15
Fig. 1 Illustration of the three general methods for the preparation of CNH-based drug/biomolecule delivery
systems. Left: Pristine CNHs are modified with a BOC-aniline derivative via diazonium chemistry, followed by
cleavage of the BOC-protecting group and covalent coupling of the free amine terminus with carboxylic acidterminated drugs/biomolecules. Middle: Sequential oxidation of CNHs introduces carboxylic acid functionalities
Functionalized Carbon Nanohorns
Fig. 1 Illustration of the three general methods for the preparation of CNH-based drug/biomolecule delivery
systems. Left: Pristine CNHs are modified with a BOC-aniline derivative via diazonium chemistry, followed by
cleavage of the BOC-protecting group and covalent coupling of the free amine terminus with carboxylic acidterminated drugs/biomolecules. Middle: Sequential oxidation of CNHs introduces carboxylic acid functionalities
Functionalized Carbon Nanohorns