21. X.F. He, M.H. Na, J.S. Kim, G.Y. Lee, J.Y. Park, A.S. Hoffman et al., A novel peptide probe
for imaging and targeted delivery of liposomal doxorubicin to lung tumor. Mol. Pharmaceut.
8(2), 430–438 (2011)
22. E.A. Murphy, B.K. Majeti, L.A. Barnes, M. Makale, S.M. Weis, K. Lutu-Fuga et al.,
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proc. Natl.
Acad. Sci. U.S.A. 105(27), 9343–9348 (2008)
23. H.Y. Lee, Z. Li, K. Chen, A.R. Hsu, C.J. Xu, J. Xie et al., PET/MRI dual-modality tumor
imaging using arginine-glycine-aspartic (RGD)—conjugated radiolabeled iron oxide nanoparticles. J. Nucl. Med. 49(8), 1371–1379 (2008)
24. D. Arosio, L. Manzoni, E.M.V. Araldi, C. Scolastico, Cyclic RGD functionalized gold
nanoparticles for tumor targeting. Bioconjug. Chem. 22(4), 664–672 (2011)
25. D.R. Vera, A.M. Wallace, C.K. Hoh, R.F. Mattrey, A synthetic macromolecule for sentinel
node detection: Tc-99 m-DTPA-mannosyl-dextran. J. Nucl. Med. 42(6), 951–959 (2001)
26. J.M. Jeong, M.K. Hong, Y.J. Kim, J. Lee, J.H. Kang, D.S. Lee et al., Development of
Tc-99 m-neomannosyl human serum albumin (Tc-99 m-MSA) as a novel receptor binding
agent for sentinel lymph node imaging. Nucl. Med. Commun. 25(12), 1211–1217 (2004)
27. S.P. Lee, H.J. Im, S. Kang, S.J. Chung, Y.S. Cho, H. Kang et al., Noninvasive imaging of
myocardial inflammation in myocarditis using Ga-68-tagged mannosylated human serum
albumin positron emission tomography. Theranostics 7(2), 413–424 (2017)
28. Z.Y. Shen, W. Wei, H. Tanaka, K. Kohama, G.H. Ma, T. Dobashi et al., A
galactosamine-mediated drug delivery carrier for targeted liver cancer therapy. Pharmacol.
Res. 64(4), 410–419 (2011)
29. E.M. Kim, H.J. Jeong, I.K. Park, C.S. Cho, H.B. Moon, D.Y. Yu et al., Asialoglycoprotein
receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene
glycol): in vitro and in vivo studies. J. Control Release 108(2–3), 557–567 (2005)
30. C.M. Lee, H.J. Jeong, E.M. Kim, D.W. Kim, S.T. Lim, H.T. Kim et al., Superparamagnetic
iron oxide nanoparticles as a dual imaging probe for targeting hepatocytes in vivo. Magn.
Reson. Med. 62(6), 1440–1446 (2009)
31. H.S. Yoo, T.G. Park, Folate-receptor-targeted delivery of doxorubicin nano-aggregates
stabilized by doxorubicin-PEG-folate conjugate. J. Control Release 100(2), 247–256 (2004)
32. J. Lu, M. Liong, Z.X. Li, J.I. Zink, F. Tamanoi, Biocompatibility, biodistribution, and
drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals.
Small 6(16), 1794–1805 (2010)
33. T. Maurer, M. Eiber, M. Schwaiger, J.E. Gschwend, Current use of PSMA—PET in prostate
cancer management. Nat. Rev. Urol. 13(4), 226–235 (2016)
34. M. Eder, M. Schafer, U. Bauder-Wust, W.E. Hull, C. Wangler, W. Mier et al., Ga-68-complex
lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging.
Bioconjug. Chem. 23(4), 688–697 (2012)
35. S.S. Chandran, S.R. Banerjee, R.C. Mease, M.G. Pomper, S.R. Denmeade, Characterization
of a targeted nanoparticle functionalized with a urea-based inhibitor of prostate-specific
membrane antigen (PSMA). Cancer Biol. Ther. 7(6), 978–986 (2008)
36. D.D. Von Hoff, M.M. Mita, R.K. Ramanathan, G.J. Weiss, A.C. Mita, P.M. LoRusso et al.,
Phase I study of PSMA-targeted docetaxel-containing nanoparticle BIND-014 in patients with
advanced solid tumors. Clin. Cancer Res. 22(13), 3157–3163 (2016)
37. C.G. Hadjipanayis, R. Machaidze, M. Kaluzova, L. Wang, A.J. Schuette, H. Chen et al.,
EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance
imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma. Cancer
Res. 70(15), 6303–6312 (2010)
38. Y. Ling, K. Wei, Y. Luo, X. Gao, S.Z. Zhong, Dual docetaxel/superparamagnetic iron oxide
loaded nanoparticles for both targeting magnetic resonance imaging and cancer therapy.
Biomaterials 32(29), 7139–7150 (2011)
39. G.H. Chen, W.J. Chen, Z. Wu, R.X. Yuan, H. Li, J.M. Gao et al., MRI-visible polymeric
vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression.
Biomaterials 30(10), 1962–1970 (2009)
248
Y.-S. Lee et al.
for imaging and targeted delivery of liposomal doxorubicin to lung tumor. Mol. Pharmaceut.
