113
stromal cells expressing hypoxia inducible factor 1alpha. Journal of Cellular Physiology,
221(1), 54–66.
117. Jiang, M., Wang, B., Wang, C., He, B., Fan, H., Guo, T. B., et al. (2008). Angiogenesis
by transplantation of HIF-1 alpha modified EPCs into ischemic limbs. Journal of Cellular
Biochemistry, 103(1), 321–334.
118. Jones 3rd, C. I., Han, Z., Presley, T., Varadharaj, S., Zweier, J. L., Ilangovan, G., et al. (2008).
Endothelial cell respiration is affected by the oxygen tension during shear exposure: Role
of mitochondrial peroxynitrite. American Journal of Physiology. Cell Physiology, 295(1),
C180–C191.
119. Kang, X. L., Wei, X. X., Wang, X. H., Jiang, L., Niu, C., Zhang, J. Y., et al. (2016). Nox2
contributes to the arterial endothelial specification of mouse induced pluripotent stem cells
by upregulating notch signaling. Scientific Reports, 6, 13.
120. Kellner, K., Liebsch, G., Klimant, I., Wolfbeis, O. S., Blunk, T., Schulz, M. B., et al.
(2002). Determination of oxygen gradients in engineered tissue using a fluorescent sensor.
Biotechnology and Bioengineering, 80(1), 73–83.
121. Khetan, S., Chung, C., & Burdick, J. A. (2009). Tuning hydrogel properties for applications
in tissue engineering. Conference Proceedings: Annual International Conference of the IEEE
Engineering in Medicine and Biology Society, 1, 2094–2096.
122. Kilarski, W. W., Samolov, B., Petersson, L., Kvanta, A., & Gerwins, P. (2009). Biomechanical
regulation of blood vessel growth during tissue vascularization. Nature Medicine, 15(6),
657–664.
123. Kloxin, A. M., Kasko, A. M., Salinas, C. N., & Anseth, K. S. (2009). Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science, 324(5923), 59–63.
124. Klumb, L. A., & Horbett, T. A. (1992). Design of insulin delivery devices based on glucose
sensitive membranes. Journal of Controlled Release, 18(1), 59–80.
125. Koay, E. J., & Athanasiou, K. A. (2008). Hypoxic chondrogenic differentiation of human
embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality.
Osteoarthritis and Cartilage, 16(12), 1450–1456.
126. Koh, M. Y., & Powis, G. (2012). Passing the baton: The HIF switch. Trends in Biochemical
Sciences, 37(9), 364–372.
127. Koh, W., Stratman, A. N., Sacharidou, A., & Davis, G. E. (2008). In vitro three dimensional
collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis. Methods in Enzymology, 443, 83–101.
128. Koike, N., et al. (2004). Tissue engineering: Creation of long-lasting blood vessels. Nature,
428, 138.
129. Korin, N., Bransky, A., Dinnar, U., & Levenberg, S. (2009). Periodic “flow-stop” perfusion
microchannel bioreactors for mammalian and human embryonic stem cell long-term culture.
Biomedical Microdevices, 11(1), 87–94.
130. Kreger, S. T., & Voytik-Harbin, S. L. (2009). Hyaluronan concentration within a 3D collagen
matrix modulates matrix viscoelasticity, but not fibroblast response. Matrix Biology, 28(6),
336–346.
131. Kumar, R., Stepanek, F., & Mantalaris, A. (2003). A conceptual model for oxygen transport in the human marrow. Modelling and Control in Biomedical Systems 2003 (Including
Biological Systems). pp. 365–370.
132. Kumar, R., Stepanek, F., & Mantalaris, A. (2004). An oxygen transport model for human
bone marrow microcirculation. Food and Bioproducts Processing, 82(C2), 105–116.
133. Kumar, R., Panoskaltsis, N., Stepanek, F., & Mantalaris, A. (2008). Coupled oxygen-carbon
dioxide transport model for the human bone marrow. Food and Bioproducts Processing,
86(C3), 211–219.
134. Kusuma, S., Zhao, S., & Gerecht, S. (2012). The extracellular matrix is a novel attribute
of endothelial progenitors and of hypoxic mature endothelial cells. FASEB Journal, 26(12),
4925–4936.
135. Kusuma, S., Peijnenburg, E., Patel, P., & Gerecht, S. (2014). Low oxygen tension enhances
endothelial fate of human pluripotent stem cells. Arteriosclerosis, Thrombosis, and Vascular
Biology, 34(4), 913–920.
4 Hypoxia and Matrix Manipulation for Vascular Engineering
stromal cells expressing hypoxia inducible factor 1alpha. Journal of Cellular Physiology,
221(1), 54–66.
