14. M.K. Khan, L.D. Minc, S.S. Nigavekar, M.S. Kariapper, B.M. Nair, M. Schipper et al.,
Fabrication of
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Au radioactive composite nanodevices and their use for nanobrachytherapy. Nanomed. (Lond.) 4(1), 57–69 (2008)
15. R. Shukla, N. Chanda, A. Zambre, A. Upendran, K. Katti, R.R. Kulkarni et al., Laminin
receptor specific therapeutic gold nanoparticles (
198
AuNP-EGCg) show efficacy in treating
prostate cancer. Proc. Natl. Acad. Sci. U S A 109(31), 12426–12431 (2012)
16. C. Zhou, G. Hao, P. Thomas, J. Liu, M. Yu, S. Sun et al., Near-infrared emitting radioactive
gold nanoparticles with molecular pharmacokinetics. Angew. Chem. Int. Ed. Engl. 51(40),
10118–10122 (2012)
17. Y. Wang, Y. Liu, H. Luehmann, X. Xia, D. Wan, C. Cutler et al., Radioluminescent gold
nanocages with controlled radioactivity for real-time in vivo imaging. Nano Lett. 13(2),
581–585 (2013)
18. Y. Sun, X. Zhu, J. Peng, F. Li, Core-shell lanthanide upconversion nanophosphors as
four-modal probes for tumor angiogenesis imaging. ACS Nano 7(12), 11290–11300 (2013)
19. Y. Yang, Y. Sun, T. Cao, J. Peng, Y. Liu, Y. Wu et al., Hydrothermal synthesis of
NaLuF4:153Sm, Yb, Tm nanoparticles and their application in dual-modality upconversion
luminescence and SPECT bioimaging. Biomaterials 34(3), 774–783 (2013)
20. J. Zeng, B. Jia, R. Qiao, C. Wang, L. Jing, F. Wang et al., In situ 111In-doping for achieving
biocompatible and non-leachable
111
In-labeled Fe3O4 nanoparticles. Chem. Commun.
(Camb.) 50(17), 2170–2172 (2014)
21. Q. Liu, Y. Sun, C. Li, J. Zhou, T. Yang, X. Zhang et al.,
18
F-Labeled magnetic-upconversion
nanophosphors via rare-Earth cation-assisted ligand assembly. ACS Nano 5(4), 3146–3157
(2011)
22. Y. Sun, M. Yu, S. Liang, Y. Zhang, C. Li, T. Mou et al., Fluorine-18 labeled rare-earth
nanoparticles for positron emission tomography (PET) imaging of sentinel lymph node.
Biomaterials 32(11), 2999–3007 (2011)
23. F. Chen, P.A. Ellison, C.M. Lewis, H. Hong, Y. Zhang, S. Shi et al., Chelator-free synthesis
of a dual-modality PET/MRI agent. Angew. Chem. Int. Ed. Engl. 52(50), 13319–13323
(2013)
24. R. Chakravarty, H.F. Valdovinos, F. Chen, C.M. Lewis, P.A. Ellison, H. Luo et al.,
Intrinsically germanium-69-labeled iron oxide nanoparticles: synthesis and in-vivo
dual-modality PET/MR imaging. Adv. Mater. 26(30), 5119–5123 (2014)
25. A.N. Mendoza-Sanchez, G. Ferro-Flores, B.E. Ocampo-Garcia, E. Morales-Avila, F. de M
Ramírez, L.M. De Leon-Rodriguez et al., Lys3-bombesin conjugated to
99m
Tc-labeled gold
nanoparticles for in vivo gastrin releasing peptide-receptor imaging. J. Biomed.
Nanotechnol. 6(4), 375–384 (2010)
26. E. Morales-Avila, G. Ferro-Flores, B.E. Ocampo-Garcia, L.M. De Leon-Rodriguez, C.L.
Santos-Cuevas, R. Garcia-Becerra et al., Multimeric system of
99m Tc-labeled gold
nanoparticles conjugated to c[RGDfK(C)] for molecular imaging of tumor alpha(v)beta(3)
expression. Bioconjug. Chem. 22(5), 913–922 (2011)
