20. Coleman AW, Perret F, Moussa A, Dupin M, Guo Y, Perron H (2007) Calix[n]arenes as protein
sensors. In: Schrader T (ed) Creative chemical sensor systems. Springer Berlin Heidelberg,
Berlin/Heidelberg, pp 31–88
21. Erdemir S, Kocyigit O, Karakurt S (2015) A new perylene bisimide-armed calix[4]-aza-crown
as “turn on” fluorescent sensor for Hg
2+ ion and its application to living cells. Sensors Actuators
B Chem 220:381–388
22. Oguz M, Bhatti AA, Karakurt S, Aktas M, Yilmaz M (2017) New water soluble Hg(2+)
selective fluorescent calix[4]arenes: synthesis and application in living cells imaging.
Spectrochim Acta A Mol Biomol Spectrosc 171:340–345
23. Guo D-S, Uzunova VD, Su X, Liu Y, Nau WM (2011) Operational calixarene-based fluorescent
sensing systems for choline and acetylcholine and their application to enzymatic reactions.
Chem Sci 2(9):1722–1734
24. Dsouza RN, Hennig A, Nau WM (2012) Supramolecular tandem enzyme assays. Chem Eur J
18(12):3444–3459
25. Gao J, Zheng Z, Shi L, Wu S-Q, Sun H, Guo D-S (2018) Strong binding and fluorescence
sensing of bisphosphonates by guanidinium-modified calix[5]arene. Beilstein J Org Chem
14:1840–1845
26. Zheng Z, Geng W-C, Gao J, Wang Y-Y, Sun H, Guo D-S (2018) Ultrasensitive and specific
fluorescence detection of a cancer biomarker via nanomolar binding to a guanidinium-modified
calixarene. Chem Sci 9(8):2087–2091
27. Zheng Z, Geng W-C, Gao J, Mu Y-J, Guo D-S (2018) Differential calixarene receptors
create patterns that discriminate glycosaminoglycans. Org Chem Front 5(18):2685–2691
28. Yang L, Xie X, Cai L, Ran X, Li Y, Yin T, Zhao H, Li C-P (2016) p-sulfonated calix[8]arene
functionalized graphene as a “turn on” fluorescent sensing platform for aconitine determination.
Biosens Bioelectron 82:146–154
29. Minaker SA, Daze KD, Ma MC, Hof F (2012) Antibody-free reading of the histone code using
a simple chemical sensor array. J Am Chem Soc 134(28):11674–11680
30. Beatty MA, Borges-Gonzalez J, Sinclair NJ, Pye AT, Hof F (2018) Analyte-driven disassembly
and turn-on fluorescent sensing in competitive biological media. J Am Chem Soc
140(10):3500–3504
31. Guo D-S, Yang J, Liu Y (2013) Specifically monitoring butyrylcholinesterase by supramolecular tandem assay. Chem Eur J 19(27):8755–8759
32. Stewart S, Ivy MA, Anslyn EV (2014) The use of principal component analysis and discriminant analysis in differential sensing routines. Chem Soc Rev 43(1):70–84
33. Ghale G, Nau WM (2014) Dynamically analyte-responsive macrocyclic host–fluorophore
systems. Acc Chem Res 47(7):2150–2159
34. Zadmard R, Arendt M, Schrader T (2004) Multipoint recognition of basic proteins at a
membrane model. J Am Chem Soc 126(25):7752–7753
35. Zadmard R, Schrader T (2005) Nanomolar protein sensing with embedded receptor molecules.
J Am Chem Soc 127(3):904–915
36. Kolusheva S, Zadmard R, Schrader T, Jelinek R (2006) Color fingerprinting of proteins
by calixarenes embedded in lipid/polydiacetylene vesicles. J Am Chem Soc
128(41):13592–13598
37. Aime S, Barge A, Botta M, Casnati A, Fragai M, Luchinat C, Ungaro R (2001) A calix[4]arene
gdiii complex endowed with high stability, relaxivity, and binding affinity to serum albumin.
