enhanced fluorescence emission of TPE moiety at 471 nm, and due to the well
overlap between the emission spectrum of TPE and the absorption spectrum of
DOX, indicating that TPE could act as a fluorescent donor for DOX, the DOX
was successfully loaded into the formed nanoparticles to form a self-imaging drug
delivery system. This dynamic FRET system exhibited some advantage in the
potential clinical therapy. When the DOX was released in the cancer cells, the energy
Fig. 23 (a) Chemical structures and cartoon representations of M, P5, P5-PEG-Biotin, and PTPE.
(b) Schematic illustration of the formation of SNPs self-assembled from the amphiphilic supramolecular brush copolymer P5-PEG-Biotin. PTPE and their use as drug delivery vehicles. (Reprinted
with permission from Ref. [40]. Copyright © 2014. Royal Society of Chemistry)
13 Pillararene-Based Supramolecular Polymer
371
overlap between the emission spectrum of TPE and the absorption spectrum of
DOX, indicating that TPE could act as a fluorescent donor for DOX, the DOX
was successfully loaded into the formed nanoparticles to form a self-imaging drug
delivery system. This dynamic FRET system exhibited some advantage in the
potential clinical therapy. When the DOX was released in the cancer cells, the energy
Fig. 23 (a) Chemical structures and cartoon representations of M, P5, P5-PEG-Biotin, and PTPE.
(b) Schematic illustration of the formation of SNPs self-assembled from the amphiphilic supramolecular brush copolymer P5-PEG-Biotin. PTPE and their use as drug delivery vehicles. (Reprinted
with permission from Ref. [40]. Copyright © 2014. Royal Society of Chemistry)
13 Pillararene-Based Supramolecular Polymer
371