218
L. S. Emery and J. M. Akey
Table 1
(continued)
Study
Data
Statistic
Population(s)
# Candidates found Candidate regions of note
Pickrell et al. (2009)
650 K SNPs
LD (iHS)
Population
differentiation (XP-EHH,
F
ST )
53 HGDP populations
60 regions (only
looked at 10 most
extreme scores in
each world
region)
SLC24A5
EDAR
Sabeti et al. (2007)
3.1 M SNPs
LD (rEHH, iHS,
XP-EHH)
3 HapMap II
22 regions
EDAR
SLC24A5
HERC1
PCDH15
Tang et al. (2007)
1.5 M Perlegen SNPs
3.6 M HapMap SNPs
LD (ln[Rsb])
3 HapMap II, Perlegen
298 regions
SLC24A5
ALMS1
EDAR
LCT
TRPV6
Tennessen and Akey
(2011)
100 K SNPs
Parallel divergence (F
ST
in independent pop
comparisons)
19 of HGDP pops
~5000 unique
SNPs
~1300 unique
genes
ALMS1
PCDH15
HERC2
APOB
Tennessen et al.
(2010)
25,769 kb exome
sequence
(~56,000 SNPs)
4 African, 6 European
281 previous
candidate regions
TRPV6
SLC24A5
Voight et al. (2006)
1 M SNPs
LD (iHS)
3 HapMap I
431 regions
SLC24A5
LCT