9 Aptamers for the Diagnosis of Malign Tumors
269
9. Mayer G (2009) The chemical biology of aptamers. Angew Chem Int Ed 48(15):2672–2689
10. Song S, Wang L, Li J, Fan C, Zhao J (2008) Aptamer-based biosensors. TrAC Trends Anal
Chem 27(2):108–117
11. Cox JC, Ellington AD (2001) Automated selection of anti-protein aptamers. Biorg Med Chem
9(10):2525–2531
12. Liu J, Cao Z, Lu Y (2009) Functional nucleic acid sensors. Chem Rev 109(5):1948–1998
13. Dalton WS, Friend SH (2006) Cancer biomarkers-an invitation to the table. Science
312(5777):1165–1168
14. Aebersold R, Anderson L, Caprioli R, Druker B, Hartwell L, Smith R (2005) Perspective: a
program to improve protein biomarker discovery for cancer. J Proteome Res 4(4):1104–1109
15. Mallick P, Kuster B (2010) Proteomics: a pragmatic perspective. Nat Biotechnol 28(7):695
16. Jain KK, Jain KK (2010) The handbook of biomarkers. Springer
17. Hood LE, Omenn GS, Moritz RL, Aebersold R, Yamamoto KR, Amos M, Hunter-Cevera J,
Locascio L, Participants W (2012) New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences.
Proteomics 12(18):2773–2783
18. Ray P, Rialon-Guevara KL, Veras E, Sullenger BA, White RR (2012) Comparing human
pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate
pancreatic cancer biomarker. J Clin Invest 122(5):1734–1741
19. Pang X, Cui C, Wan S, Jiang Y, Zhang L, Xia L, Li L, Li X, Tan W (2018) Bioapplications of cell-SELEX-generated aptamers in cancer diagnostics, therapeutics, theranostics and
biomarker discovery: a comprehensive review. Cancers 10(2):47
20. Ma H, Liu J, Ali MM, Mahmood MAI, Labanieh L, Lu M, Iqbal SM, Zhang Q, Zhao W, Wan
Y (2015) Nucleic acid aptamers in cancer research, diagnosis and therapy. Chem Soc Rev
44(5):1240–1256
21. Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L (2003) A tenascin-C aptamer identified
by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment. Proc Natl
Acad Sci USA 100(26):15416–15421
22. Shangguan D, Li Y, Tang Z, Cao ZC, Chen HW, Mallikaratchy P, Sefah K, Yang CJ, Tan W
(2006) Aptamers evolved from live cells as effective molecular probes for cancer study. Proc
Natl Acad Sci USA 103(32):11838–11843
23. Mallikaratchy P, Tang Z, Kwame S, Meng L, Shangguan D, Tan W (2007) Aptamer directly
evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in
Burkitt’s lymphoma cells. Mol Cell Proteomics 6(12):2230–2238
24. Xiong H, Yan J, Cai S, He Q, Peng D, Liu Z, Liu Y (2019) Cancer protein biomarker discovery
based on nucleic acid aptamers. Int J Biol Macromol 132:190–202
25. Fang X, Tan W (2010) Aptamers generated from cell-SELEX for molecular medicine: a
chemical biology approach. Acc Chem Res 43(1):48–57
26. Li S, Xu H, Ding H, Huang Y, Cao X, Yang G, Li J, Xie Z, Meng Y, Li X, Zhao Q, Shen B,
Shao N (2009) Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX.
J Pathol 218(3):327–336
27. Mi J, Liu Y, Rabbani ZN, Yang Z, Urban JH, Sullenger BA, Clary BM (2010) In vivo selection
of tumor-targeting RNA motifs. Nat Chem Biol 6(1):22–24
28. Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE,
Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta
S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E,
Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B,
Mayfield W, Mehan M, Mehler R, Nelson SK, Nelson M, Nieuwlandt D, Nikrad M, Ochsner
U, Ostroff RM, Otis M, Parker T, Pietrasiewicz S, Resnicow DI, Rohloff J, Sanders G, Sattin
S, Schneider D, Singer B, Stanton M, Sterkel A, Stewart A, Stratford S, Vaught JD, Vrkljan
M, Walker JJ, Watrobka M, Waugh S, Weiss A, Wilcox SK, Wolfson A, Wolk SK, Zhang C,
Zichi D (2010) Aptamer-based multiplexed proteomic technology for biomarker discovery.
