72. S. Shi, F. Chen, E.B. Ehlerding, W. Cai, Surface engineering of graphene-based
nanomaterials for biomedical applications. Bioconjug. Chem. 25(9), 1609–1619 (2014)
73. H. Hong, Y. Zhang, J.W. Engle, T.R. Nayak, C.P. Theuer, R.J. Nickles et al., In vivo
targeting and positron emission tomography imaging of tumor vasculature with
66
Ga-labeled
nano-graphene. Biomaterials 33(16), 4147–4156 (2012)
74. H. Hong, K. Yang, Y. Zhang, J.W. Engle, L. Feng, Y. Yang et al., In vivo targeting and
imaging of tumor vasculature with radiolabeled, antibody-conjugated nanographene. ACS
Nano 6(3), 2361–2370 (2012)
75. D. Yang, L. Feng, C.A. Dougherty, K.E. Luker, D. Chen, M.A. Cauble et al., In vivo
targeting of metastatic breast cancer via tumor vasculature-specific nano-graphene oxide.
Biomaterials 104, 361–371 (2016)
76. B. Cornelissen, S. Able, V. Kersemans, P.A. Waghorn, S. Myhra, K. Jurkshat et al.,
Nanographene oxide-based radioimmunoconstructs for in vivo targeting and SPECT
imaging of HER2-positive tumors. Biomaterials 34(4), 1146–1154 (2013)
77. S. Shi, C. Xu, K. Yang, S. Goel, H.F. Valdovinos, H. Luo et al., Chelator-free radiolabeling
of nanographene: breaking the stereotype of chelation. Angew. Chem. Int. Ed. Engl. 56(11),
2889–2892 (2017)
78. S. Shi, K. Yang, H. Hong, H.F. Valdovinos, T.R. Nayak, Y. Zhang et al., Tumor vasculature
targeting and imaging in living mice with reduced graphene oxide. Biomaterials 34(12),
3002–3009 (2013)
79. C. Xu, S. Shi, L. Feng, F. Chen, S.A. Graves, E.B. Ehlerding et al., Long circulating reduced
graphene oxide-iron oxide nanoparticles for efficient tumor targeting and multimodality
imaging. Nanoscale 8(25), 12683–12692 (2016)
80. S. Same, A. Aghanejad, S. Akbari Nakhjavani, J. Barar, Y. Omidi, Radiolabeled
theranostics: magnetic and gold nanoparticles. BioImpacts 6(3), 169–181 (2016)
81. H. Hong, F. Chen, W. Cai, Pharmacokinetic issues of imaging with nanoparticles: focusing
on carbon nanotubes and quantum dots. Mol. Imaging Biol. 15(5), 507–520 (2013)
82. Y.I. Park, K.T. Lee, Y.D. Suh, T. Hyeon, Upconverting nanoparticles: a versatile platform
for wide-field two-photon microscopy and multi-modal in vivo imaging. Chem. Soc. Rev.
44(6), 1302–1317 (2015)
83. Y. Zhang, T.R. Nayak, H. Hong, W. Cai, Biomedical applications of zinc oxide
nanomaterials. Cur Mol Med. 13(10), 1633–1645 (2013)
84. F. Chen, S. Goel, R. Hernandez, S.A. Graves, S. Shi, R.J. Nickles et al., Dynamic positron
emission tomography imaging of renal clearable gold nanoparticles. Small 12(20), 2775–
2782 (2016)
85. M. Felber, M. Bauwens, J.M. Mateos, S. Imstepf, F.M. Mottaghy, R. Alberto,
99m
Tc
radiolabeling and biological evaluation of nanoparticles functionalized with a versatile
coating ligand. Chemistry 21(16), 6090–6099 (2015)
86. J. Lee, T.S. Lee, J. Ryu, S. Hong, M. Kang, K. Im et al., RGD peptide-conjugated
multimodal NaGdF 4 :Yb
3+ /Er
3+ nanophosphors for upconversion luminescence, MR, and
PET imaging of tumor angiogenesis. J. Nucl. Med. 54(1), 96–103 (2013)
87. J. Peng, Y. Sun, L. Zhao, Y. Wu, W. Feng, Y. Gao et al., Polyphosphoric acid capping
radioactive/upconverting NaLuF4: Yb, Tm, 153Sm nanoparticles for blood pool imaging
in vivo. Biomaterials 34(37), 9535–9544 (2013)
88. A.A. Bogdanov Jr., S. Gupta, N. Koshkina, S.J. Corr, S. Zhang, S.A. Curley et al., Gold
nanoparticles stabilized with MPEG-grafted poly(l-lysine): in vitro and in vivo evaluation of
a potential theranostic agent. Bioconjug. Chem. 26(1), 39–50 (2015)
89. M. Zhou, S. Song, J. Zhao, M. Tian, C. Li, Theranostic CuS nanoparticles targeting folate
receptors for PET image-guided photothermal therapy. J Mater. Chem B 3(46), 8939–8948
(2015)
90. F. Gao, P. Cai, W. Yang, J. Xue, L. Gao, R. Liu et al., Ultrasmall [
64
Cu] Cu nanoclusters for
targeting orthotopic lung tumors using accurate positron emission tomography imaging.
