kidney were organs of major CNP accumulation. The blood half-life for the
64 Cu-CNPs can be estimated as 27 h by monitoring radioactivity obtained from the
cardiac pool of each experimental tumor-bearing mouse over time.
References
1. G. Romero, S. Moya, Synthesis of organic nanoparticles, in Nanobiotechnology: Inorganic
Nanoparticles vs Organic Nanoparticles, ed. by J. de la Fuente, V. Grazu (Elsevier,
Amsterdam, 2012), pp. 115–141
2. M. Li, K.T. Al-Jamal, K. Kostarelos, J. Reineke, Physiologically based pharma-cokinetic
modeling of nanoparticles. ACS Nano 4, 6303–6317 (2010)
3. A.D. Bangham, M.M. Standish, J.C. Watkins, Diffusion of univalent ions across the lamellae
of swollen phospholipids. J. Mol. Biol. 13, 238–252 (1965)
4. K. Maruyama, Intracellular targeting delivery of liposomal drugs to solid tumors based on
EPR effects. Adv. Drug Deliv. Rev. 63, 161–169 (2011)
5. L. Sercombe, T. Veerati, F. Moheimani, S.Y. Wu, A.K. Sood, S. Hua, Advances and
challenges of liposome assisted drug delivery. Front Pharmacol. 6, 286 (2015)
6. T. van der Geest, P. Laverman, J.M. Metselaar, G. Storm, O.C. Boerman, Radionuclide
imaging of liposomal drug delivery. Expert Opin. Drug Deliv. 13(9), 1231–1242 (2016)
7. D. Liu, A. Mori, L. Huang, Role of liposome size and RES blockade in controlling
biodistribution and tumor uptake of GM1-containing liposomes. Biochim. Biophys. Acta
1104, 95–101 (1992)
8. X. Yan, G.L. Scherphof, J.A. Kamps, Liposome opsonization. J. Liposome Res. 15(1–2),
109–139 (2005)
9. Y. Barenholz, Doxil
®
–the first FDA-approved nano-drug: lessons learned. J. Control Release.
160(2), 117–134 (2012)
10. W.T. Phillips, B.A. Goins, A. Bao, Radioactive liposomes. Wiley Interdiscip. Rev. Nanomed.
Nanobiotechnol. 1(1), 69–83 (2009)
11. G.M. Jensen, T.H. Bunch, Conventional liposome performance and evaluation: lessons from
the development of Vescan. J. Liposome Res. 17, 121–137 (2007)
12. A. Srivatsan, X. Chen, Recent advances in nanoparticle-based nuclear imaging of cancers.
Adv. Cancer Res. 124, 83–129 (2014)
13. A.L. Petersen, A.E. Hansen, A. Gabizon, T.L. Andresen, Liposome imaging agents in
personalized medicine. Adv. Drug Deliv. Rev. 64(13), 1417–1435 (2012)
14. A. Gabizon, R. Chisin, S. Amselem, S. Druckmann, R. Cohen, D. Goren et al.,
Pharmacokinetic and imaging studies in patients receiving a formulation of
liposome-associated adriamycin. Br. J. Cancer 64(6), 1125–1132 (1991)
15. J.R. Morgan, K.E. Williams, R.L. Davies, K. Leach, M. Thomson, L.A. Williams,
Localisation of experimental staphylococcal abscesses by
99m
Tc-technetium-labelled liposomes. J. Med. Microbiol. 14(2), 213–217 (1981)
16. E. Andreozzi, J.W. Seo, K. Ferrara, A. Louie, Novel method to label solid lipid nanoparticles
with
64
Cu for positron emission tomography imaging. Bioconjug. Chem. 22(4), 808–818
(2011)
17. A.L. Petersen, T. Binderup, P. Rasmussen, J.R. Henriksen, D.R. Elema, A. Kjær et al.,
64
Cu
loaded liposomes as positron emission tomography imaging agents. Biomaterials 32(9),
2334–2341 (2011)
18. R.T. Proffitt, L.E. Williams, C.A. Presant, G.W. Tin, J.A. Uliana, R.C. Gamble et al.,
Tumor-imaging potential of liposomes loaded with In-111-NTA: biodistribution in mice.
