Torosantucci A, Chiani P, Bromuro C, De Bernardis F, Palma AS, Liu Y, Mignogna G, Maras B,
Colone M, Stringaro A, Zamboni S, Feizi T, Cassone A (2009) Protection by anti-beta-glucan
antibodies is associated with restricted beta-1,3 glucan binding specificity and inhibition of
fungal growth and adherence. PLoS One 4(4):e5392. https://doi.org/10.1371/journal.pone.
0005392
Tremblay R, Wang D, Jevnikar AM, Ma S (2010) Tobacco, a highly efficient green bioreactor
for production of therapeutic proteins. Biotechnol Adv 28(2):214–221. https://doi.org/10.1016/
j.biotechadv.2009.11.008
Tschofen M, Knopp D, Hood E, Stöger E (2016) Plant molecular farming: much more than
medicines. Annu Rev Anal Chem (Palo Alto, Calif) 9(1):271–294. https://doi.org/10.1146/
annurev-anchem-071015-041706
Tuboly T, Yu W, Bailey A, Degrandis S, Du S, Erickson L, Nagy E (2000) Immunogenicity
of porcine transmissible gastroenteritis virus spike protein expressed in plants. Vaccine
18(19):2023–2028
Ullisch DA, Müller CA, Maibaum S, Kirchhoff J, Schiermeyer A, Schillberg S, Roberts JL,
Treffenfeldt W, Büchs J (2012) Comprehensive characterization of two different Nicotiana
tabacum cell lines leads to doubled GFP and HA protein production by media optimization.
J Biosci Bioeng 113(2):242–248. https://doi.org/10.1016/j.jbiosc.2011.09.022
Vaquero C, Sack M, Schuster F, Finnern R, Drossard J, Schumann D, Reimann A, Fischer R (2002)
A carcinoembryonic antigen-specific diabody produced in tobacco. FASEB J 16(3):408–410.
https://doi.org/10.1096/fj.01-0363fje
Venuti A, Massa S, Mett V, Vedova LD, Paolini F, Franconi R, Yusibov V (2009) An
E7-based therapeutic vaccine protects mice against HPV16 associated cancer. Vaccine
27(25–26):3395–3397. https://doi.org/10.1016/j.vaccine.2009.01.068
von Schomberg R (2013) Prospects for technology assessment in a framework of responsible
research and innovation. In: Dusseldorp M, Beecroft R (eds) Estimate technology consequences, educational potential of transdisciplinary methods. Wiley, London, pp 39–62.
ISBN 978-3-531-17908-7. ISBN 978-3-531-93468-6 (eBook). https://doi.org/10.1007/978-3531-93468-6
Ward BJ, Landry N, Trépanier S, Mercier G, Dargis M, Couture M, D'Aoust MA, Vézina LP (2014)
Human antibody response to N-glycans present on plant-made influenza virus-like particle
(VLP) vaccines. Vaccine 32(46):6098–6106. https://doi.org/10.1016/j.vaccine.2014.08.079
Whaley KJ, Morton J, Hume S, Hiatt E, Bratcher B, Klimyuk V, Hiatt A, Pauly M, Zeitlin L (2014)
Emerging antibody-based products. Curr Top Microbiol Immunol 375:107–126. https://doi.org/
10.1007/82_2012_240
Wilson JA, Hevey M, Bakken R, Guest S, Bray M, Schmaljohn AL, Hart MK (2000) Epitopes
involved in antibody-mediated protection from Ebola virus. Science 287:1664–1666
Wongsamuth R, Doran PM (1997) Production of monoclonal antibodies by tobacco hairy roots.
Biotechnol Bioeng 54(5):401–415. https://doi.org/10.1002/(SICI)1097-0290(19970605)
54:5<401::AID-BIT1>3.0.CO;2-I
Woo JW, Kim J, Kwon SI, Corvalán C, Cho SW, Kim H, Kim SG, Kim ST, Choe S, Kim JS (2015)
DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins.
Nat Biotechnol 33(11):1162–1164. https://doi.org/10.1038/nbt.3389
Woods RR, Geyer BC, Mor TS (2008) Hairy-root organ cultures for the production of human
acetylcholinesterase. BMC Biotechnol 8:95102. https://doi.org/10.1186/1472-6750-8-95
Wu J, Yu L, Li L, Hu J, Zhou J, Zhou X (2007) Oral immunization with transgenic rice
seeds expressing VP2 protein of infectious bursal disease virus induces protective immune
responses in chickens. Plant Biotechnol J 5(5):570–578. https://doi.org/10.1111/j.1467-7652.
