308
M. J. Huttunen and A. Kiviniemi
11. E. Betzig, G.H. Patterson, R. Sougrat, O.W. Lindwasser, S. Olenych, J.S. Bonifacino, M.W.
Davidson, J. Lippincott-Schwartz, H.F. Hess, Imaging intracellular fluorescent proteins at
nanometer resolution. Science 313(5793), 1642–1645 (2006)
12. M.G.L. Gustafsson, Surpassing the lateral resolution limit by a factor of two using structured
illumination microscopy. J. Microsc. 198(2), 82–87 (2000)
13. A.K. Dunn, H. Bolay, M.A. Moskowitz, D.A. Boas, Dynamic imaging of cerebral blood flow
using laser speckle. J. Cereb. Blood Flow Metab. 21(3), 195–201 (2001)
14. P. Marquet, B. Rappaz, P.J. Magistretti, E. Cuche, Y. Emery, T. Colomb, C. Depeursinge, Digital holographic microscopy: a noninvasive contrast imaging technique allowing quantitative
visualization of living cells with subwavelength axial accuracy. Opt. Lett. 30(5), 468–470
(2005)
15. F. Jünger, P.V. Olshausen, A. Rohrbach, Fast, label-free super-resolution live-cell imaging
using rotating coherent scattering (ROCS) microscopy. Sci. Rep. 6, 30393 (2016)
16. W. Denk, J. Strickler, W. Webb, Two-photon laser scanning fluorescence microscopy. Science
248(4951), 73–76 (1990)
17. R.W. Boyd, Nonlinear Optics (Academic Press, San Diego, 2003)
18. W.P. Beeker, P. Gross, C.J. Lee, C. Cleff, H.L. Offerhaus, C. Fallnich, J.L. Herek, K.-J. Boller,
A route to sub-diffraction-limited CARS microscopy. Opt. Express 17(25), 22632–22638
(2009)
19. K.M. Hajek, B. Littleton, D. Turk, T.J. McIntyre, H. Rubinsztein-Dunlop, A method for
achieving super-resolved widefield CARS microscopy. Opt. Express 18(18), 19263–19272
(2010)
20. H. Kim, G.W. Bryant, S.J. Stranick, Superresolution four-wave mixing microscopy. Opt.
Express 20(6), 6042–6051 (2012)
21. J.H. Park, S.-W. Lee, E.S. Lee, J.Y. Lee, A method for super-resolved CARS microscopy with
structured illumination in two dimensions. Opt. Express 22(8), 9854–9870 (2014)
22. J.J. Field, K.W. Wernsing, S.R. Domingue, A.M.A. Motz, K.F. DeLuca, J.G. DeLuca, D.
Kuciauskas, D.H. Levi, J.A. Squier, R.A. Bartels, Super-resolved multimodal multiphoton
microscopy with spatial frequency-modulated imaging. Proc. Natl. Acad. Sci. 113(24), 6605–
6610 (2015)
23. M.J. Huttunen, A. Abbas, J. Upham, R.W. Boyd, Label-free super-resolution with coherent
nonlinear structured-illumination microscopy. J. Opt. 19(8), 085504 (2017)
24. R. Heintzmann, T.M. Jovin, C. Cremer, Saturated patterned excitation microscopya concept
for optical resolution improvement. J. Opt. Soc. Am. A 19(8), 1599–1609 (2002)
25. E.H. Rego, L. Shao, J.J. Macklin, L. Winoto, G.A. Johansson, N. Kamps-Hughes, M.W.
Davidson, M.G.L. Gustafsson, Nonlinear structured-illumination microscopy with a photoswitchable protein reveals cellular structures at 50-nm resolution. Proc. Natl. Acad. Sci.
109(3), E135–E143 (2012)
26. S. Van Aert, D. Van Dyck, A.J. den Dekker, Resolution of coherent and incoherent imaging systems reconsidered—classical criteria and a statistical alternative. Opt. Express 14(9),
3830–3839 (2006)
27. C.-H. Yeh, S.-Y. Chen, Resolution enhancement of two-photon microscopy via intensitymodulated laser scanning structured illumination. Appl. Opt. 54(9), 2309–2317 (2015)
28. K. Toda, K. Isobe, K. Namiki, H. Kawano, A. Miyawaki, K. Midorikawa, Interferometric temporal focusing microscopy using three-photon excitation fluorescence. Biomed. Opt. Express
20(4), 237–239 (2018)
29. R. Heintzmann, T. Huser, Super-resolution structured illumination microscopy. Chem. Rev.
117(23), 13890–13908 (2017)
30. M.A.A. Neil, R. Juškaitis, T. Wilson, Method of obtaining optical sectioning by using structured light in a conventional microscope. Opt. Lett. 22(24), 1905–1907 (1997)