117. Jiang, M., Wang, B., Wang, C., He, B., Fan, H., Guo, T. B., et al. (2008). Angiogenesis
by transplantation of HIF-1 alpha modified EPCs into ischemic limbs. Journal of Cellular
Biochemistry, 103(1), 321–334.
118. Jones 3rd, C. I., Han, Z., Presley, T., Varadharaj, S., Zweier, J. L., Ilangovan, G., et al. (2008).
Endothelial cell respiration is affected by the oxygen tension during shear exposure: Role
of mitochondrial peroxynitrite. American Journal of Physiology. Cell Physiology, 295(1),
C180–C191.
119. Kang, X. L., Wei, X. X., Wang, X. H., Jiang, L., Niu, C., Zhang, J. Y., et al. (2016). Nox2
contributes to the arterial endothelial specification of mouse induced pluripotent stem cells
by upregulating notch signaling. Scientific Reports, 6, 13.
120. Kellner, K., Liebsch, G., Klimant, I., Wolfbeis, O. S., Blunk, T., Schulz, M. B., et al.
(2002). Determination of oxygen gradients in engineered tissue using a fluorescent sensor.
Biotechnology and Bioengineering, 80(1), 73–83.
121. Khetan, S., Chung, C., & Burdick, J. A. (2009). Tuning hydrogel properties for applications
in tissue engineering. Conference Proceedings: Annual International Conference of the IEEE
Engineering in Medicine and Biology Society, 1, 2094–2096.
122. Kilarski, W. W., Samolov, B., Petersson, L., Kvanta, A., & Gerwins, P. (2009). Biomechanical
regulation of blood vessel growth during tissue vascularization. Nature Medicine, 15(6),
657–664.
123. Kloxin, A. M., Kasko, A. M., Salinas, C. N., & Anseth, K. S. (2009). Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science, 324(5923), 59–63.
124. Klumb, L. A., & Horbett, T. A. (1992). Design of insulin delivery devices based on glucose
sensitive membranes. Journal of Controlled Release, 18(1), 59–80.
125. Koay, E. J., & Athanasiou, K. A. (2008). Hypoxic chondrogenic differentiation of human
embryonic stem cells enhances cartilage protein synthesis and biomechanical functionality.
Osteoarthritis and Cartilage, 16(12), 1450–1456.
126. Koh, M. Y., & Powis, G. (2012). Passing the baton: The HIF switch. Trends in Biochemical
Sciences, 37(9), 364–372.
127. Koh, W., Stratman, A. N., Sacharidou, A., & Davis, G. E. (2008). In vitro three dimensional
collagen matrix models of endothelial lumen formation during vasculogenesis and angiogenesis. Methods in Enzymology, 443, 83–101.
128. Koike, N., et al. (2004). Tissue engineering: Creation of long-lasting blood vessels. Nature,
428, 138.
129. Korin, N., Bransky, A., Dinnar, U., & Levenberg, S. (2009). Periodic “flow-stop” perfusion
microchannel bioreactors for mammalian and human embryonic stem cell long-term culture.
Biomedical Microdevices, 11(1), 87–94.
130. Kreger, S. T., & Voytik-Harbin, S. L. (2009). Hyaluronan concentration within a 3D collagen
matrix modulates matrix viscoelasticity, but not fibroblast response. Matrix Biology, 28(6),
336–346.
131. Kumar, R., Stepanek, F., & Mantalaris, A. (2003). A conceptual model for oxygen transport in the human marrow. Modelling and Control in Biomedical Systems 2003 (Including
Biological Systems). pp. 365–370.
132. Kumar, R., Stepanek, F., & Mantalaris, A. (2004). An oxygen transport model for human
bone marrow microcirculation. Food and Bioproducts Processing, 82(C2), 105–116.
133. Kumar, R., Panoskaltsis, N., Stepanek, F., & Mantalaris, A. (2008). Coupled oxygen-carbon
dioxide transport model for the human bone marrow. Food and Bioproducts Processing,
86(C3), 211–219.
134. Kusuma, S., Zhao, S., & Gerecht, S. (2012). The extracellular matrix is a novel attribute
of endothelial progenitors and of hypoxic mature endothelial cells. FASEB Journal, 26(12),
4925–4936.
135. Kusuma, S., Peijnenburg, E., Patel, P., & Gerecht, S. (2014). Low oxygen tension enhances
endothelial fate of human pluripotent stem cells. Arteriosclerosis, Thrombosis, and Vascular
Biology, 34(4), 913–920.
4 Hypoxia and Matrix Manipulation for Vascular Engineering