33
© Springer Nature Switzerland AG 2021
K. Dhusia et al. (eds.), Fungal Siderophores, Fungal Biology,
https://doi.org/10.1007/978-3-030-53077-8_3
Chapter 3
Association of Fungal Siderophores
in Human Diseases: Roles and Treatments
Saranya Jayapalan, Archana Prabahar, and Shankar Arumugam
Authors Saranya Jayapalan and Archana Prabahar have equally contributed to this chapter.
S. Jayapalan (*)
SS TechLogix, Coimbatore, India
A. Prabahar
Vantex, Coimbatore, India
S. Arumugam
Department of Electronics & Communication Engineering, Sri Ramakrishna Institute of
Technology, Coimbatore, India
Contents
3.1 Introduction
34
3.1.1 Human Fungal Diseases
34
3.1.2 Aspergillosis
34
3.2 Role of Siderophores in Fungal Diseases
36
3.3 Association of Siderophoric System in Aspergillus Species and Infections
37
3.3.1 Aspergillus fumigatus
38
3.3.2 Aspergillus nidulans
38
3.3.3 Siderophore Biosynthetic Pathway in A. fumigatus and A. nidulans
38
3.4 Diagnosis of Aspergillosis
43
3.5 Treatment of Aspergillosis
44
3.6 Applications of Fungal Siderophores in Molecular Imaging
45
3.7 Conclusion
45
References
46
Abbreviations
ABPA Allergic bronchopulmonary aspergillosis
AFS
Allergic fungal sinusitis
IA
Invasive aspergillosis
PET
Positron emission tomography
TAFC Triacetylfusarinine C