31. M. Ingaramo, A.G. York, P. Wawrzusin, O. Milberg, A. Hong, R. Weigert, H. Shroff, G.H.
Patterson, Two-photon excitation improves multifocal structured illumination microscopy in
thick scattering tissue. Proc. Natl. Acad. Sci. 111(14), 5254–5259 (2014)
M. J. Huttunen and A. Kiviniemi
11. E. Betzig, G.H. Patterson, R. Sougrat, O.W. Lindwasser, S. Olenych, J.S. Bonifacino, M.W.
Davidson, J. Lippincott-Schwartz, H.F. Hess, Imaging intracellular fluorescent proteins at
nanometer resolution. Science 313(5793), 1642–1645 (2006)
12. M.G.L. Gustafsson, Surpassing the lateral resolution limit by a factor of two using structured
illumination microscopy. J. Microsc. 198(2), 82–87 (2000)
13. A.K. Dunn, H. Bolay, M.A. Moskowitz, D.A. Boas, Dynamic imaging of cerebral blood flow
using laser speckle. J. Cereb. Blood Flow Metab. 21(3), 195–201 (2001)
14. P. Marquet, B. Rappaz, P.J. Magistretti, E. Cuche, Y. Emery, T. Colomb, C. Depeursinge, Digital holographic microscopy: a noninvasive contrast imaging technique allowing quantitative
visualization of living cells with subwavelength axial accuracy. Opt. Lett. 30(5), 468–470
(2005)
15. F. Jünger, P.V. Olshausen, A. Rohrbach, Fast, label-free super-resolution live-cell imaging
using rotating coherent scattering (ROCS) microscopy. Sci. Rep. 6, 30393 (2016)
16. W. Denk, J. Strickler, W. Webb, Two-photon laser scanning fluorescence microscopy. Science
248(4951), 73–76 (1990)
17. R.W. Boyd, Nonlinear Optics (Academic Press, San Diego, 2003)
18. W.P. Beeker, P. Gross, C.J. Lee, C. Cleff, H.L. Offerhaus, C. Fallnich, J.L. Herek, K.-J. Boller,
A route to sub-diffraction-limited CARS microscopy. Opt. Express 17(25), 22632–22638
(2009)
19. K.M. Hajek, B. Littleton, D. Turk, T.J. McIntyre, H. Rubinsztein-Dunlop, A method for
achieving super-resolved widefield CARS microscopy. Opt. Express 18(18), 19263–19272
(2010)
20. H. Kim, G.W. Bryant, S.J. Stranick, Superresolution four-wave mixing microscopy. Opt.
Express 20(6), 6042–6051 (2012)
21. J.H. Park, S.-W. Lee, E.S. Lee, J.Y. Lee, A method for super-resolved CARS microscopy with
structured illumination in two dimensions. Opt. Express 22(8), 9854–9870 (2014)
22. J.J. Field, K.W. Wernsing, S.R. Domingue, A.M.A. Motz, K.F. DeLuca, J.G. DeLuca, D.
Kuciauskas, D.H. Levi, J.A. Squier, R.A. Bartels, Super-resolved multimodal multiphoton
microscopy with spatial frequency-modulated imaging. Proc. Natl. Acad. Sci. 113(24), 6605–
6610 (2015)
23. M.J. Huttunen, A. Abbas, J. Upham, R.W. Boyd, Label-free super-resolution with coherent
nonlinear structured-illumination microscopy. J. Opt. 19(8), 085504 (2017)
24. R. Heintzmann, T.M. Jovin, C. Cremer, Saturated patterned excitation microscopya concept
for optical resolution improvement. J. Opt. Soc. Am. A 19(8), 1599–1609 (2002)
25. E.H. Rego, L. Shao, J.J. Macklin, L. Winoto, G.A. Johansson, N. Kamps-Hughes, M.W.
Davidson, M.G.L. Gustafsson, Nonlinear structured-illumination microscopy with a photoswitchable protein reveals cellular structures at 50-nm resolution. Proc. Natl. Acad. Sci.
109(3), E135–E143 (2012)
26. S. Van Aert, D. Van Dyck, A.J. den Dekker, Resolution of coherent and incoherent imaging systems reconsidered—classical criteria and a statistical alternative. Opt. Express 14(9),
3830–3839 (2006)
27. C.-H. Yeh, S.-Y. Chen, Resolution enhancement of two-photon microscopy via intensitymodulated laser scanning structured illumination. Appl. Opt. 54(9), 2309–2317 (2015)
28. K. Toda, K. Isobe, K. Namiki, H. Kawano, A. Miyawaki, K. Midorikawa, Interferometric temporal focusing microscopy using three-photon excitation fluorescence. Biomed. Opt. Express
20(4), 237–239 (2018)
29. R. Heintzmann, T. Huser, Super-resolution structured illumination microscopy. Chem. Rev.
117(23), 13890–13908 (2017)
30. M.A.A. Neil, R. Juškaitis, T. Wilson, Method of obtaining optical sectioning by using structured light in a conventional microscope. Opt. Lett. 22(24), 1905–1907 (1997)
31. M. Ingaramo, A.G. York, P. Wawrzusin, O. Milberg, A. Hong, R. Weigert, H. Shroff, G.H.
Patterson, Two-photon excitation improves multifocal structured illumination microscopy in
thick scattering tissue. Proc. Natl. Acad. Sci. 111(14), 5254–5259 (2014)