46. H.J. Seo, S.H. Nam, H.J. Im, J.Y. Park, J.Y. Lee, B. Yoo et al., Rapid hepatobiliary excretion
of micelle-encapsulated/radiolabeled upconverting nanoparticles as an integrated form. Sci.
Rep. 5, 15685 (2015)
47. S. Jeong, Y.I. Kim, H. Kang, G. Kim, M.G. Cha, H. Chang et al., Fluorescence-Raman dual
modal endoscopic system for multiplexed molecular diagnostics. Sci. Rep. 5, 9455 (2015)
48. Y.I. Kim, S. Jeong, K.O. Jung, M.G. Song, C.H. Lee, S.J. Chung et al., Simultaneous
detection of EGFR and VEGF in colorectal cancer using fluorescence-Raman endoscopy. Sci.
Rep. 7(1), 1035 (2017)
49. L. Zhang, Z. Cao, T. Bai, L. Carr, J.R. Ella-Menye, C. Irvin, B.D. Ratner, S. Jiang,
Zwitterionic hydrogels implanted in mice resist the foreign-body reaction. Nat. Biotechnol. 31
(6), 553–556 (2013)
50. W. Yang, J.R. Ella-Menye, S. Liu, T. Bai, D. Wang, Q. Yu, Y. Li, S. Jiang, Cross-linked
carboxybetaine SAMs enable nanoparticles with remarkable stability in complex media.
Langmuir 30(9), 2522–2529 (2014)
51. D. Kim, M.K. Chae, H.J. Joo, I.H. Jeong, J.H. Cho, C. Lee, Facile preparation of
zwitterion-stabilized superparamagnetic iron oxide nanoparticles (ZSPIONs) as an MR
contrast agent for in vivo applications. Langmuir 28(25), 9634–9639 (2012)
52. Z. Zhou, L. Wang, X. Chi, J. Bao, L. Yang, W. Zhao et al., Engineered iron-oxide-based
nanoparticles as enhanced T1 contrast agents for efficient tumor imaging. ACS Nano 7(4),
3287–3296 (2013)
53. F. Hu, K. Chen, H. Xu, H. Gu, Functional short-chain zwitterion coated silica nanoparticles
with antifouling property in protein solutions. Coll. Surf. B Biointerfaces 126, 251–256
(2015)
54. H. Wei, O.T. Bruns, M.G. Kaul, E.C. Hansen, M. Barch, A. Wiśniowska et al., Exceedingly
small iron oxide nanoparticles as positive MRI contrast agents. Proc. Natl. Acad. Sci. U S A.
114(9), 2325–2330 (2017)
55. F. Xu, M. Reiser, X. Yu, S. Gummuluru, L. Wetzler, B.M. Reinhard, Lipid-mediated
targeting with membrane-wrapped nanoparticles in the presence of corona formation. ACS
Nano 10(1), 1189–1200 (2016)
56. B. Dubertret, P. Skourides, D.J. Norris, V. Noireaux, A.H. Brivanlou, A. Libchaber, In vivo
imaging of quantum dots encapsulated in phospholipid micelles. Science 298(5599), 1759–
1762 (2002)
57. H. Fan, K. Yang, D.M. Boye, T. Sigmon, K.J. Malloy, H. Xu et al., Self-assembly of ordered,
robust, three-dimensional gold nanocrystal/silica arrays. Science 304(5670), 567–571 (2004)
58. H. Fan, E.W. Leve, C. Scullin, J. Gabaldon, D. Tallant, S. Bunge et al., Surfactant-assisted
synthesis of water-soluble and biocompatible semiconductor quantum dot micelles. Nano
Lett. 5(4), 645–648 (2005)
59. O. Carion, B. Mahler, T. Pons, B. Dubertret, Synthesis, encapsulation, purification and
coupling of single quantum dots in phospholipid micelles for their use in cellular and in vivo
imaging. Nat. Protoc. 2(10), 2383–2390 (2007)
60. D.S. Lee, H.J. Im, Y.S. Lee, Radionanomedicine: widened perspectives of molecular
theragnosis. Nanomedicine 11(4), 795–810 (2015)
61. K. Stockhofe, J.M. Postema, H. Schieferstein, T.L. Ross, Radiolabeling of nanoparticles and
polymers for PET imaging. Pharmaceuticals 7(4), 392–418 (2014)
18 Polyethylene Glycolation (PEGylation) and the Similar
345
of micelle-encapsulated/radiolabeled upconverting nanoparticles as an integrated form. Sci.
