6 Retinoic Acid Signaling and Development of the Respiratory System
173
Niederreither K, Dolle P (2008) Retinoic acid in development: towards an integrated view. Nat Rev
Genet 9:541–553
Niederreither K, Subbarayan V, Dolle P, Chambon P (1999) Embryonic retinoic acid synthesis is
essential for early mouse post-implantation development. Nat Genet 21:444–448
Noy N (2016) Vitamin A Transport and Cell Signaling by the Retinol-Binding Protein Receptor
STRA6. Sub-Cell Biochem 81:77–93
Okabe T, Yorifuji H, Yamada E, Takaku F (1984) Isolation and characterization of vitamin-A-storing
lung cells. Exp Cell Res 154:125–135
Pasutto F, Sticht H, Hammersen G, Gillessen-Kaesbach G, Fitzpatrick DR, Nurnberg G, Brasch F,
Schirmer-Zimmermann H, Tolmie JL, Chitayat D, Houge G, Fernandez-Martinez L, Keating S,
Mortier G, Hennekam RC, von der Wense A, Slavotinek A, Meinecke P, Bitoun P, Becker C,
Nurnberg P, Reis A, Rauch A (2007) Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary
dysplasia, lung hypoplasia, and mental retardation. Am J Human Genet 80:550–560.
Pringle KC (1986) Human fetal lung development and related animal models. Clin Obstet Gynecol
29:502–513
Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan
BL (2007) Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior
foregut endoderm. Development 134:2521–2531
Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM,
Shannon JM, Zorn AM (2016) A Retinoic Acid-Hedgehog Cascade Coordinates MesodermInducing Signals and Endoderm Competence during Lung Specification. Cell Rep 16:66–78
Rankin SA, Thi Tran H, Wlizla M, Mancini P, Shifley ET, Bloor SD, Han L, Vleminckx K, Wert
SE, Zorn AM (2015) A molecular atlas of xenopus respiratory system development. Dev Dyn
244:69–85
Rossant J, Zirngibl R, Cado D, Shago M, Giguere V (1991) Expression of a retinoic acid response
element-hsplacZ transgene defines specific domains of transcriptional activity during mouse
embryogenesis. Genes Dev 5:1333–1344
Sandell LL, Sanderson BW, Moiseyev G, Johnson T, Mushegian A, Young K, Rey JP, Ma JX,
Staehling-Hampton K, Trainor PA (2007) RDH10 is essential for synthesis of embryonic retinoic
acid and is required for limb, craniofacial, and organ development. Genes Dev 21:1113–1124
Schittny JC (2017) Development of the lung. Cell Tissue Res 367:427–444
Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, Yagishita N, Matsui D, Koga
Y, Itoh N, Kato S (1999) Fgf10 is essential for limb and lung formation. Nat Genet 21:138–141
Shenai JP, Chytil F, Stahlman MT (1985) Vitamin A status of neonates with bronchopulmonary
dysplasia. Pediatr Res 19:185–188
Shifley ET, Kenny AP, Rankin SA, Zorn AM (2012) Prolonged FGF signaling is necessary for lung
and liver induction in Xenopus. BMC Dev Biol 12:27
Snyder JM, Jenkins-Moore M, Jackson SK, Goss KL, Dai HH, Bangsund PJ, Giguere V, McGowan
SE (2005) Alveolarization in retinoic acid receptor-beta-deficient mice. Pediatr Res 57:384–391
Tahayato A, Dolle P, Petkovich M (2003) Cyp26C1 encodes a novel retinoic acid-metabolizing
enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine
development. Gene Expr Patterns : GEP 3:449–454
Thebaud B, Tibboel D, Rambaud C, Mercier JC, Bourbon JR, Dinh-Xuan AT, Archer SL (1999)
Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic
hernia in rats. Am J Physiol 277:L423–429
Torfs CP, Curry CJ, Bateson TF, Honore LH (1992) A population-based study of congenital
diaphragmatic hernia. Teratology 46:555–565
Wang JH, Deimling SJ, D’Alessandro NE, Zhao L, Possmayer F, Drysdale TA (2011) Retinoic acid
is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus
laevis. BMC Dev Biol 11:75
173
Niederreither K, Dolle P (2008) Retinoic acid in development: towards an integrated view. Nat Rev
Genet 9:541–553
Niederreither K, Subbarayan V, Dolle P, Chambon P (1999) Embryonic retinoic acid synthesis is
essential for early mouse post-implantation development. Nat Genet 21:444–448
Noy N (2016) Vitamin A Transport and Cell Signaling by the Retinol-Binding Protein Receptor
STRA6. Sub-Cell Biochem 81:77–93
Okabe T, Yorifuji H, Yamada E, Takaku F (1984) Isolation and characterization of vitamin-A-storing
lung cells. Exp Cell Res 154:125–135
Pasutto F, Sticht H, Hammersen G, Gillessen-Kaesbach G, Fitzpatrick DR, Nurnberg G, Brasch F,
Schirmer-Zimmermann H, Tolmie JL, Chitayat D, Houge G, Fernandez-Martinez L, Keating S,
Mortier G, Hennekam RC, von der Wense A, Slavotinek A, Meinecke P, Bitoun P, Becker C,
Nurnberg P, Reis A, Rauch A (2007) Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary
dysplasia, lung hypoplasia, and mental retardation. Am J Human Genet 80:550–560.