2007.00270.x
Xu J, Dolan MC, Medrano G, Cramer CL, Weathers PJ (2012) Green factory: plants as
bioproduction platforms for recombinant proteins. Biotechnol Adv 30(5):1171–1184. https://
doi.org/10.1016/j.biotechadv.2011.08.020
Engineering Plants for the Future: Farming with Value-Added Harvest
107
Colone M, Stringaro A, Zamboni S, Feizi T, Cassone A (2009) Protection by anti-beta-glucan
antibodies is associated with restricted beta-1,3 glucan binding specificity and inhibition of
fungal growth and adherence. PLoS One 4(4):e5392. https://doi.org/10.1371/journal.pone.
0005392
Tremblay R, Wang D, Jevnikar AM, Ma S (2010) Tobacco, a highly efficient green bioreactor
for production of therapeutic proteins. Biotechnol Adv 28(2):214–221. https://doi.org/10.1016/
j.biotechadv.2009.11.008
Tschofen M, Knopp D, Hood E, Stöger E (2016) Plant molecular farming: much more than
medicines. Annu Rev Anal Chem (Palo Alto, Calif) 9(1):271–294. https://doi.org/10.1146/
annurev-anchem-071015-041706
Tuboly T, Yu W, Bailey A, Degrandis S, Du S, Erickson L, Nagy E (2000) Immunogenicity
of porcine transmissible gastroenteritis virus spike protein expressed in plants. Vaccine
18(19):2023–2028
Ullisch DA, Müller CA, Maibaum S, Kirchhoff J, Schiermeyer A, Schillberg S, Roberts JL,
Treffenfeldt W, Büchs J (2012) Comprehensive characterization of two different Nicotiana
tabacum cell lines leads to doubled GFP and HA protein production by media optimization.
J Biosci Bioeng 113(2):242–248. https://doi.org/10.1016/j.jbiosc.2011.09.022
Vaquero C, Sack M, Schuster F, Finnern R, Drossard J, Schumann D, Reimann A, Fischer R (2002)
A carcinoembryonic antigen-specific diabody produced in tobacco. FASEB J 16(3):408–410.
https://doi.org/10.1096/fj.01-0363fje
Venuti A, Massa S, Mett V, Vedova LD, Paolini F, Franconi R, Yusibov V (2009) An
E7-based therapeutic vaccine protects mice against HPV16 associated cancer. Vaccine
27(25–26):3395–3397. https://doi.org/10.1016/j.vaccine.2009.01.068
von Schomberg R (2013) Prospects for technology assessment in a framework of responsible
research and innovation. In: Dusseldorp M, Beecroft R (eds) Estimate technology consequences, educational potential of transdisciplinary methods. Wiley, London, pp 39–62.
ISBN 978-3-531-17908-7. ISBN 978-3-531-93468-6 (eBook). https://doi.org/10.1007/978-3531-93468-6
Ward BJ, Landry N, Trépanier S, Mercier G, Dargis M, Couture M, D'Aoust MA, Vézina LP (2014)
Human antibody response to N-glycans present on plant-made influenza virus-like particle
(VLP) vaccines. Vaccine 32(46):6098–6106. https://doi.org/10.1016/j.vaccine.2014.08.079
Whaley KJ, Morton J, Hume S, Hiatt E, Bratcher B, Klimyuk V, Hiatt A, Pauly M, Zeitlin L (2014)
Emerging antibody-based products. Curr Top Microbiol Immunol 375:107–126. https://doi.org/
10.1007/82_2012_240
Wilson JA, Hevey M, Bakken R, Guest S, Bray M, Schmaljohn AL, Hart MK (2000) Epitopes
involved in antibody-mediated protection from Ebola virus. Science 287:1664–1666
Wongsamuth R, Doran PM (1997) Production of monoclonal antibodies by tobacco hairy roots.
Biotechnol Bioeng 54(5):401–415. https://doi.org/10.1002/(SICI)1097-0290(19970605)
54:5<401::AID-BIT1>3.0.CO;2-I
Woo JW, Kim J, Kwon SI, Corvalán C, Cho SW, Kim H, Kim SG, Kim ST, Choe S, Kim JS (2015)
DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins.
Nat Biotechnol 33(11):1162–1164. https://doi.org/10.1038/nbt.3389
Woods RR, Geyer BC, Mor TS (2008) Hairy-root organ cultures for the production of human
acetylcholinesterase. BMC Biotechnol 8:95102. https://doi.org/10.1186/1472-6750-8-95
Wu J, Yu L, Li L, Hu J, Zhou J, Zhou X (2007) Oral immunization with transgenic rice
seeds expressing VP2 protein of infectious bursal disease virus induces protective immune
responses in chickens. Plant Biotechnol J 5(5):570–578. https://doi.org/10.1111/j.1467-7652.
2007.00270.x
Xu J, Dolan MC, Medrano G, Cramer CL, Weathers PJ (2012) Green factory: plants as
bioproduction platforms for recombinant proteins. Biotechnol Adv 30(5):1171–1184. https://
doi.org/10.1016/j.biotechadv.2011.08.020
Engineering Plants for the Future: Farming with Value-Added Harvest
107