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wall (Raymond- Bouchard et  al. 2012). The research in this field have gained
attention five decades ago, and interest in exploring the chemical and biological
perspective of siderophore reached the momentum when it was realized that
most aerobic and facultative anaerobic microorganisms synthesize at least one
siderophore for their sustainability (Neilands 1995; Haas 2003). The coordination property of siderophores is well studied by Abdallah et  al. where it was
proven that these compounds form complexes with only higher oxidation state
of iron (Albrecht-Gary et al. 1994). Apart from forming iron complexes, these
siderophores also play a crucial role in process of quorum sensing. Recently, the
investigation suggests that there exists a well- defined link between process of
quorum sensing and siderophores and iron uptake mechanism (McRose et  al.
2018). Kamino et  al. have demonstrated that microbial population in marine
environment respond to artificial addition of siderophores and homoserine lac?
Fig. 2.1 Pathway depicting the uptake of ferric iron through hydroxamate-based siderophore in
Aspergillus fumigatus
2 Inhibition of Siderophores in Blocking Fungal Infection