PLoS ONE 5(12):e15004
269
9. Mayer G (2009) The chemical biology of aptamers. Angew Chem Int Ed 48(15):2672–2689
10. Song S, Wang L, Li J, Fan C, Zhao J (2008) Aptamer-based biosensors. TrAC Trends Anal
Chem 27(2):108–117
11. Cox JC, Ellington AD (2001) Automated selection of anti-protein aptamers. Biorg Med Chem
9(10):2525–2531
12. Liu J, Cao Z, Lu Y (2009) Functional nucleic acid sensors. Chem Rev 109(5):1948–1998
13. Dalton WS, Friend SH (2006) Cancer biomarkers-an invitation to the table. Science
312(5777):1165–1168
14. Aebersold R, Anderson L, Caprioli R, Druker B, Hartwell L, Smith R (2005) Perspective: a
program to improve protein biomarker discovery for cancer. J Proteome Res 4(4):1104–1109
15. Mallick P, Kuster B (2010) Proteomics: a pragmatic perspective. Nat Biotechnol 28(7):695
16. Jain KK, Jain KK (2010) The handbook of biomarkers. Springer
17. Hood LE, Omenn GS, Moritz RL, Aebersold R, Yamamoto KR, Amos M, Hunter-Cevera J,
Locascio L, Participants W (2012) New and improved proteomics technologies for understanding complex biological systems: addressing a grand challenge in the life sciences.
Proteomics 12(18):2773–2783
18. Ray P, Rialon-Guevara KL, Veras E, Sullenger BA, White RR (2012) Comparing human
pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate
pancreatic cancer biomarker. J Clin Invest 122(5):1734–1741
19. Pang X, Cui C, Wan S, Jiang Y, Zhang L, Xia L, Li L, Li X, Tan W (2018) Bioapplications of cell-SELEX-generated aptamers in cancer diagnostics, therapeutics, theranostics and
biomarker discovery: a comprehensive review. Cancers 10(2):47
20. Ma H, Liu J, Ali MM, Mahmood MAI, Labanieh L, Lu M, Iqbal SM, Zhang Q, Zhao W, Wan
Y (2015) Nucleic acid aptamers in cancer research, diagnosis and therapy. Chem Soc Rev
44(5):1240–1256
21. Daniels DA, Chen H, Hicke BJ, Swiderek KM, Gold L (2003) A tenascin-C aptamer identified
by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment. Proc Natl
Acad Sci USA 100(26):15416–15421
22. Shangguan D, Li Y, Tang Z, Cao ZC, Chen HW, Mallikaratchy P, Sefah K, Yang CJ, Tan W
(2006) Aptamers evolved from live cells as effective molecular probes for cancer study. Proc
Natl Acad Sci USA 103(32):11838–11843
23. Mallikaratchy P, Tang Z, Kwame S, Meng L, Shangguan D, Tan W (2007) Aptamer directly
evolved from live cells recognizes membrane bound immunoglobin heavy mu chain in
Burkitt’s lymphoma cells. Mol Cell Proteomics 6(12):2230–2238
24. Xiong H, Yan J, Cai S, He Q, Peng D, Liu Z, Liu Y (2019) Cancer protein biomarker discovery
based on nucleic acid aptamers. Int J Biol Macromol 132:190–202
25. Fang X, Tan W (2010) Aptamers generated from cell-SELEX for molecular medicine: a
chemical biology approach. Acc Chem Res 43(1):48–57
26. Li S, Xu H, Ding H, Huang Y, Cao X, Yang G, Li J, Xie Z, Meng Y, Li X, Zhao Q, Shen B,
Shao N (2009) Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX.
J Pathol 218(3):327–336
27. Mi J, Liu Y, Rabbani ZN, Yang Z, Urban JH, Sullenger BA, Clary BM (2010) In vivo selection
of tumor-targeting RNA motifs. Nat Chem Biol 6(1):22–24
28. Gold L, Ayers D, Bertino J, Bock C, Bock A, Brody EN, Carter J, Dalby AB, Eaton BE,
Fitzwater T, Flather D, Forbes A, Foreman T, Fowler C, Gawande B, Goss M, Gunn M, Gupta
S, Halladay D, Heil J, Heilig J, Hicke B, Husar G, Janjic N, Jarvis T, Jennings S, Katilius E,
Keeney TR, Kim N, Koch TH, Kraemer S, Kroiss L, Le N, Levine D, Lindsey W, Lollo B,
Mayfield W, Mehan M, Mehler R, Nelson SK, Nelson M, Nieuwlandt D, Nikrad M, Ochsner
U, Ostroff RM, Otis M, Parker T, Pietrasiewicz S, Resnicow DI, Rohloff J, Sanders G, Sattin
S, Schneider D, Singer B, Stanton M, Sterkel A, Stewart A, Stratford S, Vaught JD, Vrkljan
M, Walker JJ, Watrobka M, Waugh S, Weiss A, Wilcox SK, Wolfson A, Wolk SK, Zhang C,
Zichi D (2010) Aptamer-based multiplexed proteomic technology for biomarker discovery.
PLoS ONE 5(12):e15004