Sauer M, Porro D, Mattanovich D, Branduardi P (2008) Microbial production of organic acids:
expanding the markets. Trends Biotechnol 26(2):100–108
Savir Y, Noor E, Milo R, Tlusty T (2010) Cross-species analysis traces adaptation of Rubisco
toward optimality in a low-dimensional landscape. Proc Natl Acad Sci USA 107:3475–3480
Savka MA, Farrand SK (1997) Modification of rhizobacterial populations by engineering bacterium
utilization of a novel plant-produced resource. Nat Biotechnol 15:363–368
Savka MA, Dessaux Y, Oger P, Rossbach S (2002) Engineering bacterial competitiveness and
persistence in the phytosphere. Mol Plant-Microbe Interact 15:866–874
Sawai S, Ohyama K, Yasumoto S, Seki H, Sakuma T, Yamamoto T, Takebayashi Y, Kojima M,
Sakakibara H, Aoki T, Muranaka T, Saito K, Umemotog N (2014) Sterol side chain reductase
2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal
glycoalkaloids in potato. Plant Cell 26:3763–3774
Sawant S, Singh PK, Madanala R, Tuli R (2001) Designing of an artificial expression cassette for
the high-level expression of transgenes in plants. Theor Appl Genet 102:635–644
Schaefer DG, Zryd J-P (1997) Efficient gene targeting in the moss Physcomitrella patens. Plant J
11:1195–1206
Schuler ML, Mantegazza O, Weber AP (2016) Engineering C4 photosynthesis into C3 chassis in
the synthetic biology age. Plant J 87:51–65
Schwander T, Von Borzyskowski LS, Burgener S, Cortina NS, Erb TJ (2016) A synthetic pathway
for the fixation of carbon dioxide in vitro. Science 354(6314):900–904
Scott SA, Davey MP, Dennis JS, Horst I, Howe CJ, Lea-Smith DJ, Smith AG (2010) Biodiesel from
algae: challenges and prospects. Curr Opin Biotechnol 21:277–286
Serrano L (2007) Synthetic biology: promises and challenges. Mol Syst Biol 3(158):158
Setten L, Soto G, Mozzicafreddo M, Fox AR, Lisi C, Cuccioloni M, Angeletti M, Pagano E, DíazPaleo A, Ayub ND (2013) Engineering Pseudomonas protegens Pf-5 for nitrogen fixation and
its application to improve plant growth under nitrogen-deficient conditions. PLoS One 8:e63666
Shan Q, Wang Y, Li J, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi JJ, Qiu J-L, Gao C (2013)
Targeted genome modification of crop plants using a CRISPR-Cas system. Nat Biotechnol
31:686–688
Shen B, Sun X, Zuo X, Shilling T, Apgar J, Ross M, Bougri O, Samoylov V, Parker M, Hancock E,
Lucero H, Gray B, Ekborg NA, Zhang D, Johnson JCS, Lazar G, Raab RM (2012) Engineering
a thermoregulated intein-modified xylanase into maize for consolidated lignocellulosic biomass
processing. Nat Biotechnol 30:1131–1136
Shen BR, Wang LM, Lin XL, Yao Z, Xu HW, Zhu CH, Teng HY, Cui LL, Liu EE, Zhang JJ, He
Z-H, Peng X-X (2019) Engineering a new chloroplastic photorespiratory bypass to increase
photosynthetic efficiency and productivity in rice. Mol Plant 12:199–214
Shetty RS, Deo SK, Shah P, Sun Y, Rosen BP, Daunert S (2003) Luminescence-based whole-cellsensing systems for cadmium and lead using genetically engineered bacteria. Anal Bioanal
Chem 376:11–17
Shi J, Gao H, Wang H et al (2017) ARGOS8 variants generated by CRISPR-Cas9 improve maize
grain yield under field drought stress conditions. Plant Biotechnol J 15(2):207–216
Shih PM, Liang Y, Loqué D (2016) Biotechnology and synthetic biology approaches for metabolic
engineering of bioenergy crops. Plant J 87(1):103–117
Shimatani Z, Kashojiya S, Takayama M et al (2017) Targeted base editing in rice and tomato using
a CRISPR-Cas9 cytidine deaminase fusion. Nat Biotechnol 35:441–443
Shokouhifar F, Zamani MR, Motallebi M, Mousavi A, Malboobi MA (2011) Construction and
functional analysis of pathogen-inducible synthetic promoters in Brassica napus. Biol Plant 55
(4):689
Singh S, Dutt D, Tyagi CH, Upadhyaya JS (2011) Bio-conventional bleaching of wheat straw sodaAQ pulp with crude xylanases from SH-1 NTCC-1163 and SH-2 NTCC-1164 strains of
Coprinellus disseminatus to mitigate AOX generation. New Biotechnol 28(1):47–57
Singh RL, Singh PK, Singh RP (2015) Enzymatic decolorization and degradation of azo dyes – a
