35
81. Rhodes, J. M., & Simons, M. (2007). The extracellular matrix and blood vessel formation:
Not just a scaffold. Journal of Cellular and Molecular Medicine, 11, 176–205.
82. Rupp, P. A., Czirok, A., & Little, C. D. (2003). Novel approaches for the study of vascular assembly and morphogenesis in avian embryos. Trends in Cardiovascular Medicine, 13,
283–288.
83. Sacharidou, A., Koh, W., Stratman, A. N., Mayo, A. M., Fisher, K. E., & Davis, G. E. (2010).
Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through
interdependent Cdc42- and MT1-MMP-mediated events. Blood, 115(25), 5259–5269.
84. Sacharidou, A., Stratman, A. N., & Davis, G. E. (2012). Molecular mechanisms controlling
vascular lumen formation in three-dimensional extracellular matrices. Cells, Tissues, Organs,
195, 122–143. https://doi.org/10.1159/000331410
85. San Antonio, J. D., Zoeller, J. J., Habursky, K., Turner, K., Pimtong, W., Burrows, M., et al.
(2009). A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. The American Journal of Pathology, 175, 1338–1347.
86. Saunders, W. B., Bayless, K. J., & Davis, G. E. (2005). MMP-1 activation by serine proteases
and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. Journal of Cell Science, 118, 2325–2340.
87. Saunders, W. B., Bohnsack, B. L., Faske, J. B., Anthis, N. J., Bayless, K. J., Hirschi, K. K.,
et al. (2006). Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. The Journal of Cell Biology, 175, 179–191.
88. Senger, D. R., Claffey, K. P., Benes, J. E., Perruzzi, C. A., Sergiou, A. P., & Detmar, M.
(1997). Angiogenesis promoted by vascular endothelial growth factor: Regulation through
alpha1beta1 and alpha2beta1 integrins. Proceedings of the National Academy of Sciences of
the United States of America, 94, 13612–13617.
89. Senger, D. R., & Davis, G. E. (2011). Angiogenesis. Cold Spring Harbor Perspectives in
Biology, 3, a005090. https://doi.org/10.1101/cshperspect.a005090
90. Seo, D. W., Li, H., Guedez, L., Wingfield, P. T., Diaz, T., Salloum, R., et al. (2003). TIMP-2
mediated inhibition of angiogenesis: An MMP-independent mechanism. Cell, 114, 171–180.
91. Smith, A. O., Bowers, S. L., Stratman, A. N., & Davis, G. E. (2013). Hematopoietic stem cell
cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube coassembly in 3D fibrin matrices under serum-free defined conditions. PLoS One, 8, e85147.
https://doi.org/10.1371/journal.pone.0085147
92. Stratman, A. N., & Davis, G. E. (2012). Endothelial cell-pericyte interactions stimulate
basement membrane matrix assembly: Influence on vascular tube remodeling, maturation, and stabilization. Microscopy and Microanalysis, 18, 68–80. https://doi.org/10.1017/
S1431927611012402
93. Stratman, A. N., Davis, M. J., & Davis, G. E. (2011). VEGF and FGF prime vascular tube
morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood, 117,
3709–3719. https://doi.org/10.1182/blood-2010-11-316752
94. Stratman, A. N., Malotte, K. M., Mahan, R. D., Davis, M. J., & Davis, G. E. (2009). Pericyte
recruitment during vasculogenic tube assembly stimulates endothelial basement membrane
matrix formation. Blood, 114, 5091–5101.
95. Stratman, A. N., Saunders, W. B., Sacharidou, A., Koh, W., Fisher, K. E., Zawieja, D. C., et al.
(2009). Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMPdependent proteolysis in 3-dimensional collagen matrices. Blood, 114, 237–247.
96. Stratman, A. N., Schwindt, A. E., Malotte, K. M., & Davis, G. E. (2010). Endothelialderived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood, 116, 4720–4730. https://doi.org/10.1182/
blood-2010-05-286872
97. Stupack, D. G., & Cheresh, D. A. (2004). Integrins and angiogenesis. Current Topics in
Developmental Biology, 64, 207–238.
98. Tian, Y., Lei, L., Cammarano, M., Nekrasova, T., & Minden, A. (2009). Essential role for the
Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mechanisms
of Development, 126, 710–720.
1 Molecular Control of Capillary Tube Morphogenesis and Maturation Through…
81. Rhodes, J. M., & Simons, M. (2007). The extracellular matrix and blood vessel formation:
Not just a scaffold. Journal of Cellular and Molecular Medicine, 11, 176–205.
