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microbial profile and also decipher many unidentified soil processes and mechanisms (Segata et al. 2013). Insights achieved from these metagenomic data of interlinking soil, air, and water systems are navigating the hidden mystery of associated
systems and opening a new window for research for better human well-being by
improving the process of disease identification, recognition of pathogenic contamination, industrial biotechnology (bio-prospecting, bio-remediation studies, etc.)
(Handelsman 2004; Bashir et al. 2014). With the advances in precise metagenomic
DNA isolation methodology, sequencing platforms, bioinformatics tools, and highend computation biology, metagenomics is on track to solve the many global problems related to ocean sciences (oceanic microbiome), soil ecology (Earth
microbiome goal), and human health (gut and human microbiome goal) seed microbiome (Turnbaugh et al. 2007; Tseng and Tang 2014; Gilbert et al. 2014; Berg and
Raaijmakers 2018). All the aforesaid microbiome-level knowledge and development of pan-genome and the CRISPER-CAS-mediated modification system to alter
the microbial functions have given new focus to the microbial genomics and surely
will add multipurpose benefits to human health and sustainable global development
(Zhao et al. 2018; Akinsemolu 2018; Shapiro 2017).
4.2 Metagenomics
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