12. M. Neagu, Z. Piperigkou, K. Karamanou, A.B. Engin, A.O. Docea, C. Constantin et al.,
Protein bio-corona: critical issue in immune nanotoxicology. Arch. Toxicol. 91(3), 1031–
1048 (2017)
13. P. Rivera-Gil, D. Jimenez de Aberasturi, V. Wulf, B. Pelaz, P. del Pino, Y. Zhao et al., The
challenge to relate the physicochemical properties of colloidal nanoparticles to their
cytotoxicity. Acc. Chem. Res. 46(3), 743–749 (2013)
14. S. Salatin, S. Maleki Dizaj, A. Yari Khosroushahi, Effect of the surface modification, size,
and shape on cellular uptake of nanoparticles. Cell Biol. Int. 39(8), 881–890 (2015)
15. A. Wicki, D. Witzigmann, V. Balasubramanian, J. Huwyler, Nanomedicine in cancer
therapy: challenges, opportunities, and clinical applications. J. Control Release. 200, 138–
157 (2015)
16. P.N. Navya, H.K. Daima, Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives. Nano Convergence
3(1), 1 (2016)
17. X. Sun, W. Cai, X. Chen, Positron emission tomography imaging using radiolabeled
inorganic nanomaterials. Acc. Chem. Res. 48(2), 286–294 (2015)
18. D.C. Julien, S. Behnke, G. Wang, G.K. Murdoch, R.A. Hill, Utilization of monoclonal
antibody-targeted nanomaterials in the treatment of cancer. MAbs 3(5), 467–478 (2011)
19. Y. Bi, F. Hao, G. Yan, L. Teng, R.J. Lee, J. Xie, Actively targeted nanoparticles for drug
delivery to tumor. Curr. Drug Metab. 17(8), 763–782 (2016)
20. A. Salvati, A.S. Pitek, M.P. Monopoli, K. Prapainop, F.B. Bombelli, D.R. Hristov et al.,
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule
corona adsorbs on the surface. Nat. Nanotechnol. 8(2), 137–143 (2013)
21. T. Tashima, Intelligent substance delivery into cells using cell-penetrating peptides. Bioorg.
Med. Chem. Lett. 27(2), 121–130 (2017)
22. M.L. Amin, J.Y. Joo, D.K. Yi, S.S. An, Surface modification and local orientations of
surface molecules in nanotherapeutics. J. Control Release 207, 131–142 (2015)
23. D. Patel, A. Kell, B. Simard, J. Deng, B. Xiang, H.Y. Lin et al., Cu
2+ -labeled, SPION
loaded porous silica nanoparticles for cell labeling and multifunctional imaging probes.
Biomaterials 31(10), 2866–2873 (2010)
24. D. Hong, H. Lee, B.J. Kim, T. Park, J.Y. Choi, M. Park et al., A degradable polydopamine
coating based on disulfide-exchange reaction. Nanoscale 7(47), 20149–20154 (2015)
25. Y. Zhang, C.Y. Ang, M. Li, S.Y. Tan, Q. Qu, Z. Luo et al., Polymer-coated hollow
mesoporous silica nanoparticles for triple-responsive drug delivery. ACS Appl. Mater.
Interfaces 7(32), 18179–18187 (2015)
26. H. Kakwere, M.P. Leal, M.E. Materia, A. Curcio, P. Guardia, D. Niculaes et al.,
Functionalization of strongly interacting magnetic nanocubes with (thermo)responsive
coating and their application in hyperthermia and heat-triggered drug delivery. ACS Appl.
Mater. Interfaces 7(19), 10132–10145 (2015)
27. J. Zhuang, R. Chacko, D.F. Amado Torres, H. Wang, S. Thayumanavan, Dual stimuli—dual
response nanoassemblies prepared from a simple homopolymer. ACS Macro Lett. 3(1), 1–5
(2014)
28. J. Fu, T. Chen, M. Wang, N. Yang, S. Li, Y. Wang et al., Acid and alkaline dual
stimuli-responsive mechanized hollow mesoporous silica nanoparticles as smart nanocontainers for intelligent anticorrosion coatings. ACS Nano 7(12), 11397–11408 (2013)
29. X. Chen, J. Gao, B. Song, M. Smet, X. Zhang, Stimuli-responsive wettability of nonplanar
substrates: pH-controlled floatation and supporting force. Langmuir 26(1), 104–108 (2010)
30. E. Frohlich, Action of nanoparticles on platelet activation and plasmatic coagulation. Curr.
Med. Chem. 23(5), 408–430 (2016)
