10.12.4 Retigeranic Acid B
The gene for the biosynthesis of retigeranin B (173) has been found in the genome
from the plant Arabidopsis thaliana (Fig. 120) [131, 135]. Compound 173 is
considered to be a biosynthetic intermediate of retigeranic acid B (137).
10.12.5 Astellatol
The gene for the production of astellatene (174) has been identified in the genome
from the plant Arabidopsis thaliana (Fig. 121) [131]. Compound 174 might be a
precursor of astellatol (133). Incidentally, the genes for the production of 174
(Fig. 121) and ent-140 (Fig. 101) reportedly play an important role in the root
microbiota assembly of the plant [153]. This is one of the few examples of an
investigation into the biological roles of sesterterpenoids.
OH
HO
OH
OH
125
172
Fig. 119 Structures of 172 and 125. The structure of 125 is also shown in Fig. 90
COOH
137
173
Fig. 120 Structures of 173 and 137. The structure of 137 is also shown in Fig. 98
OH
133
174
Fig. 121 Structures of 174 and 133. The structure of 133 is also shown in Fig. 96
Sesterterpenoids
69