Pringle KC (1986) Human fetal lung development and related animal models. Clin Obstet Gynecol
29:502–513
Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan
BL (2007) Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior
foregut endoderm. Development 134:2521–2531
Rankin SA, Han L, McCracken KW, Kenny AP, Anglin CT, Grigg EA, Crawford CM, Wells JM,
Shannon JM, Zorn AM (2016) A Retinoic Acid-Hedgehog Cascade Coordinates MesodermInducing Signals and Endoderm Competence during Lung Specification. Cell Rep 16:66–78
Rankin SA, Thi Tran H, Wlizla M, Mancini P, Shifley ET, Bloor SD, Han L, Vleminckx K, Wert
SE, Zorn AM (2015) A molecular atlas of xenopus respiratory system development. Dev Dyn
244:69–85
Rossant J, Zirngibl R, Cado D, Shago M, Giguere V (1991) Expression of a retinoic acid response
element-hsplacZ transgene defines specific domains of transcriptional activity during mouse
embryogenesis. Genes Dev 5:1333–1344
Sandell LL, Sanderson BW, Moiseyev G, Johnson T, Mushegian A, Young K, Rey JP, Ma JX,
Staehling-Hampton K, Trainor PA (2007) RDH10 is essential for synthesis of embryonic retinoic
acid and is required for limb, craniofacial, and organ development. Genes Dev 21:1113–1124
Schittny JC (2017) Development of the lung. Cell Tissue Res 367:427–444
Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, Yagishita N, Matsui D, Koga
Y, Itoh N, Kato S (1999) Fgf10 is essential for limb and lung formation. Nat Genet 21:138–141
Shenai JP, Chytil F, Stahlman MT (1985) Vitamin A status of neonates with bronchopulmonary
dysplasia. Pediatr Res 19:185–188
Shifley ET, Kenny AP, Rankin SA, Zorn AM (2012) Prolonged FGF signaling is necessary for lung
and liver induction in Xenopus. BMC Dev Biol 12:27
Snyder JM, Jenkins-Moore M, Jackson SK, Goss KL, Dai HH, Bangsund PJ, Giguere V, McGowan
SE (2005) Alveolarization in retinoic acid receptor-beta-deficient mice. Pediatr Res 57:384–391
Tahayato A, Dolle P, Petkovich M (2003) Cyp26C1 encodes a novel retinoic acid-metabolizing
enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine
development. Gene Expr Patterns : GEP 3:449–454
Thebaud B, Tibboel D, Rambaud C, Mercier JC, Bourbon JR, Dinh-Xuan AT, Archer SL (1999)
Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic
hernia in rats. Am J Physiol 277:L423–429
Torfs CP, Curry CJ, Bateson TF, Honore LH (1992) A population-based study of congenital
diaphragmatic hernia. Teratology 46:555–565
Wang JH, Deimling SJ, D’Alessandro NE, Zhao L, Possmayer F, Drysdale TA (2011) Retinoic acid
is a key regulatory switch determining the difference between lung and thyroid fates in Xenopus
laevis. BMC Dev Biol 11:75