Rep. 5, 15685 (2015)
47. S. Jeong, Y.I. Kim, H. Kang, G. Kim, M.G. Cha, H. Chang et al., Fluorescence-Raman dual
modal endoscopic system for multiplexed molecular diagnostics. Sci. Rep. 5, 9455 (2015)
48. Y.I. Kim, S. Jeong, K.O. Jung, M.G. Song, C.H. Lee, S.J. Chung et al., Simultaneous
detection of EGFR and VEGF in colorectal cancer using fluorescence-Raman endoscopy. Sci.
Rep. 7(1), 1035 (2017)
49. L. Zhang, Z. Cao, T. Bai, L. Carr, J.R. Ella-Menye, C. Irvin, B.D. Ratner, S. Jiang,
Zwitterionic hydrogels implanted in mice resist the foreign-body reaction. Nat. Biotechnol. 31
(6), 553–556 (2013)
50. W. Yang, J.R. Ella-Menye, S. Liu, T. Bai, D. Wang, Q. Yu, Y. Li, S. Jiang, Cross-linked
carboxybetaine SAMs enable nanoparticles with remarkable stability in complex media.
Langmuir 30(9), 2522–2529 (2014)
51. D. Kim, M.K. Chae, H.J. Joo, I.H. Jeong, J.H. Cho, C. Lee, Facile preparation of
zwitterion-stabilized superparamagnetic iron oxide nanoparticles (ZSPIONs) as an MR
contrast agent for in vivo applications. Langmuir 28(25), 9634–9639 (2012)
52. Z. Zhou, L. Wang, X. Chi, J. Bao, L. Yang, W. Zhao et al., Engineered iron-oxide-based
nanoparticles as enhanced T1 contrast agents for efficient tumor imaging. ACS Nano 7(4),
3287–3296 (2013)
53. F. Hu, K. Chen, H. Xu, H. Gu, Functional short-chain zwitterion coated silica nanoparticles
with antifouling property in protein solutions. Coll. Surf. B Biointerfaces 126, 251–256
(2015)
54. H. Wei, O.T. Bruns, M.G. Kaul, E.C. Hansen, M. Barch, A. Wiśniowska et al., Exceedingly
small iron oxide nanoparticles as positive MRI contrast agents. Proc. Natl. Acad. Sci. U S A.
114(9), 2325–2330 (2017)
55. F. Xu, M. Reiser, X. Yu, S. Gummuluru, L. Wetzler, B.M. Reinhard, Lipid-mediated
targeting with membrane-wrapped nanoparticles in the presence of corona formation. ACS
Nano 10(1), 1189–1200 (2016)
56. B. Dubertret, P. Skourides, D.J. Norris, V. Noireaux, A.H. Brivanlou, A. Libchaber, In vivo
imaging of quantum dots encapsulated in phospholipid micelles. Science 298(5599), 1759–
1762 (2002)
57. H. Fan, K. Yang, D.M. Boye, T. Sigmon, K.J. Malloy, H. Xu et al., Self-assembly of ordered,
robust, three-dimensional gold nanocrystal/silica arrays. Science 304(5670), 567–571 (2004)
58. H. Fan, E.W. Leve, C. Scullin, J. Gabaldon, D. Tallant, S. Bunge et al., Surfactant-assisted
synthesis of water-soluble and biocompatible semiconductor quantum dot micelles. Nano
Lett. 5(4), 645–648 (2005)
59. O. Carion, B. Mahler, T. Pons, B. Dubertret, Synthesis, encapsulation, purification and
coupling of single quantum dots in phospholipid micelles for their use in cellular and in vivo
imaging. Nat. Protoc. 2(10), 2383–2390 (2007)
60. D.S. Lee, H.J. Im, Y.S. Lee, Radionanomedicine: widened perspectives of molecular
theragnosis. Nanomedicine 11(4), 795–810 (2015)
61. K. Stockhofe, J.M. Postema, H. Schieferstein, T.L. Ross, Radiolabeling of nanoparticles and
polymers for PET imaging. Pharmaceuticals 7(4), 392–418 (2014)
18 Polyethylene Glycolation (PEGylation) and the Similar
345