31. J.P. Almeida, A.L. Chen, A. Foster, R. Drezek, In vivo biodistribution of nanoparticles.
Nanomedicine 6(5), 815–835 (2011) (London, England)
32. J. Nam, N. Won, J. Bang, H. Jin, J. Park, S. Jung et al., Surface engineering of inorganic
nanoparticles for imaging and therapy. Adv. Drug Deliv. Rev. 65(5), 622–648 (2013)
10 Surface Modification of Radionanomedicine
201
Protein bio-corona: critical issue in immune nanotoxicology. Arch. Toxicol. 91(3), 1031–
1048 (2017)
13. P. Rivera-Gil, D. Jimenez de Aberasturi, V. Wulf, B. Pelaz, P. del Pino, Y. Zhao et al., The
challenge to relate the physicochemical properties of colloidal nanoparticles to their
cytotoxicity. Acc. Chem. Res. 46(3), 743–749 (2013)
14. S. Salatin, S. Maleki Dizaj, A. Yari Khosroushahi, Effect of the surface modification, size,
and shape on cellular uptake of nanoparticles. Cell Biol. Int. 39(8), 881–890 (2015)
15. A. Wicki, D. Witzigmann, V. Balasubramanian, J. Huwyler, Nanomedicine in cancer
therapy: challenges, opportunities, and clinical applications. J. Control Release. 200, 138–
157 (2015)
16. P.N. Navya, H.K. Daima, Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives. Nano Convergence
3(1), 1 (2016)
17. X. Sun, W. Cai, X. Chen, Positron emission tomography imaging using radiolabeled
inorganic nanomaterials. Acc. Chem. Res. 48(2), 286–294 (2015)
18. D.C. Julien, S. Behnke, G. Wang, G.K. Murdoch, R.A. Hill, Utilization of monoclonal
antibody-targeted nanomaterials in the treatment of cancer. MAbs 3(5), 467–478 (2011)
19. Y. Bi, F. Hao, G. Yan, L. Teng, R.J. Lee, J. Xie, Actively targeted nanoparticles for drug
delivery to tumor. Curr. Drug Metab. 17(8), 763–782 (2016)
20. A. Salvati, A.S. Pitek, M.P. Monopoli, K. Prapainop, F.B. Bombelli, D.R. Hristov et al.,
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule
corona adsorbs on the surface. Nat. Nanotechnol. 8(2), 137–143 (2013)
21. T. Tashima, Intelligent substance delivery into cells using cell-penetrating peptides. Bioorg.
Med. Chem. Lett. 27(2), 121–130 (2017)
22. M.L. Amin, J.Y. Joo, D.K. Yi, S.S. An, Surface modification and local orientations of
surface molecules in nanotherapeutics. J. Control Release 207, 131–142 (2015)
23. D. Patel, A. Kell, B. Simard, J. Deng, B. Xiang, H.Y. Lin et al., Cu
2+ -labeled, SPION
loaded porous silica nanoparticles for cell labeling and multifunctional imaging probes.
Biomaterials 31(10), 2866–2873 (2010)
24. D. Hong, H. Lee, B.J. Kim, T. Park, J.Y. Choi, M. Park et al., A degradable polydopamine
coating based on disulfide-exchange reaction. Nanoscale 7(47), 20149–20154 (2015)
25. Y. Zhang, C.Y. Ang, M. Li, S.Y. Tan, Q. Qu, Z. Luo et al., Polymer-coated hollow
mesoporous silica nanoparticles for triple-responsive drug delivery. ACS Appl. Mater.
Interfaces 7(32), 18179–18187 (2015)
26. H. Kakwere, M.P. Leal, M.E. Materia, A. Curcio, P. Guardia, D. Niculaes et al.,
Functionalization of strongly interacting magnetic nanocubes with (thermo)responsive
coating and their application in hyperthermia and heat-triggered drug delivery. ACS Appl.
Mater. Interfaces 7(19), 10132–10145 (2015)
27. J. Zhuang, R. Chacko, D.F. Amado Torres, H. Wang, S. Thayumanavan, Dual stimuli—dual
response nanoassemblies prepared from a simple homopolymer. ACS Macro Lett. 3(1), 1–5
(2014)
28. J. Fu, T. Chen, M. Wang, N. Yang, S. Li, Y. Wang et al., Acid and alkaline dual
stimuli-responsive mechanized hollow mesoporous silica nanoparticles as smart nanocontainers for intelligent anticorrosion coatings. ACS Nano 7(12), 11397–11408 (2013)
29. X. Chen, J. Gao, B. Song, M. Smet, X. Zhang, Stimuli-responsive wettability of nonplanar
substrates: pH-controlled floatation and supporting force. Langmuir 26(1), 104–108 (2010)
30. E. Frohlich, Action of nanoparticles on platelet activation and plasmatic coagulation. Curr.
Med. Chem. 23(5), 408–430 (2016)
31. J.P. Almeida, A.L. Chen, A. Foster, R. Drezek, In vivo biodistribution of nanoparticles.
Nanomedicine 6(5), 815–835 (2011) (London, England)
32. J. Nam, N. Won, J. Bang, H. Jin, J. Park, S. Jung et al., Surface engineering of inorganic
nanoparticles for imaging and therapy. Adv. Drug Deliv. Rev. 65(5), 622–648 (2013)
10 Surface Modification of Radionanomedicine
201