82. Rupp, P. A., Czirok, A., & Little, C. D. (2003). Novel approaches for the study of vascular assembly and morphogenesis in avian embryos. Trends in Cardiovascular Medicine, 13,
283–288.
83. Sacharidou, A., Koh, W., Stratman, A. N., Mayo, A. M., Fisher, K. E., & Davis, G. E. (2010).
Endothelial lumen signaling complexes control 3D matrix-specific tubulogenesis through
interdependent Cdc42- and MT1-MMP-mediated events. Blood, 115(25), 5259–5269.
84. Sacharidou, A., Stratman, A. N., & Davis, G. E. (2012). Molecular mechanisms controlling
vascular lumen formation in three-dimensional extracellular matrices. Cells, Tissues, Organs,
195, 122–143. https://doi.org/10.1159/000331410
85. San Antonio, J. D., Zoeller, J. J., Habursky, K., Turner, K., Pimtong, W., Burrows, M., et al.
(2009). A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. The American Journal of Pathology, 175, 1338–1347.
86. Saunders, W. B., Bayless, K. J., & Davis, G. E. (2005). MMP-1 activation by serine proteases
and MMP-10 induces human capillary tubular network collapse and regression in 3D collagen matrices. Journal of Cell Science, 118, 2325–2340.
87. Saunders, W. B., Bohnsack, B. L., Faske, J. B., Anthis, N. J., Bayless, K. J., Hirschi, K. K.,
et al. (2006). Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. The Journal of Cell Biology, 175, 179–191.
88. Senger, D. R., Claffey, K. P., Benes, J. E., Perruzzi, C. A., Sergiou, A. P., & Detmar, M.
(1997). Angiogenesis promoted by vascular endothelial growth factor: Regulation through
alpha1beta1 and alpha2beta1 integrins. Proceedings of the National Academy of Sciences of
the United States of America, 94, 13612–13617.
89. Senger, D. R., & Davis, G. E. (2011). Angiogenesis. Cold Spring Harbor Perspectives in
Biology, 3, a005090. https://doi.org/10.1101/cshperspect.a005090
90. Seo, D. W., Li, H., Guedez, L., Wingfield, P. T., Diaz, T., Salloum, R., et al. (2003). TIMP-2
mediated inhibition of angiogenesis: An MMP-independent mechanism. Cell, 114, 171–180.
91. Smith, A. O., Bowers, S. L., Stratman, A. N., & Davis, G. E. (2013). Hematopoietic stem cell
cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube coassembly in 3D fibrin matrices under serum-free defined conditions. PLoS One, 8, e85147.
https://doi.org/10.1371/journal.pone.0085147
92. Stratman, A. N., & Davis, G. E. (2012). Endothelial cell-pericyte interactions stimulate
basement membrane matrix assembly: Influence on vascular tube remodeling, maturation, and stabilization. Microscopy and Microanalysis, 18, 68–80. https://doi.org/10.1017/
S1431927611012402
93. Stratman, A. N., Davis, M. J., & Davis, G. E. (2011). VEGF and FGF prime vascular tube
morphogenesis and sprouting directed by hematopoietic stem cell cytokines. Blood, 117,
3709–3719. https://doi.org/10.1182/blood-2010-11-316752
94. Stratman, A. N., Malotte, K. M., Mahan, R. D., Davis, M. J., & Davis, G. E. (2009). Pericyte
recruitment during vasculogenic tube assembly stimulates endothelial basement membrane
matrix formation. Blood, 114, 5091–5101.
95. Stratman, A. N., Saunders, W. B., Sacharidou, A., Koh, W., Fisher, K. E., Zawieja, D. C., et al.
(2009). Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMPdependent proteolysis in 3-dimensional collagen matrices. Blood, 114, 237–247.
96. Stratman, A. N., Schwindt, A. E., Malotte, K. M., & Davis, G. E. (2010). Endothelialderived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood, 116, 4720–4730. https://doi.org/10.1182/
blood-2010-05-286872
97. Stupack, D. G., & Cheresh, D. A. (2004). Integrins and angiogenesis. Current Topics in
Developmental Biology, 64, 207–238.
98. Tian, Y., Lei, L., Cammarano, M., Nekrasova, T., & Minden, A. (2009). Essential role for the
Pak4 protein kinase in extraembryonic tissue development and vessel formation. Mechanisms
of Development, 126, 710–720.
1 Molecular Control of Capillary Tube Morphogenesis and Maturation Through…