e.g., in the case of propranolol, ciprofloxacin, metoprolol, tramadol, atenolol (Rai
et al. 2018). In the case of β-blockers, due to their different structure, different
reaction pathways are observed. Generally, initial cleavage of an aromatic ring was
observed. Carbonyl products were formed with subsequent transformation to a
hydroxylamine derivative after the attack of ferrate on the amine moiety (Sharma
et al. 2016a). Some analgesics react with ferrate(VI) very slowly. In case of
tramadol, estimated degradation half-time is several minutes. Initially, ferrate reacts
Fig. 8.6 Degradation of
estrone by ferrate
(VI) (Adapted from
Machalová Šišková et al.
2016)
190
L. Machala et al.
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