67
11. Berry, C. L., Sosa-Melgarejo, J. A., & Greenwald, S. E. (1993). The relationship between
wall tension, lamellar thickness, and intercellular junctions in the fetal and adult aorta: Its
relevance to the pathology of dissecting aneurysm. The Journal of Pathology, 169(1), 15–20.
12. Bhatia, S. N., & Ingber, D. E. (2014). Microfluidic organs-on-chips. Nature Biotechnology,
32(8), 760–772.
13. Bonello-Palot, N., et al. (2014). Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment. Atherosclerosis, 237(1), 45–52.
14. Bonnema, D. D., et al. (2007). Effects of age on plasma matrix metalloproteinases (MMPs)
and tissue inhibitor of metalloproteinases (TIMPs). Journal of Cardiac Failure, 13(7),
530–540.
15. Bostrom, K. I., Rajamannan, N. M., & Towler, D. A. (2011). The regulation of valvular and
vascular sclerosis by osteogenic morphogens. Circulation Research, 109(5), 564–577.
16. Brassard, J. A., et al. (2016). Hutchinson-Gilford progeria syndrome as a model for vascular
aging. Biogerontology, 17(1), 129–145.
17. Briones, A. M., et al. (2005). Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries. Autonomic &
Autacoid Pharmacology, 25(4), 155–162.
18. Brooke, B. S., Bayes-Genis, A., & Li, D. Y. (2003). New insights into elastin and vascular
disease. Trends in Cardiovascular Medicine, 13(5), 176–181.
19. Burton, A. C. (1954). Relation of structure to function of the tissues of the wall of blood vessels. Physiological Reviews, 34(4), 619–642.
20. Burton, D. G., & Krizhanovsky, V. (2014). Physiological and pathological consequences of
cellular senescence. Cellular and Molecular Life Sciences, 71(22), 4373–4386.
21. Byon, C. H., et al. (2011). Runx2-upregulated receptor activator of nuclear factor kappaB
ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation
of macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(6), 1387–1396.
22. Campisi, J. (2013). Aging, cellular senescence, and cancer. Annual Review of Physiology,
75(1), 685–705.
23. Capell, B. C., Collins, F. S., & Nabel, E. G. (2007). Mechanisms of cardiovascular disease in
accelerated aging syndromes. Circulation Research, 101(1), 13–26.
24. Carallo, C., et al. (2016). Carotid endothelial shear stress reduction with aging is associated
with plaque development in twelve years. Atherosclerosis, 251, 63–69.
25. Chau, L., Doran, M., & Cooper-White, J. (2009). A novel multishear microdevice for studying cell mechanics. Lab on a Chip, 9(13), 1897–1902.
26. Chennupati, R., et al. (2013). Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes. British Journal of
Pharmacology, 169(7), 1486–1499.
27. Costantino, S., Paneni, F., & Cosentino, F. (2016). Ageing, metabolism and cardiovascular
disease. The Journal of Physiology, 594(8), 2061–2073.
28. Csoka, A. B., et al. (2004). Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell, 3(4), 235–243.
29. Cuhlmann, S., et al. (2011). Disturbed blood flow induces RelA expression via c-Jun
N-terminal kinase 1 a novel mode of NF-kappa B regulation that promotes arterial inflammation. Circulation Research, 108(8), 950–959.
30. Dahl, K. N., et al. (2006). Distinct structural and mechanical properties of the nuclear lamina
in Hutchinson-Gilford progeria syndrome. Proceedings of the National Academy of Sciences
of the United States of America, 103(27), 10271–10276.
31. Davis, E. C. (1993). Endothelial cell connecting filaments anchor endothelial cells to the subjacent elastic lamina in the developing aortic intima of the mouse. Cell and Tissue Research,
272(2), 211–219.
32. Dimri, G. P., et al. (1995). A biomarker that identifies senescent human cells in culture and in
aging skin in vivo. Proceedings of the National Academy of Sciences, 92(20), 9363–9367.
3 Physiological and Pathological Vascular Aging
11. Berry, C. L., Sosa-Melgarejo, J. A., & Greenwald, S. E. (1993). The relationship between
wall tension, lamellar thickness, and intercellular junctions in the fetal and adult aorta: Its
relevance to the pathology of dissecting aneurysm. The Journal of Pathology, 169(1), 15–20.
