Chapter 3
Study of Electrophysical Characteristics
of Blood Formed Elements Using
Intracavity Laser Spectroscopy
Abstract We study optical characteristics of an ensemble of arbitrarily oriented
particles are studied in an optical cavity. The study is based on the self-consistent
conjugation with respect to nonuniform optical cavities with the results of scattering
by an ensemble of arbitrarily oriented spherical particles with different shapes and
structures. A new electrodynamic model for the interaction of laser radiation with
blood cells is constructed with allowance for the structure of cells for the prediction
of optical properties in vivo and for study the polarization characteristics, absorption
curves for an ensemble of spherical particles with a nonconcentric inclusion that
are placed in a resonator cavity. Quantitative estimates are made that can be used
to predict how biophysical and biochemical processes in a biological tissue may
influence its optical properties.
3.1 Introduction
There has been considerable recent interest in the application of laser methods in
various branches of science and technology including physics, chemistry, biology,
and medicine. Laser sources are employed in medicine for diagnostics, therapy, and
surgery. Informative parameters that characterize vital activity are primarily chosen in such problems. Note the important analysis of peripheral blood, which flows
in organs and tissues, since the corresponding results can be used to characterize
a living organism. A comprehensive analysis of the parameters of light scattering
and absorption allows rapid intact determination of physiological and morphological modifications in cells due to temperature, chemical, etc., effects. It is known that
blood consists of the following blood cells: leucocytes, erythrocytes, and thrombocytes [1, 2]. The study of the optical properties of such biological objects makes
it possible to solve several important problems in diagnostics of pathologies. To
develop a mathematical model of the interaction of laser radiation with complicated
blood cells, we must consider the corresponding geometrical structures.
© Springer International Publishing AG, part of Springer Nature 2018
K. Kulikov and T. Koshlan, Laser Interaction with Heterogeneous
Biological Tissue, Biological and Medical Physics, Biomedical Engineering,
https://doi.org/10.1007/978-3-319-94114-1_3
27
Study of Electrophysical Characteristics
of Blood Formed Elements Using
Intracavity Laser Spectroscopy
Abstract We study optical characteristics of an ensemble of arbitrarily oriented
particles are studied in an optical cavity. The study is based on the self-consistent
conjugation with respect to nonuniform optical cavities with the results of scattering
by an ensemble of arbitrarily oriented spherical particles with different shapes and
structures. A new electrodynamic model for the interaction of laser radiation with
blood cells is constructed with allowance for the structure of cells for the prediction
of optical properties in vivo and for study the polarization characteristics, absorption
curves for an ensemble of spherical particles with a nonconcentric inclusion that
are placed in a resonator cavity. Quantitative estimates are made that can be used
to predict how biophysical and biochemical processes in a biological tissue may
influence its optical properties.
3.1 Introduction
There has been considerable recent interest in the application of laser methods in
various branches of science and technology including physics, chemistry, biology,
and medicine. Laser sources are employed in medicine for diagnostics, therapy, and
surgery. Informative parameters that characterize vital activity are primarily chosen in such problems. Note the important analysis of peripheral blood, which flows
in organs and tissues, since the corresponding results can be used to characterize
a living organism. A comprehensive analysis of the parameters of light scattering
and absorption allows rapid intact determination of physiological and morphological modifications in cells due to temperature, chemical, etc., effects. It is known that
blood consists of the following blood cells: leucocytes, erythrocytes, and thrombocytes [1, 2]. The study of the optical properties of such biological objects makes
it possible to solve several important problems in diagnostics of pathologies. To
develop a mathematical model of the interaction of laser radiation with complicated
blood cells, we must consider the corresponding geometrical structures.
© Springer International Publishing AG, part of Springer Nature 2018
K. Kulikov and T. Koshlan, Laser Interaction with Heterogeneous
Biological Tissue, Biological and Medical Physics, Biomedical Engineering,
https://doi.org/10.1007/978-3-319-94114-1_3
27