3 Phycobiliproteins in Microalgae: Occurrence …
59
3.8 Conclusion
The autofluorescent, brilliantly colored PBPs have indispensable property in every
sector of life science for more than 50 year. Several properties of PBPs are still to
be discovered for useful applications. The diversity of cyanobacteria and availability
of differentially colored PBPs have to be searched out for the welfare of humans.
The biosynthetic mechanisms of PBPs in various groups of cyanobacteria are still
to be discovered. PBPs play a vital role in the development of various biotechnological, foods and pharmaceutical products including natural dyes, target specific apoptotic agent, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-oxidative
medicines, value-added products and colored fluorescence dye for human welfare.
Under the current scenario, many products are under developing stage including
photodynamic therapy, biofuel solar cell, diagnostic, and many medicines for the
treatment of various diseases. The bright future and wide commercial uses of PBPs
may open large economic growth for industry as well as availability of novel products
for human welfare.
Acknowledgements V.K. Kannaujiya is thankful to the UGC Research Startup Grant, New Delhi,
India, (30–431/2018 (BSR)) for financial assistance. The work is also partially supported by DSTINSPIRE provided to Deepak Kumar in the form of Senior Research Fellowship (DST/INSPIRE
FELLOWSHIP/2015/IF150191). Prashant R. Singh is thankful to CSIR, New Delhi, Govt. of India,
for providing the financial support in form of a fellowship (09/013(0795)/2018 EMR-I).
References
Adir, N. (2005). Elucidation of the molecular structures of components of the phycobilisome:
Reconstructing a giant. Photosynthesis Research, 85, 15–32.
Anderson, G. R., & Jordan, J. V. (1961). Boron: A non-essential growth factor for Azotobacter
chroococcum. Soil Science, 92, 113–116.
Aoki, R., Goto, T., & Fujita, Y. (2011). A heme oxygenase isoform is essential for aerobic
growth in the cyanobacterium Synechocystis sp. PCC 6803: Modes of differential operation
of two isoforms/enzymes to adapt to low oxygen environments in cyanobacteria. Plant and Cell
Physiology, 52, 1744–1756.
Apt, K. E., Metzner, S., & Grossman, A. R. (2001). The γ subunits of phycoerythrin from a red alga:
Position in phycobilisomes and sequence characterization. Journal of Phycology, 37, 64–70.
Arciero, D. M., Bryant, D. A., & Glazer, A. N. (1988). In vitro attachment of bilins to apophycocyanin I: Specific covalent adduct formation at cysteinyl residues involved in phycocyanobilin
binding in C-phycocyanin. Journal of Biological Chemistry, 263, 18343–18349.
Beale, S. I., & Cornejo, J. (1991). Biosynthesis of phycobilins. Ferredoxin-mediated reduction of
biliverdin catalyzed by extracts of Cyanidium caldarium. Journal of Biological Chemistry, 266,
22328–22332.
Belkin, S., & Boussiba, S. (1991). High internal pH conveys ammonia resistance in Spirulina
platensis. Bioresource Technology, 38, 167–169.
Benedetti, S., Benvenuti, F., Scoglio, S., & Canestrari, F. (2010). Oxygen radical absorbance capacity
of phycocyanin and phycocyanobilin from the food supplement Aphanizomenon flos-aquae.
Journal of Medicinal Food, 13, 223–227.
59
3.8 Conclusion
The autofluorescent, brilliantly colored PBPs have indispensable property in every
sector of life science for more than 50 year. Several properties of PBPs are still to
be discovered for useful applications. The diversity of cyanobacteria and availability
of differentially colored PBPs have to be searched out for the welfare of humans.
The biosynthetic mechanisms of PBPs in various groups of cyanobacteria are still
to be discovered. PBPs play a vital role in the development of various biotechnological, foods and pharmaceutical products including natural dyes, target specific apoptotic agent, anti-cancer, anti-inflammatory, anti-bacterial, anti-viral, anti-oxidative
medicines, value-added products and colored fluorescence dye for human welfare.
Under the current scenario, many products are under developing stage including
photodynamic therapy, biofuel solar cell, diagnostic, and many medicines for the
treatment of various diseases. The bright future and wide commercial uses of PBPs
may open large economic growth for industry as well as availability of novel products
for human welfare.
Acknowledgements V.K. Kannaujiya is thankful to the UGC Research Startup Grant, New Delhi,
India, (30–431/2018 (BSR)) for financial assistance. The work is also partially supported by DSTINSPIRE provided to Deepak Kumar in the form of Senior Research Fellowship (DST/INSPIRE
FELLOWSHIP/2015/IF150191). Prashant R. Singh is thankful to CSIR, New Delhi, Govt. of India,
for providing the financial support in form of a fellowship (09/013(0795)/2018 EMR-I).
References
Adir, N. (2005). Elucidation of the molecular structures of components of the phycobilisome:
Reconstructing a giant. Photosynthesis Research, 85, 15–32.
Anderson, G. R., & Jordan, J. V. (1961). Boron: A non-essential growth factor for Azotobacter
chroococcum. Soil Science, 92, 113–116.
Aoki, R., Goto, T., & Fujita, Y. (2011). A heme oxygenase isoform is essential for aerobic
growth in the cyanobacterium Synechocystis sp. PCC 6803: Modes of differential operation
of two isoforms/enzymes to adapt to low oxygen environments in cyanobacteria. Plant and Cell
Physiology, 52, 1744–1756.
Apt, K. E., Metzner, S., & Grossman, A. R. (2001). The γ subunits of phycoerythrin from a red alga:
Position in phycobilisomes and sequence characterization. Journal of Phycology, 37, 64–70.
Arciero, D. M., Bryant, D. A., & Glazer, A. N. (1988). In vitro attachment of bilins to apophycocyanin I: Specific covalent adduct formation at cysteinyl residues involved in phycocyanobilin
binding in C-phycocyanin. Journal of Biological Chemistry, 263, 18343–18349.
Beale, S. I., & Cornejo, J. (1991). Biosynthesis of phycobilins. Ferredoxin-mediated reduction of
biliverdin catalyzed by extracts of Cyanidium caldarium. Journal of Biological Chemistry, 266,
22328–22332.
Belkin, S., & Boussiba, S. (1991). High internal pH conveys ammonia resistance in Spirulina
platensis. Bioresource Technology, 38, 167–169.
Benedetti, S., Benvenuti, F., Scoglio, S., & Canestrari, F. (2010). Oxygen radical absorbance capacity
of phycocyanin and phycocyanobilin from the food supplement Aphanizomenon flos-aquae.
Journal of Medicinal Food, 13, 223–227.