170
10 Study of the Optical Characteristics of Thin Layer of the Biological Sample
the biological sample in the ultraviolet range is large, while the absorption coefficient
in the visible range decreases and remains almost unchanged.
Thus, the model constructed here makes it possible to analyze the biophysical
characteristics associated with absorption of light in optically thin layers on account
of small-scale inhomogeneities. This also makes it possible to vary (on the same
setup) the biological objects and their electrophysical parameters, as well as characteristic thicknesses of the layers and the characteristic sizes of roughnesses of the
biological structure to determine the dependence between these parameters. Using
this approach systematically, it will probably be possible to find correlations between
electrophysical parameters of the biological structure being simulated and its biological properties.
It should be noted that by varying the absorption coefficient of the biological
tissue, one can use this model for in vitro measurements of the spectral characteristic
of the biological tissue taking into account small-scale inhomogeneities to construct
the spectral autograph for determining pathological changes in the biological samples
under investigation.
Analogous dependences can be calculated for lasers with other parameters and
used for processing of experimental absorption curves for biological structures under
investigation taking into account small-scale inhomogeneities.
References
1. K.G. Kulikov, Control of the optical characteristics of an optically thin layer with a rough
surface by intracavity laser spectroscopy, in European Conferences on Biomedical Optics,
22–26 May 2011, Munich, Germany (2011)
2. K.G. Kulikov, Accounting for small-scale inhomogeneities in the simulation of electrophysical characteristics of an optically thin layer method intracavity laser spectroscopy, in SPIE
Photonics Europe, 16–19 April 2012 Brussels, Belgium (2012)
3. S.M. Rytov, Yu.A. Kravtsov, V.I. Tatarskii, Introduction to Statistical Radiophysics. Part II.
Moscow (1978), 463 p
10 Study of the Optical Characteristics of Thin Layer of the Biological Sample
the biological sample in the ultraviolet range is large, while the absorption coefficient
in the visible range decreases and remains almost unchanged.
Thus, the model constructed here makes it possible to analyze the biophysical
characteristics associated with absorption of light in optically thin layers on account
of small-scale inhomogeneities. This also makes it possible to vary (on the same
setup) the biological objects and their electrophysical parameters, as well as characteristic thicknesses of the layers and the characteristic sizes of roughnesses of the
biological structure to determine the dependence between these parameters. Using
this approach systematically, it will probably be possible to find correlations between
electrophysical parameters of the biological structure being simulated and its biological properties.
It should be noted that by varying the absorption coefficient of the biological
tissue, one can use this model for in vitro measurements of the spectral characteristic
of the biological tissue taking into account small-scale inhomogeneities to construct
the spectral autograph for determining pathological changes in the biological samples
under investigation.
Analogous dependences can be calculated for lasers with other parameters and
used for processing of experimental absorption curves for biological structures under
investigation taking into account small-scale inhomogeneities.
References
1. K.G. Kulikov, Control of the optical characteristics of an optically thin layer with a rough
surface by intracavity laser spectroscopy, in European Conferences on Biomedical Optics,
22–26 May 2011, Munich, Germany (2011)
2. K.G. Kulikov, Accounting for small-scale inhomogeneities in the simulation of electrophysical characteristics of an optically thin layer method intracavity laser spectroscopy, in SPIE
Photonics Europe, 16–19 April 2012 Brussels, Belgium (2012)
3. S.M. Rytov, Yu.A. Kravtsov, V.I. Tatarskii, Introduction to Statistical Radiophysics. Part II.
Moscow (1978), 463 p