Angew Chem Int Ed 40(24):4737–4739
38. Bryant JLH, Yordanov AT, Linnoila JJ, Brechbiel MW, Frank JA (2000) First noncovalently
bound calix[4]arene-gdiii-albumin complex. Angew Chem Int Ed 39(9):1641–1643
39. Schuhle DT, van Rijn P, Laurent S, Vander Elst L, Muller RN, Stuart MC, Schatz J, Peters JA
(2010) Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on
the outside surface; an efficient potential contrast agent for MRI. Chem Commun
46(24):4399–4401
226
J. Gao and D.-S. Guo
sensors. In: Schrader T (ed) Creative chemical sensor systems. Springer Berlin Heidelberg,
Berlin/Heidelberg, pp 31–88
21. Erdemir S, Kocyigit O, Karakurt S (2015) A new perylene bisimide-armed calix[4]-aza-crown
as “turn on” fluorescent sensor for Hg
2+ ion and its application to living cells. Sensors Actuators
B Chem 220:381–388
22. Oguz M, Bhatti AA, Karakurt S, Aktas M, Yilmaz M (2017) New water soluble Hg(2+)
selective fluorescent calix[4]arenes: synthesis and application in living cells imaging.
Spectrochim Acta A Mol Biomol Spectrosc 171:340–345
23. Guo D-S, Uzunova VD, Su X, Liu Y, Nau WM (2011) Operational calixarene-based fluorescent
sensing systems for choline and acetylcholine and their application to enzymatic reactions.
Chem Sci 2(9):1722–1734
24. Dsouza RN, Hennig A, Nau WM (2012) Supramolecular tandem enzyme assays. Chem Eur J
18(12):3444–3459
25. Gao J, Zheng Z, Shi L, Wu S-Q, Sun H, Guo D-S (2018) Strong binding and fluorescence
sensing of bisphosphonates by guanidinium-modified calix[5]arene. Beilstein J Org Chem
14:1840–1845
26. Zheng Z, Geng W-C, Gao J, Wang Y-Y, Sun H, Guo D-S (2018) Ultrasensitive and specific
fluorescence detection of a cancer biomarker via nanomolar binding to a guanidinium-modified
calixarene. Chem Sci 9(8):2087–2091
27. Zheng Z, Geng W-C, Gao J, Mu Y-J, Guo D-S (2018) Differential calixarene receptors
create patterns that discriminate glycosaminoglycans. Org Chem Front 5(18):2685–2691
28. Yang L, Xie X, Cai L, Ran X, Li Y, Yin T, Zhao H, Li C-P (2016) p-sulfonated calix[8]arene
functionalized graphene as a “turn on” fluorescent sensing platform for aconitine determination.
Biosens Bioelectron 82:146–154
29. Minaker SA, Daze KD, Ma MC, Hof F (2012) Antibody-free reading of the histone code using
a simple chemical sensor array. J Am Chem Soc 134(28):11674–11680
30. Beatty MA, Borges-Gonzalez J, Sinclair NJ, Pye AT, Hof F (2018) Analyte-driven disassembly
and turn-on fluorescent sensing in competitive biological media. J Am Chem Soc
140(10):3500–3504
31. Guo D-S, Yang J, Liu Y (2013) Specifically monitoring butyrylcholinesterase by supramolecular tandem assay. Chem Eur J 19(27):8755–8759
32. Stewart S, Ivy MA, Anslyn EV (2014) The use of principal component analysis and discriminant analysis in differential sensing routines. Chem Soc Rev 43(1):70–84
33. Ghale G, Nau WM (2014) Dynamically analyte-responsive macrocyclic host–fluorophore
systems. Acc Chem Res 47(7):2150–2159
34. Zadmard R, Arendt M, Schrader T (2004) Multipoint recognition of basic proteins at a
membrane model. J Am Chem Soc 126(25):7752–7753
35. Zadmard R, Schrader T (2005) Nanomolar protein sensing with embedded receptor molecules.
J Am Chem Soc 127(3):904–915
36. Kolusheva S, Zadmard R, Schrader T, Jelinek R (2006) Color fingerprinting of proteins
by calixarenes embedded in lipid/polydiacetylene vesicles. J Am Chem Soc
128(41):13592–13598
37. Aime S, Barge A, Botta M, Casnati A, Fragai M, Luchinat C, Ungaro R (2001) A calix[4]arene
gdiii complex endowed with high stability, relaxivity, and binding affinity to serum albumin.
Angew Chem Int Ed 40(24):4737–4739
38. Bryant JLH, Yordanov AT, Linnoila JJ, Brechbiel MW, Frank JA (2000) First noncovalently
bound calix[4]arene-gdiii-albumin complex. Angew Chem Int Ed 39(9):1641–1643
39. Schuhle DT, van Rijn P, Laurent S, Vander Elst L, Muller RN, Stuart MC, Schatz J, Peters JA
(2010) Liposomes with conjugates of a calix[4]arene and a Gd-DOTA derivative on
the outside surface; an efficient potential contrast agent for MRI. Chem Commun
46(24):4399–4401
226
J. Gao and D.-S. Guo