J. Nucl. Med. 24(1), 45–51 (1983)
120
K. W. Kang and M. G. Song
64 Cu-CNPs can be estimated as 27 h by monitoring radioactivity obtained from the
cardiac pool of each experimental tumor-bearing mouse over time.
References
1. G. Romero, S. Moya, Synthesis of organic nanoparticles, in Nanobiotechnology: Inorganic
Nanoparticles vs Organic Nanoparticles, ed. by J. de la Fuente, V. Grazu (Elsevier,
Amsterdam, 2012), pp. 115–141
2. M. Li, K.T. Al-Jamal, K. Kostarelos, J. Reineke, Physiologically based pharma-cokinetic
modeling of nanoparticles. ACS Nano 4, 6303–6317 (2010)
3. A.D. Bangham, M.M. Standish, J.C. Watkins, Diffusion of univalent ions across the lamellae
of swollen phospholipids. J. Mol. Biol. 13, 238–252 (1965)
4. K. Maruyama, Intracellular targeting delivery of liposomal drugs to solid tumors based on
EPR effects. Adv. Drug Deliv. Rev. 63, 161–169 (2011)
5. L. Sercombe, T. Veerati, F. Moheimani, S.Y. Wu, A.K. Sood, S. Hua, Advances and
challenges of liposome assisted drug delivery. Front Pharmacol. 6, 286 (2015)
6. T. van der Geest, P. Laverman, J.M. Metselaar, G. Storm, O.C. Boerman, Radionuclide
imaging of liposomal drug delivery. Expert Opin. Drug Deliv. 13(9), 1231–1242 (2016)
7. D. Liu, A. Mori, L. Huang, Role of liposome size and RES blockade in controlling
biodistribution and tumor uptake of GM1-containing liposomes. Biochim. Biophys. Acta
1104, 95–101 (1992)
8. X. Yan, G.L. Scherphof, J.A. Kamps, Liposome opsonization. J. Liposome Res. 15(1–2),
109–139 (2005)
9. Y. Barenholz, Doxil
®
–the first FDA-approved nano-drug: lessons learned. J. Control Release.
160(2), 117–134 (2012)
10. W.T. Phillips, B.A. Goins, A. Bao, Radioactive liposomes. Wiley Interdiscip. Rev. Nanomed.
Nanobiotechnol. 1(1), 69–83 (2009)
11. G.M. Jensen, T.H. Bunch, Conventional liposome performance and evaluation: lessons from
the development of Vescan. J. Liposome Res. 17, 121–137 (2007)
12. A. Srivatsan, X. Chen, Recent advances in nanoparticle-based nuclear imaging of cancers.
Adv. Cancer Res. 124, 83–129 (2014)
13. A.L. Petersen, A.E. Hansen, A. Gabizon, T.L. Andresen, Liposome imaging agents in
personalized medicine. Adv. Drug Deliv. Rev. 64(13), 1417–1435 (2012)
14. A. Gabizon, R. Chisin, S. Amselem, S. Druckmann, R. Cohen, D. Goren et al.,
Pharmacokinetic and imaging studies in patients receiving a formulation of
liposome-associated adriamycin. Br. J. Cancer 64(6), 1125–1132 (1991)
15. J.R. Morgan, K.E. Williams, R.L. Davies, K. Leach, M. Thomson, L.A. Williams,
Localisation of experimental staphylococcal abscesses by
99m
Tc-technetium-labelled liposomes. J. Med. Microbiol. 14(2), 213–217 (1981)
16. E. Andreozzi, J.W. Seo, K. Ferrara, A. Louie, Novel method to label solid lipid nanoparticles
with
64
Cu for positron emission tomography imaging. Bioconjug. Chem. 22(4), 808–818
(2011)
17. A.L. Petersen, T. Binderup, P. Rasmussen, J.R. Henriksen, D.R. Elema, A. Kjær et al.,
64
Cu
loaded liposomes as positron emission tomography imaging agents. Biomaterials 32(9),
2334–2341 (2011)
18. R.T. Proffitt, L.E. Williams, C.A. Presant, G.W. Tin, J.A. Uliana, R.C. Gamble et al.,
Tumor-imaging potential of liposomes loaded with In-111-NTA: biodistribution in mice.
J. Nucl. Med. 24(1), 45–51 (1983)
120
K. W. Kang and M. G. Song