356
J. Jeevanandam et al.
Khan, M. I., Shin, J. H., & Kim, J. D. (2018). The promising future of microalgae: Current Status,
Challenges, And Optimization Of A Sustainable And Renewable Industry For Biofuels, Feed,
And Other Products. Microbial Cell Factories, 17, 36.
Khanra, S., Mondal, M., Halder, G., Tiwari, O. N., Gayen, K., & Bhowmick, T. K. (2018). Downstream processing of microalgae for pigments, protein and carbohydrate in industrial application:
A review. Food and Bioproducts Processing, 110, 60–84.
Kidd, P. (2011). Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging
potential. Alternative Medicine Review, 16, 355–364.
Kim, S. M., Jung, Y. J., Kwon, O. N., Cha, K. H., Um, B. H., Chung, D., et al. (2012). A potential
commercial source of fucoxanthin extracted from the microalga phaeodactylum tricornutum.
Applied Biochemistry and Biotechnology, 166, 1843–1855.
Kim, Y. J., Kim, Y. A., & Yokozawa, T. (2009). Protection against oxidative stress, inflammation,
and apoptosis of high-glucose-exposed proximal tubular epithelial cells by astaxanthin. Journal
of Agriculture and Food Chemistry, 57, 8793–8797.
Kleinegris, D. M., Janssen, M., Brandenburg, W. A., & Wijffels, R. H. (2011). Continuous production
of carotenoids from dunaliella salina. Enyzme and Microbial Technology, 48, 253–259.
Kotake-Nara, E., Kushiro, M., Zhang, H., Sugawara, T., Miyashita, K., & Nagao, A. (2001).
Carotenoids affect proliferation of human prostate cancer cells. Journal of Nutrition, 131,
3303–3306.
Krishnaswamy, S. (2018). Bioprospecting, botany, biodiversity, and their impact on botanical drug
development. Botanical Drug Products: Recent Developments and Market Trends, 39.
Kronick, M. N., & Grossman, P. D. (1983). Immunoassay techniques with fluorescent phycobiliprotein conjugates. Clinical Chemistry, 29, 1582–1586.
Kuddus, M., Singh, P., Thomas, G., & Al-Hazimi, A. (2013). Recent developments in production and
biotechnological applications of C-phycocyanin. BioMed Research International, 2013, 742859.
Kumar, S. R., Hosokawa, M., & Miyashita, K. (2013). Fucoxanthin: A marine carotenoid exerting
anti-cancer effects by affecting multiple mechanisms. Mar Drugs, 11, 5130–5147.
Lee, K., Eisterhold, M. L., Rindi, F., Palanisami, S., & Nam, P. K. (2014). isolation and screening
of microalgae from natural habitats in the midwestern United States of America for biomass and
biodiesel sources. Journal of Natural Science, Biology, and Medicine, 5, 333.
Lee, Y.-C., Lee, K., & Oh, Y.-K. (2015). Recent nanoparticle engineering advances in microalgal
cultivation and harvesting processes of biodiesel production: A review. Bioresource Technology,
184, 63–72.
Lemoine, Y., & Schoefs, B. (2010). Secondary ketocarotenoid astaxanthin biosynthesis in algae: A
multifunctional response to stress. Photosynthesis Research, 106, 155–177.
Li, Z., Ma, X., Li, A., & Zhang, C. (2012a). A novel potential source of beta-carotene: Eustigmatos
Cf. Polyphem (Eustigmatophyceae) and pilot beta-carotene production in bubble column and flat
panel photobioreactors. Bioresource Technology, 117, 257–263.
Li, Z., Sun, M., Li, Q., Li, A., & Zhang, C. (2012b). Profiling Of Carotenoids In Six Microalgae
(Eustigmatophyceae) and assessment of their beta-carotene productions in bubble column
photobioreactor. Biotechnology Letters, 34, 2049–2053.
Lin, K. H., Lin, K. C., Lu, W. J., Thomas, P. A., Jayakumar, T., & Sheu, J. R. (2015). Astaxanthin, a
carotenoid, stimulates immune responses by enhancing ifn-gamma and Il-2 secretion in primary
cultured lymphocytes in vitro and ex vivo. International Journal of Molecular Sciences, 17.
Lopez, M. C., Sanchez Edel, R., Lopez, J. L., Fernandez, F. G., Sevilla, J. M., Rivas, J., et al. (2006).
Comparative analysis of the outdoor culture of haematococcus pluvialis in tubular and bubble
column photobioreactors. Journal of Biotechnology, 123, 329–342.
Ma, R. Y. N., & Chen, F. (2001). Enhanced production of free trans-astaxanthin by oxidative stress
in the cultures of the green microalga chlorococcum Sp. Process Biochemistry, 36, 1175–1179.
Macias-Sanchez, M. D., Mantell, C., Rodriguez, M., Martinez De La Ossa, E., Lubian, L. M.,
& Montero, O. (2009). Comparison of supercritical fluid and ultrasound-assisted extraction of
carotenoids and chlorophyll a from dunaliella salina. Talanta, 77, 948–952.
