17
3. O 2 gas.
4. 30% w/w H 2 O 2 .
5. Halogen lamp 500 W.
6. Deionized water.
7. Methanol.
8. PTFE membrane filters with pore size of 0.2 μm.
1. Oxidized CNHs.
2. Thionyl chloride.
3. Dry tetrahydrofuran.
4. Amine (or hydroxyl)-terminated drug/biomolecule.
5. PTFE membrane filters with pore size of 0.2 μm.
1. CNH powder.
2. A high-temperature (1200 °C) furnace with gas inlet.
3. O 2 gas.
4. H 2 gas.
1. Nanomesh CNHs.
2. Drugs/biomolecules.
3. Dimethyl formamide.
4. PTFE membrane filters with pore size of 0.2 μm.
3 Methods
All experiments are carried out under inert atmosphere conditions
unless otherwise stated. Solvents, chemicals and CNHs are used as
received unless otherwise stated.
The CNHs are produced in a plastic chamber by CO 2 laser ablation of graphite in an Ar (760 Torr) atmosphere at room temperature. The inside of the chamber is evacuated, Ar gas is introduced
and flowed through it, while the gas pressure is kept constant, typically at 760 Torr. The gas flow rate is 40 L/min, which is required
to move the produced CNHs immediately from the reaction chamber to the collection filter. The graphite target rod is located in the
middle of the reaction chamber. The graphite rod is rotated around
its axis at 6 rpm, and advanced along its axis so that a fresh target
is continually exposed to the laser beam. The rod is illuminated by
the laser beam vertically at its cylinder-wall surface. All laser ablation
experiments are conducted at room temperature, although the
actual target temperature rises during the ablation. Carbonaceous
products are collected by cylindrical filters located in a pumping
2.6 Conjugation
of Drugs/Biomolecules
2.7 Nanomesh CNHs
2.8 Encapsulation
of Drugs/Biomolecules
3.1 Preparation
of CNHs
Functionalized Carbon Nanohorns
3. O 2 gas.
4. 30% w/w H 2 O 2 .
5. Halogen lamp 500 W.
6. Deionized water.
7. Methanol.
8. PTFE membrane filters with pore size of 0.2 μm.
1. Oxidized CNHs.
2. Thionyl chloride.
3. Dry tetrahydrofuran.
4. Amine (or hydroxyl)-terminated drug/biomolecule.
5. PTFE membrane filters with pore size of 0.2 μm.
1. CNH powder.
2. A high-temperature (1200 °C) furnace with gas inlet.
3. O 2 gas.
4. H 2 gas.
1. Nanomesh CNHs.
2. Drugs/biomolecules.
3. Dimethyl formamide.
4. PTFE membrane filters with pore size of 0.2 μm.
3 Methods
All experiments are carried out under inert atmosphere conditions
unless otherwise stated. Solvents, chemicals and CNHs are used as
received unless otherwise stated.
The CNHs are produced in a plastic chamber by CO 2 laser ablation of graphite in an Ar (760 Torr) atmosphere at room temperature. The inside of the chamber is evacuated, Ar gas is introduced
and flowed through it, while the gas pressure is kept constant, typically at 760 Torr. The gas flow rate is 40 L/min, which is required
to move the produced CNHs immediately from the reaction chamber to the collection filter. The graphite target rod is located in the
middle of the reaction chamber. The graphite rod is rotated around
its axis at 6 rpm, and advanced along its axis so that a fresh target
is continually exposed to the laser beam. The rod is illuminated by
the laser beam vertically at its cylinder-wall surface. All laser ablation
experiments are conducted at room temperature, although the
actual target temperature rises during the ablation. Carbonaceous
products are collected by cylindrical filters located in a pumping
2.6 Conjugation
of Drugs/Biomolecules
2.7 Nanomesh CNHs
2.8 Encapsulation
of Drugs/Biomolecules
3.1 Preparation
of CNHs
Functionalized Carbon Nanohorns