673
penicillin prior to actual exposure. In other words, a category of, perhaps, the phenomenon of magnetic resonance, whereby directed mutation is proceeded by some
form of deep awareness in bacteria that obviate the need for actual mutations.
At the global scale, the universality of structure in prokaryotes—plasma membranes, cytoplasm, DNA, and ribosomes that nurture and create proteins—exerts
life’s most dependable (not predictable) organization. As part of this dynamic, the
biosphere’s antiquity and continuing mastermind of unexpected shifts in ecodynamics have hard-wired resistance, biological innovation, various survival strategies, and what would appear to be an ever-increasing flexibility in the realms of
population ecology and the pure mathematics thus far extrapolated from countless
case studies of biological evolution.
10
Unicellular mutation rates are believed to be
at the level of 0.0003 mutations per genome per every cell generation. This translates into approximately 64 human cellular mutations every generation, “~3× or
~2.7×10
−5
per base per 20-year generation”.
11
Stacking these probabilities within cells containing a nucleus and membraneprotected organelles against the fate of a host within the real world pits the templates for organismic self-awareness and the survival-edged championing of that
cellular self against the mirrors reflecting Hobbes, as well as Alfred Lord Tennyson’s
“red tooth and claw” from his 1850 poem, “In Memoriam A. H. H.” Such components of a particular evolutionary mindset are at once political, sociological, and
forever in retreat from the sobering inroads of scientific method (Fig. 73.2).
12
73.5 Rudiments and Behavior of Ideals
Take a microcosm of this great paradox of ever-conflicted populations, all human
societies in turmoil, and a universal desire to somehow configure ideals as alternatives: 25 Brook Street in London, where Handel lived from 1723 until his death in
1759, there composing many of his greatest works, including the 1741 oratorio,
“Messiah.”
Or to adjoining streets in the Dutch Capital of Peace and Justice, The Hague.
Specifically, to a few streets and house numbers: Dunne Bierkade 16a—the Jan van
Goyenhuis, where van Goyen (discussed in some detail in Chap. 19) was painted by
10 See “Mutations Are Random,” Understanding Evolution,” University of California Museum of
Paleontology (UCMP) and the National Center for Science Education, fueled by the National
Science Foundation and the Howard Hughes Medical Institute, 2004, https://evolution.berkeley.
edu/evolibrary/credits.php, Accessed September 20, 2019.
11 See Schneider S, Excoffier L., July 1999, “Estimation of past demographic parameters from the
distribution of pairwise differences when the mutation rates vary among sites: application to
human mitochondrial DNA”. Genetics. 125 (3): 1079–89. PMC 1460660. PMID 10388826.
12 See “A Short Analysis of Tennyson’s ‘Nature Red in Tooth and Claw’ Poem,” January 1, 2016, Dr.
Oliver Tearle, https://interestingliterature.com/2016/01/01/a-short-analysis-of-tennysons-naturered-in-tooth-and-claw-poem/ Accessed September 20, 2019).
73.5 Rudiments and Behavior of Ideals
penicillin prior to actual exposure. In other words, a category of, perhaps, the phenomenon of magnetic resonance, whereby directed mutation is proceeded by some
form of deep awareness in bacteria that obviate the need for actual mutations.
At the global scale, the universality of structure in prokaryotes—plasma membranes, cytoplasm, DNA, and ribosomes that nurture and create proteins—exerts
life’s most dependable (not predictable) organization. As part of this dynamic, the
biosphere’s antiquity and continuing mastermind of unexpected shifts in ecodynamics have hard-wired resistance, biological innovation, various survival strategies, and what would appear to be an ever-increasing flexibility in the realms of
population ecology and the pure mathematics thus far extrapolated from countless
case studies of biological evolution.
10
Unicellular mutation rates are believed to be
at the level of 0.0003 mutations per genome per every cell generation. This translates into approximately 64 human cellular mutations every generation, “~3× or
~2.7×10
−5
per base per 20-year generation”.
11
Stacking these probabilities within cells containing a nucleus and membraneprotected organelles against the fate of a host within the real world pits the templates for organismic self-awareness and the survival-edged championing of that
cellular self against the mirrors reflecting Hobbes, as well as Alfred Lord Tennyson’s
“red tooth and claw” from his 1850 poem, “In Memoriam A. H. H.” Such components of a particular evolutionary mindset are at once political, sociological, and
forever in retreat from the sobering inroads of scientific method (Fig. 73.2).
12
73.5 Rudiments and Behavior of Ideals
Take a microcosm of this great paradox of ever-conflicted populations, all human
societies in turmoil, and a universal desire to somehow configure ideals as alternatives: 25 Brook Street in London, where Handel lived from 1723 until his death in
1759, there composing many of his greatest works, including the 1741 oratorio,
“Messiah.”
Or to adjoining streets in the Dutch Capital of Peace and Justice, The Hague.
Specifically, to a few streets and house numbers: Dunne Bierkade 16a—the Jan van
Goyenhuis, where van Goyen (discussed in some detail in Chap. 19) was painted by
10 See “Mutations Are Random,” Understanding Evolution,” University of California Museum of
Paleontology (UCMP) and the National Center for Science Education, fueled by the National
Science Foundation and the Howard Hughes Medical Institute, 2004, https://evolution.berkeley.
edu/evolibrary/credits.php, Accessed September 20, 2019.
11 See Schneider S, Excoffier L., July 1999, “Estimation of past demographic parameters from the
distribution of pairwise differences when the mutation rates vary among sites: application to
human mitochondrial DNA”. Genetics. 125 (3): 1079–89. PMC 1460660. PMID 10388826.
12 See “A Short Analysis of Tennyson’s ‘Nature Red in Tooth and Claw’ Poem,” January 1, 2016, Dr.
Oliver Tearle, https://interestingliterature.com/2016/01/01/a-short-analysis-of-tennysons-naturered-in-tooth-and-claw-poem/ Accessed September 20, 2019).
73.5 Rudiments and Behavior of Ideals