J. Jeevanandam et al.
Khan, M. I., Shin, J. H., & Kim, J. D. (2018). The promising future of microalgae: Current Status,
Challenges, And Optimization Of A Sustainable And Renewable Industry For Biofuels, Feed,
And Other Products. Microbial Cell Factories, 17, 36.
Khanra, S., Mondal, M., Halder, G., Tiwari, O. N., Gayen, K., & Bhowmick, T. K. (2018). Downstream processing of microalgae for pigments, protein and carbohydrate in industrial application:
A review. Food and Bioproducts Processing, 110, 60–84.
Kidd, P. (2011). Astaxanthin, cell membrane nutrient with diverse clinical benefits and anti-aging
potential. Alternative Medicine Review, 16, 355–364.
Kim, S. M., Jung, Y. J., Kwon, O. N., Cha, K. H., Um, B. H., Chung, D., et al. (2012). A potential
commercial source of fucoxanthin extracted from the microalga phaeodactylum tricornutum.
Applied Biochemistry and Biotechnology, 166, 1843–1855.
Kim, Y. J., Kim, Y. A., & Yokozawa, T. (2009). Protection against oxidative stress, inflammation,
and apoptosis of high-glucose-exposed proximal tubular epithelial cells by astaxanthin. Journal
of Agriculture and Food Chemistry, 57, 8793–8797.
Kleinegris, D. M., Janssen, M., Brandenburg, W. A., & Wijffels, R. H. (2011). Continuous production
of carotenoids from dunaliella salina. Enyzme and Microbial Technology, 48, 253–259.
Kotake-Nara, E., Kushiro, M., Zhang, H., Sugawara, T., Miyashita, K., & Nagao, A. (2001).
Carotenoids affect proliferation of human prostate cancer cells. Journal of Nutrition, 131,
3303–3306.
Krishnaswamy, S. (2018). Bioprospecting, botany, biodiversity, and their impact on botanical drug
development. Botanical Drug Products: Recent Developments and Market Trends, 39.
Kronick, M. N., & Grossman, P. D. (1983). Immunoassay techniques with fluorescent phycobiliprotein conjugates. Clinical Chemistry, 29, 1582–1586.
Kuddus, M., Singh, P., Thomas, G., & Al-Hazimi, A. (2013). Recent developments in production and
biotechnological applications of C-phycocyanin. BioMed Research International, 2013, 742859.
Kumar, S. R., Hosokawa, M., & Miyashita, K. (2013). Fucoxanthin: A marine carotenoid exerting
anti-cancer effects by affecting multiple mechanisms. Mar Drugs, 11, 5130–5147.
Lee, K., Eisterhold, M. L., Rindi, F., Palanisami, S., & Nam, P. K. (2014). isolation and screening
of microalgae from natural habitats in the midwestern United States of America for biomass and
biodiesel sources. Journal of Natural Science, Biology, and Medicine, 5, 333.
Lee, Y.-C., Lee, K., & Oh, Y.-K. (2015). Recent nanoparticle engineering advances in microalgal
cultivation and harvesting processes of biodiesel production: A review. Bioresource Technology,
184, 63–72.
Lemoine, Y., & Schoefs, B. (2010). Secondary ketocarotenoid astaxanthin biosynthesis in algae: A
multifunctional response to stress. Photosynthesis Research, 106, 155–177.
Li, Z., Ma, X., Li, A., & Zhang, C. (2012a). A novel potential source of beta-carotene: Eustigmatos
Cf. Polyphem (Eustigmatophyceae) and pilot beta-carotene production in bubble column and flat
panel photobioreactors. Bioresource Technology, 117, 257–263.
Li, Z., Sun, M., Li, Q., Li, A., & Zhang, C. (2012b). Profiling Of Carotenoids In Six Microalgae
(Eustigmatophyceae) and assessment of their beta-carotene productions in bubble column
photobioreactor. Biotechnology Letters, 34, 2049–2053.
Lin, K. H., Lin, K. C., Lu, W. J., Thomas, P. A., Jayakumar, T., & Sheu, J. R. (2015). Astaxanthin, a
carotenoid, stimulates immune responses by enhancing ifn-gamma and Il-2 secretion in primary
cultured lymphocytes in vitro and ex vivo. International Journal of Molecular Sciences, 17.
Lopez, M. C., Sanchez Edel, R., Lopez, J. L., Fernandez, F. G., Sevilla, J. M., Rivas, J., et al. (2006).
Comparative analysis of the outdoor culture of haematococcus pluvialis in tubular and bubble
column photobioreactors. Journal of Biotechnology, 123, 329–342.
Ma, R. Y. N., & Chen, F. (2001). Enhanced production of free trans-astaxanthin by oxidative stress
in the cultures of the green microalga chlorococcum Sp. Process Biochemistry, 36, 1175–1179.
Macias-Sanchez, M. D., Mantell, C., Rodriguez, M., Martinez De La Ossa, E., Lubian, L. M.,
& Montero, O. (2009). Comparison of supercritical fluid and ultrasound-assisted extraction of
carotenoids and chlorophyll a from dunaliella salina. Talanta, 77, 948–952.