for Drug Delivery . . . . . . . . . 438
15.4 Cyclodextrin-Functionalized Semiconductor Quantum Dots . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
15.4.1 CD-Functionalized QDs as an Achiral Recognition Sensing Platforms . . . . . . 440
15.4.2 CD-Functionalized QDs as a Chiral Recognition Sensing Platform . . . . . . . . . . 441
15.5 Cyclodextrin-Functionalized Noble Metal Nanoparticles . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 441
15.6 Conclusions and Outlooks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 443
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 444
15.1 Introduction
Supramolecular hybrid inorganic nanocomposites, as a burgeoning type of hybrid
nanomaterials, have been prepared by anchoring macrocyclic organic molecules and
supramolecules onto inorganic nanoscaffolds. Macrocyclic organic molecules, such
as crown ethers, cryptands, calixarenes, cucurbiturils, pillararenes, and cyclodextrins,
have frequently been used as building blocks for supramolecular hybrid inorganic
materials. These macrocyclic molecules anchoring onto the surface of inorganic
nanomaterials particularly act as the valid host molecules that one or more “guest”
W. Liang · S. Shuang (*)
Shanxi University, Taiyuan, China
e-mail: liangwt@sxu.edu.cn; smshuang@sxu.edu.cn
© Springer Nature Singapore Pte Ltd. 2020
Y. Liu et al. (eds.), Handbook of Macrocyclic Supramolecular Assembly,
https://doi.org/10.1007/978-981-15-2686-2_17
425