27. B.E. Ocampo-Garcia, M. Ramirez Fde, G. Ferro-Flores, L.M. De Leon-Rodriguez, C.L.
Santos-Cuevas, E. Morales-Avila et al.,
99m
Tc-labeled gold nanoparticles capped with
HYNIC-peptide/mannose for sentinel lymph node detection. Nucl. Med. Biol. 38(1), 1–11
(2011)
28. G. Zhang, Z. Yang, W. Lu, R. Zhang, Q. Huang, M. Tian et al., Influence of anchoring
ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene
glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials 30(10), 1928–
1936 (2009)
29. R. Torres Martin de Rosales R, R. Tavare, A. Glaria, G. Varma, A. Protti, P.J. Blower,
99m
Tc-bisphosphonate-iron oxide nanoparticle conjugates for dual-modality biomedical
imaging. Bioconjug. Chem. 22(3), 455–465 (2011)
30. W. Cai, K. Chen, Z.B. Li, S.S. Gambhir, X. Chen, Dual-function probe for PET and
near-infrared fluorescence imaging of tumor vasculature. J. Nucl. Med. 48(11), 1862–1870
(2007)
11 Radiolabeling Method: Core/Surface Labeling, Chemical …
223
Fabrication of
198
Au radioactive composite nanodevices and their use for nanobrachytherapy. Nanomed. (Lond.) 4(1), 57–69 (2008)
15. R. Shukla, N. Chanda, A. Zambre, A. Upendran, K. Katti, R.R. Kulkarni et al., Laminin
receptor specific therapeutic gold nanoparticles (
198
AuNP-EGCg) show efficacy in treating
prostate cancer. Proc. Natl. Acad. Sci. U S A 109(31), 12426–12431 (2012)
16. C. Zhou, G. Hao, P. Thomas, J. Liu, M. Yu, S. Sun et al., Near-infrared emitting radioactive
gold nanoparticles with molecular pharmacokinetics. Angew. Chem. Int. Ed. Engl. 51(40),
10118–10122 (2012)
17. Y. Wang, Y. Liu, H. Luehmann, X. Xia, D. Wan, C. Cutler et al., Radioluminescent gold
nanocages with controlled radioactivity for real-time in vivo imaging. Nano Lett. 13(2),
581–585 (2013)
18. Y. Sun, X. Zhu, J. Peng, F. Li, Core-shell lanthanide upconversion nanophosphors as
four-modal probes for tumor angiogenesis imaging. ACS Nano 7(12), 11290–11300 (2013)
19. Y. Yang, Y. Sun, T. Cao, J. Peng, Y. Liu, Y. Wu et al., Hydrothermal synthesis of
NaLuF4:153Sm, Yb, Tm nanoparticles and their application in dual-modality upconversion
luminescence and SPECT bioimaging. Biomaterials 34(3), 774–783 (2013)
20. J. Zeng, B. Jia, R. Qiao, C. Wang, L. Jing, F. Wang et al., In situ 111In-doping for achieving
biocompatible and non-leachable
111
In-labeled Fe3O4 nanoparticles. Chem. Commun.
(Camb.) 50(17), 2170–2172 (2014)
21. Q. Liu, Y. Sun, C. Li, J. Zhou, T. Yang, X. Zhang et al.,
18
F-Labeled magnetic-upconversion
nanophosphors via rare-Earth cation-assisted ligand assembly. ACS Nano 5(4), 3146–3157
(2011)
22. Y. Sun, M. Yu, S. Liang, Y. Zhang, C. Li, T. Mou et al., Fluorine-18 labeled rare-earth
nanoparticles for positron emission tomography (PET) imaging of sentinel lymph node.
Biomaterials 32(11), 2999–3007 (2011)
23. F. Chen, P.A. Ellison, C.M. Lewis, H. Hong, Y. Zhang, S. Shi et al., Chelator-free synthesis
of a dual-modality PET/MRI agent. Angew. Chem. Int. Ed. Engl. 52(50), 13319–13323
(2013)
24. R. Chakravarty, H.F. Valdovinos, F. Chen, C.M. Lewis, P.A. Ellison, H. Luo et al.,
Intrinsically germanium-69-labeled iron oxide nanoparticles: synthesis and in-vivo
dual-modality PET/MR imaging. Adv. Mater. 26(30), 5119–5123 (2014)
25. A.N. Mendoza-Sanchez, G. Ferro-Flores, B.E. Ocampo-Garcia, E. Morales-Avila, F. de M
Ramírez, L.M. De Leon-Rodriguez et al., Lys3-bombesin conjugated to
99m
Tc-labeled gold
nanoparticles for in vivo gastrin releasing peptide-receptor imaging. J. Biomed.
Nanotechnol. 6(4), 375–384 (2010)
26. E. Morales-Avila, G. Ferro-Flores, B.E. Ocampo-Garcia, L.M. De Leon-Rodriguez, C.L.
Santos-Cuevas, R. Garcia-Becerra et al., Multimeric system of
99m Tc-labeled gold
nanoparticles conjugated to c[RGDfK(C)] for molecular imaging of tumor alpha(v)beta(3)
expression. Bioconjug. Chem. 22(5), 913–922 (2011)
27. B.E. Ocampo-Garcia, M. Ramirez Fde, G. Ferro-Flores, L.M. De Leon-Rodriguez, C.L.
Santos-Cuevas, E. Morales-Avila et al.,
99m
Tc-labeled gold nanoparticles capped with
HYNIC-peptide/mannose for sentinel lymph node detection. Nucl. Med. Biol. 38(1), 1–11
(2011)
28. G. Zhang, Z. Yang, W. Lu, R. Zhang, Q. Huang, M. Tian et al., Influence of anchoring
ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene
glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials 30(10), 1928–
1936 (2009)
29. R. Torres Martin de Rosales R, R. Tavare, A. Glaria, G. Varma, A. Protti, P.J. Blower,
99m
Tc-bisphosphonate-iron oxide nanoparticle conjugates for dual-modality biomedical
imaging. Bioconjug. Chem. 22(3), 455–465 (2011)
30. W. Cai, K. Chen, Z.B. Li, S.S. Gambhir, X. Chen, Dual-function probe for PET and
near-infrared fluorescence imaging of tumor vasculature. J. Nucl. Med. 48(11), 1862–1870
(2007)
11 Radiolabeling Method: Core/Surface Labeling, Chemical …
223