12. Bhatia, S. N., & Ingber, D. E. (2014). Microfluidic organs-on-chips. Nature Biotechnology,
32(8), 760–772.
13. Bonello-Palot, N., et al. (2014). Prelamin A accumulation in endothelial cells induces premature senescence and functional impairment. Atherosclerosis, 237(1), 45–52.
14. Bonnema, D. D., et al. (2007). Effects of age on plasma matrix metalloproteinases (MMPs)
and tissue inhibitor of metalloproteinases (TIMPs). Journal of Cardiac Failure, 13(7),
530–540.
15. Bostrom, K. I., Rajamannan, N. M., & Towler, D. A. (2011). The regulation of valvular and
vascular sclerosis by osteogenic morphogens. Circulation Research, 109(5), 564–577.
16. Brassard, J. A., et al. (2016). Hutchinson-Gilford progeria syndrome as a model for vascular
aging. Biogerontology, 17(1), 129–145.
17. Briones, A. M., et al. (2005). Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries. Autonomic &
Autacoid Pharmacology, 25(4), 155–162.
18. Brooke, B. S., Bayes-Genis, A., & Li, D. Y. (2003). New insights into elastin and vascular
disease. Trends in Cardiovascular Medicine, 13(5), 176–181.
19. Burton, A. C. (1954). Relation of structure to function of the tissues of the wall of blood vessels. Physiological Reviews, 34(4), 619–642.
20. Burton, D. G., & Krizhanovsky, V. (2014). Physiological and pathological consequences of
cellular senescence. Cellular and Molecular Life Sciences, 71(22), 4373–4386.
21. Byon, C. H., et al. (2011). Runx2-upregulated receptor activator of nuclear factor kappaB
ligand in calcifying smooth muscle cells promotes migration and osteoclastic differentiation
of macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology, 31(6), 1387–1396.
22. Campisi, J. (2013). Aging, cellular senescence, and cancer. Annual Review of Physiology,
75(1), 685–705.
23. Capell, B. C., Collins, F. S., & Nabel, E. G. (2007). Mechanisms of cardiovascular disease in
accelerated aging syndromes. Circulation Research, 101(1), 13–26.
24. Carallo, C., et al. (2016). Carotid endothelial shear stress reduction with aging is associated
with plaque development in twelve years. Atherosclerosis, 251, 63–69.
25. Chau, L., Doran, M., & Cooper-White, J. (2009). A novel multishear microdevice for studying cell mechanics. Lab on a Chip, 9(13), 1897–1902.
26. Chennupati, R., et al. (2013). Endothelium-dependent hyperpolarization-related relaxations diminish with age in murine saphenous arteries of both sexes. British Journal of
Pharmacology, 169(7), 1486–1499.
27. Costantino, S., Paneni, F., & Cosentino, F. (2016). Ageing, metabolism and cardiovascular
disease. The Journal of Physiology, 594(8), 2061–2073.
28. Csoka, A. B., et al. (2004). Genome-scale expression profiling of Hutchinson-Gilford progeria syndrome reveals widespread transcriptional misregulation leading to mesodermal/mesenchymal defects and accelerated atherosclerosis. Aging Cell, 3(4), 235–243.
29. Cuhlmann, S., et al. (2011). Disturbed blood flow induces RelA expression via c-Jun
N-terminal kinase 1 a novel mode of NF-kappa B regulation that promotes arterial inflammation. Circulation Research, 108(8), 950–959.
30. Dahl, K. N., et al. (2006). Distinct structural and mechanical properties of the nuclear lamina
in Hutchinson-Gilford progeria syndrome. Proceedings of the National Academy of Sciences
of the United States of America, 103(27), 10271–10276.
31. Davis, E. C. (1993). Endothelial cell connecting filaments anchor endothelial cells to the subjacent elastic lamina in the developing aortic intima of the mouse. Cell and Tissue Research,
272(2), 211–219.
32. Dimri, G. P., et al. (1995). A biomarker that identifies senescent human cells in culture and in
aging skin in vivo. Proceedings of the National Academy of Sciences, 92(20), 9363–9367.
3 Physiological and Pathological Vascular Aging