8(2), 430–438 (2011)
22. E.A. Murphy, B.K. Majeti, L.A. Barnes, M. Makale, S.M. Weis, K. Lutu-Fuga et al.,
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis. Proc. Natl.
Acad. Sci. U.S.A. 105(27), 9343–9348 (2008)
23. H.Y. Lee, Z. Li, K. Chen, A.R. Hsu, C.J. Xu, J. Xie et al., PET/MRI dual-modality tumor
imaging using arginine-glycine-aspartic (RGD)—conjugated radiolabeled iron oxide nanoparticles. J. Nucl. Med. 49(8), 1371–1379 (2008)
24. D. Arosio, L. Manzoni, E.M.V. Araldi, C. Scolastico, Cyclic RGD functionalized gold
nanoparticles for tumor targeting. Bioconjug. Chem. 22(4), 664–672 (2011)
25. D.R. Vera, A.M. Wallace, C.K. Hoh, R.F. Mattrey, A synthetic macromolecule for sentinel
node detection: Tc-99 m-DTPA-mannosyl-dextran. J. Nucl. Med. 42(6), 951–959 (2001)
26. J.M. Jeong, M.K. Hong, Y.J. Kim, J. Lee, J.H. Kang, D.S. Lee et al., Development of
Tc-99 m-neomannosyl human serum albumin (Tc-99 m-MSA) as a novel receptor binding
agent for sentinel lymph node imaging. Nucl. Med. Commun. 25(12), 1211–1217 (2004)
27. S.P. Lee, H.J. Im, S. Kang, S.J. Chung, Y.S. Cho, H. Kang et al., Noninvasive imaging of
myocardial inflammation in myocarditis using Ga-68-tagged mannosylated human serum
albumin positron emission tomography. Theranostics 7(2), 413–424 (2017)
28. Z.Y. Shen, W. Wei, H. Tanaka, K. Kohama, G.H. Ma, T. Dobashi et al., A
galactosamine-mediated drug delivery carrier for targeted liver cancer therapy. Pharmacol.
Res. 64(4), 410–419 (2011)
29. E.M. Kim, H.J. Jeong, I.K. Park, C.S. Cho, H.B. Moon, D.Y. Yu et al., Asialoglycoprotein
receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene
glycol): in vitro and in vivo studies. J. Control Release 108(2–3), 557–567 (2005)
30. C.M. Lee, H.J. Jeong, E.M. Kim, D.W. Kim, S.T. Lim, H.T. Kim et al., Superparamagnetic
iron oxide nanoparticles as a dual imaging probe for targeting hepatocytes in vivo. Magn.
Reson. Med. 62(6), 1440–1446 (2009)
31. H.S. Yoo, T.G. Park, Folate-receptor-targeted delivery of doxorubicin nano-aggregates
stabilized by doxorubicin-PEG-folate conjugate. J. Control Release 100(2), 247–256 (2004)
32. J. Lu, M. Liong, Z.X. Li, J.I. Zink, F. Tamanoi, Biocompatibility, biodistribution, and
drug-delivery efficiency of mesoporous silica nanoparticles for cancer therapy in animals.
Small 6(16), 1794–1805 (2010)
33. T. Maurer, M. Eiber, M. Schwaiger, J.E. Gschwend, Current use of PSMA—PET in prostate
cancer management. Nat. Rev. Urol. 13(4), 226–235 (2016)
34. M. Eder, M. Schafer, U. Bauder-Wust, W.E. Hull, C. Wangler, W. Mier et al., Ga-68-complex
lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging.
Bioconjug. Chem. 23(4), 688–697 (2012)
35. S.S. Chandran, S.R. Banerjee, R.C. Mease, M.G. Pomper, S.R. Denmeade, Characterization
of a targeted nanoparticle functionalized with a urea-based inhibitor of prostate-specific
membrane antigen (PSMA). Cancer Biol. Ther. 7(6), 978–986 (2008)
36. D.D. Von Hoff, M.M. Mita, R.K. Ramanathan, G.J. Weiss, A.C. Mita, P.M. LoRusso et al.,
Phase I study of PSMA-targeted docetaxel-containing nanoparticle BIND-014 in patients with
advanced solid tumors. Clin. Cancer Res. 22(13), 3157–3163 (2016)
37. C.G. Hadjipanayis, R. Machaidze, M. Kaluzova, L. Wang, A.J. Schuette, H. Chen et al.,
EGFRvIII antibody-conjugated iron oxide nanoparticles for magnetic resonance
imaging-guided convection-enhanced delivery and targeted therapy of glioblastoma. Cancer
Res. 70(15), 6303–6312 (2010)
38. Y. Ling, K. Wei, Y. Luo, X. Gao, S.Z. Zhong, Dual docetaxel/superparamagnetic iron oxide
loaded nanoparticles for both targeting magnetic resonance imaging and cancer therapy.
Biomaterials 32(29), 7139–7150 (2011)
39. G.H. Chen, W.J. Chen, Z. Wu, R.X. Yuan, H. Li, J.M. Gao et al., MRI-visible polymeric
vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression.
Biomaterials 30(10), 1962–1970 (2009)
248
Y.-S. Lee et al.