161
10. Metaxa AF, Efthimiadou EK, Boukos N,
Kordas G (2012) Polysaccharides as a source
of advanced materials: cellulose hollow microspheres for drug delivery in cancer therapy.
J Colloid Interface Sci 384(1):198–206.
https://doi.org/10.1016/j.jcis.2012.04.073
11. Metaxa A-F, Efthimiadou EK, Kordas G (2014)
Cellulose-based drug carriers for cancer therapy: cytotoxic evaluation in cancer and healthy
cells. Mater Lett 132:432–435. https://doi.
org/10.1016/j.matlet.2014.06.134
12. Metaxa AF, Efthimiadou EK, Boukos N,
Fragogeorgi EA, Loudos G, Kordas G (2014)
Hollow microspheres based on - folic acid
modified - Hydroxypropyl cellulose and synthetic multi-responsive bio-copolymer for
targeted cancer therapy: controlled release of
daunorubicin, in vitro and in vivo studies. J
Colloid Interface Sci 435C:171–181. https://
doi.org/10.1016/j.jcis.2014.08.001
13. Kean T, Thanou M (2010) Biodegradation,
biodistribution and toxicity of chitosan. Adv
Drug Deliv Rev 62(1):3–11. https://doi.
org/10.1016/j.addr.2009.09.004
14. Felt O, Buri P, Gurny R (1998) Chitosan: a
unique polysaccharide for drug delivery. Drug
Dev Ind Pharm 24(11):979–993. https://doi.
org/10.3109/03639049809089942
15. Sinha VR, Singla AK, Wadhawan S, Kaushik
R, Kumria R, Bansal K, Dhawan S (2004)
Chitosan microspheres as a potential carrier for
drugs. Int J Pharm 274(1–2):1–33. https://
doi.org/10.1016/j.ijpharm.2003.12.026
16. De Villiers MM (2009) Nanotechnology in
drug delivery. Springer, New York
17. Dhawan A, Sharma V (2010) Toxicity assessment of nanomaterials: methods and challenges.
Anal Bioanal Chem 398(2):589–605. https://
doi.org/10.1007/s00216-010-3996-x
18. Powers KW, Brown SC, Krishna VB, Wasdo SC,
Moudgil BM, Roberts SM (2006) Research
strategies for safety evaluation of nanomaterials. Part VI Characterization of nanoscale particles for toxicological evaluation. Toxicol Sci
90(2):296–303. https://doi.org/10.1093/
toxsci/kfj099
Design of Drug Delivery Systems Based on Polysaccharides
10. Metaxa AF, Efthimiadou EK, Boukos N,
Kordas G (2012) Polysaccharides as a source
of advanced materials: cellulose hollow microspheres for drug delivery in cancer therapy.
J Colloid Interface Sci 384(1):198–206.
https://doi.org/10.1016/j.jcis.2012.04.073
11. Metaxa A-F, Efthimiadou EK, Kordas G (2014)
Cellulose-based drug carriers for cancer therapy: cytotoxic evaluation in cancer and healthy
cells. Mater Lett 132:432–435. https://doi.
org/10.1016/j.matlet.2014.06.134
12. Metaxa AF, Efthimiadou EK, Boukos N,
Fragogeorgi EA, Loudos G, Kordas G (2014)
Hollow microspheres based on - folic acid
modified - Hydroxypropyl cellulose and synthetic multi-responsive bio-copolymer for
targeted cancer therapy: controlled release of
daunorubicin, in vitro and in vivo studies. J
Colloid Interface Sci 435C:171–181. https://
doi.org/10.1016/j.jcis.2014.08.001
13. Kean T, Thanou M (2010) Biodegradation,
biodistribution and toxicity of chitosan. Adv
Drug Deliv Rev 62(1):3–11. https://doi.
org/10.1016/j.addr.2009.09.004
14. Felt O, Buri P, Gurny R (1998) Chitosan: a
unique polysaccharide for drug delivery. Drug
Dev Ind Pharm 24(11):979–993. https://doi.
org/10.3109/03639049809089942
15. Sinha VR, Singla AK, Wadhawan S, Kaushik
R, Kumria R, Bansal K, Dhawan S (2004)
Chitosan microspheres as a potential carrier for
drugs. Int J Pharm 274(1–2):1–33. https://
doi.org/10.1016/j.ijpharm.2003.12.026
16. De Villiers MM (2009) Nanotechnology in
drug delivery. Springer, New York
17. Dhawan A, Sharma V (2010) Toxicity assessment of nanomaterials: methods and challenges.
Anal Bioanal Chem 398(2):589–605. https://
doi.org/10.1007/s00216-010-3996-x
18. Powers KW, Brown SC, Krishna VB, Wasdo SC,
Moudgil BM, Roberts SM (2006) Research
strategies for safety evaluation of nanomaterials. Part VI Characterization of nanoscale particles for toxicological evaluation. Toxicol Sci
90(2):296–303. https://doi.org/10.1093/
toxsci/kfj099
Design of Drug Delivery Systems Based on Polysaccharides