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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930524/
42. AlFakeeh A, Brezden-Masley C. Overcoming endocrine resistance in hormone receptor-positive
breast cancer. Curr Oncol Tor Ont. 2018;25(Suppl 1):S18–27.
43. Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, et al. Detection of circulating
tumor DNA in early- and late-stage human malignancies. Sci Transl Med. 2014;6(224):224ra24.
44. Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, et al. Perspective on
oncogenic processes at the end of the beginning of cancer genomics. Cell. 2018;173(2):305–320.
e10.
45. International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C,
et al. International network of cancer genome projects. Nature. 2010;464(7291):993–8.
46. Zhang J, Bajari R, Andric D, Gerthoffert F, Lepsa A, Nahal-Bose H, et al. The International
Cancer Genome Consortium Data Portal. Nat Biotechnol. 2019;37(4):367–9.
47. Campbell PJ, Getz G, Stuart JM, Korbel JO, Stein LD. Pan-cancer analysis of whole genomes.
bioRxiv. 2017:162784.
48. Tate JG, Bamford S, Jubb HC, Sondka Z, Beare DM, Bindal N, et al. COSMIC: the Catalogue Of
Somatic Mutations In Cancer. Nucleic Acids Res. 2019;47(D1):D941–7.
49. Landrum MJ, Lee JM, Riley GR, Jang W, Rubinstein WS, Church DM, et al. ClinVar: public
archive of relationships among sequence variation and human phenotype. Nucleic Acids Res.
2014;42(Database issue):D980–5.
50. Turnbull C, Scott RH, Thomas E, Jones L, Murugaesu N, Pretty FB, et al. The 100 000 genomes
project: bringing whole genome sequencing to the NHS. BMJ. 2018;24(361):k1687.
51. biobank [Internet]. UK Biobank leads the way in genetics research to tackle chronic diseases.
2019. Available from: https://www.ukbiobank.ac.uk/2019/09/uk-biobank-leads-the-way-ingenetics-research-to-tackle-chronic-diseases/.
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Precision Medicine Initiative. 2015. Available from: https://obamawhitehouse.archives.gov/thepress-office/2015/01/30/fact-sheet-president-obama-s-precision-medicine-initiative
53. Shendure J, Findlay GM, Snyder MW. Genomic medicine-progress, pitfalls, and promise. Cell.
2019;177(1):45–57.
54. Norton ME, Wapner RJ. Cell-free DNA analysis for noninvasive examination of trisomy. N Engl
J Med. 2015 24;373(26):2582.
55. Johnson SB, Slade I, Giubilini A, Graham M. Rethinking the ethical principles of genomic
medicine services. Eur J Hum Genet EJHG. 2020;28(2):147–54.
38
C. Molina-Aguilar et al.