ACS Nano 9(5), 4976–4986 (2015)
204
D. Chen and H. Hong
nanomaterials for biomedical applications. Bioconjug. Chem. 25(9), 1609–1619 (2014)
73. H. Hong, Y. Zhang, J.W. Engle, T.R. Nayak, C.P. Theuer, R.J. Nickles et al., In vivo
targeting and positron emission tomography imaging of tumor vasculature with
66
Ga-labeled
nano-graphene. Biomaterials 33(16), 4147–4156 (2012)
74. H. Hong, K. Yang, Y. Zhang, J.W. Engle, L. Feng, Y. Yang et al., In vivo targeting and
imaging of tumor vasculature with radiolabeled, antibody-conjugated nanographene. ACS
Nano 6(3), 2361–2370 (2012)
75. D. Yang, L. Feng, C.A. Dougherty, K.E. Luker, D. Chen, M.A. Cauble et al., In vivo
targeting of metastatic breast cancer via tumor vasculature-specific nano-graphene oxide.
Biomaterials 104, 361–371 (2016)
76. B. Cornelissen, S. Able, V. Kersemans, P.A. Waghorn, S. Myhra, K. Jurkshat et al.,
Nanographene oxide-based radioimmunoconstructs for in vivo targeting and SPECT
imaging of HER2-positive tumors. Biomaterials 34(4), 1146–1154 (2013)
77. S. Shi, C. Xu, K. Yang, S. Goel, H.F. Valdovinos, H. Luo et al., Chelator-free radiolabeling
of nanographene: breaking the stereotype of chelation. Angew. Chem. Int. Ed. Engl. 56(11),
2889–2892 (2017)
78. S. Shi, K. Yang, H. Hong, H.F. Valdovinos, T.R. Nayak, Y. Zhang et al., Tumor vasculature
targeting and imaging in living mice with reduced graphene oxide. Biomaterials 34(12),
3002–3009 (2013)
79. C. Xu, S. Shi, L. Feng, F. Chen, S.A. Graves, E.B. Ehlerding et al., Long circulating reduced
graphene oxide-iron oxide nanoparticles for efficient tumor targeting and multimodality
imaging. Nanoscale 8(25), 12683–12692 (2016)
80. S. Same, A. Aghanejad, S. Akbari Nakhjavani, J. Barar, Y. Omidi, Radiolabeled
theranostics: magnetic and gold nanoparticles. BioImpacts 6(3), 169–181 (2016)
81. H. Hong, F. Chen, W. Cai, Pharmacokinetic issues of imaging with nanoparticles: focusing
on carbon nanotubes and quantum dots. Mol. Imaging Biol. 15(5), 507–520 (2013)
82. Y.I. Park, K.T. Lee, Y.D. Suh, T. Hyeon, Upconverting nanoparticles: a versatile platform
for wide-field two-photon microscopy and multi-modal in vivo imaging. Chem. Soc. Rev.
44(6), 1302–1317 (2015)
83. Y. Zhang, T.R. Nayak, H. Hong, W. Cai, Biomedical applications of zinc oxide
nanomaterials. Cur Mol Med. 13(10), 1633–1645 (2013)
84. F. Chen, S. Goel, R. Hernandez, S.A. Graves, S. Shi, R.J. Nickles et al., Dynamic positron
emission tomography imaging of renal clearable gold nanoparticles. Small 12(20), 2775–
2782 (2016)
85. M. Felber, M. Bauwens, J.M. Mateos, S. Imstepf, F.M. Mottaghy, R. Alberto,
99m
Tc
radiolabeling and biological evaluation of nanoparticles functionalized with a versatile
coating ligand. Chemistry 21(16), 6090–6099 (2015)
86. J. Lee, T.S. Lee, J. Ryu, S. Hong, M. Kang, K. Im et al., RGD peptide-conjugated
multimodal NaGdF 4 :Yb
3+ /Er
3+ nanophosphors for upconversion luminescence, MR, and
PET imaging of tumor angiogenesis. J. Nucl. Med. 54(1), 96–103 (2013)
87. J. Peng, Y. Sun, L. Zhao, Y. Wu, W. Feng, Y. Gao et al., Polyphosphoric acid capping
radioactive/upconverting NaLuF4: Yb, Tm, 153Sm nanoparticles for blood pool imaging
in vivo. Biomaterials 34(37), 9535–9544 (2013)
88. A.A. Bogdanov Jr., S. Gupta, N. Koshkina, S.J. Corr, S. Zhang, S.A. Curley et al., Gold
nanoparticles stabilized with MPEG-grafted poly(l-lysine): in vitro and in vivo evaluation of
a potential theranostic agent. Bioconjug. Chem. 26(1), 39–50 (2015)
89. M. Zhou, S. Song, J. Zhao, M. Tian, C. Li, Theranostic CuS nanoparticles targeting folate
receptors for PET image-guided photothermal therapy. J Mater. Chem B 3(46), 8939–8948
(2015)
90. F. Gao, P. Cai, W. Yang, J. Xue, L. Gao, R. Liu et al., Ultrasmall [
64
Cu] Cu nanoclusters for
targeting orthotopic lung tumors using accurate positron emission tomography imaging.
ACS Nano 9(5), 4976–4986 (2015)
204
D. Chen and H. Hong