review. Int Biodeterior Biodegradation 104:21–31
15 Plant Synthetic Biology: A Paradigm Shift Targeting Stress Mitigation,. . .
485
expanding the markets. Trends Biotechnol 26(2):100–108
Savir Y, Noor E, Milo R, Tlusty T (2010) Cross-species analysis traces adaptation of Rubisco
toward optimality in a low-dimensional landscape. Proc Natl Acad Sci USA 107:3475–3480
Savka MA, Farrand SK (1997) Modification of rhizobacterial populations by engineering bacterium
utilization of a novel plant-produced resource. Nat Biotechnol 15:363–368
Savka MA, Dessaux Y, Oger P, Rossbach S (2002) Engineering bacterial competitiveness and
persistence in the phytosphere. Mol Plant-Microbe Interact 15:866–874
Sawai S, Ohyama K, Yasumoto S, Seki H, Sakuma T, Yamamoto T, Takebayashi Y, Kojima M,
Sakakibara H, Aoki T, Muranaka T, Saito K, Umemotog N (2014) Sterol side chain reductase
2 is a key enzyme in the biosynthesis of cholesterol, the common precursor of toxic steroidal
glycoalkaloids in potato. Plant Cell 26:3763–3774
Sawant S, Singh PK, Madanala R, Tuli R (2001) Designing of an artificial expression cassette for
the high-level expression of transgenes in plants. Theor Appl Genet 102:635–644
Schaefer DG, Zryd J-P (1997) Efficient gene targeting in the moss Physcomitrella patens. Plant J
11:1195–1206
Schuler ML, Mantegazza O, Weber AP (2016) Engineering C4 photosynthesis into C3 chassis in
the synthetic biology age. Plant J 87:51–65
Schwander T, Von Borzyskowski LS, Burgener S, Cortina NS, Erb TJ (2016) A synthetic pathway
for the fixation of carbon dioxide in vitro. Science 354(6314):900–904
Scott SA, Davey MP, Dennis JS, Horst I, Howe CJ, Lea-Smith DJ, Smith AG (2010) Biodiesel from
algae: challenges and prospects. Curr Opin Biotechnol 21:277–286
Serrano L (2007) Synthetic biology: promises and challenges. Mol Syst Biol 3(158):158
Setten L, Soto G, Mozzicafreddo M, Fox AR, Lisi C, Cuccioloni M, Angeletti M, Pagano E, DíazPaleo A, Ayub ND (2013) Engineering Pseudomonas protegens Pf-5 for nitrogen fixation and
its application to improve plant growth under nitrogen-deficient conditions. PLoS One 8:e63666
Shan Q, Wang Y, Li J, Zhang Y, Chen K, Liang Z, Zhang K, Liu J, Xi JJ, Qiu J-L, Gao C (2013)
Targeted genome modification of crop plants using a CRISPR-Cas system. Nat Biotechnol
31:686–688
Shen B, Sun X, Zuo X, Shilling T, Apgar J, Ross M, Bougri O, Samoylov V, Parker M, Hancock E,
Lucero H, Gray B, Ekborg NA, Zhang D, Johnson JCS, Lazar G, Raab RM (2012) Engineering
a thermoregulated intein-modified xylanase into maize for consolidated lignocellulosic biomass
processing. Nat Biotechnol 30:1131–1136
Shen BR, Wang LM, Lin XL, Yao Z, Xu HW, Zhu CH, Teng HY, Cui LL, Liu EE, Zhang JJ, He
Z-H, Peng X-X (2019) Engineering a new chloroplastic photorespiratory bypass to increase
photosynthetic efficiency and productivity in rice. Mol Plant 12:199–214
Shetty RS, Deo SK, Shah P, Sun Y, Rosen BP, Daunert S (2003) Luminescence-based whole-cellsensing systems for cadmium and lead using genetically engineered bacteria. Anal Bioanal
Chem 376:11–17
Shi J, Gao H, Wang H et al (2017) ARGOS8 variants generated by CRISPR-Cas9 improve maize
grain yield under field drought stress conditions. Plant Biotechnol J 15(2):207–216
Shih PM, Liang Y, Loqué D (2016) Biotechnology and synthetic biology approaches for metabolic
engineering of bioenergy crops. Plant J 87(1):103–117
Shimatani Z, Kashojiya S, Takayama M et al (2017) Targeted base editing in rice and tomato using
a CRISPR-Cas9 cytidine deaminase fusion. Nat Biotechnol 35:441–443
Shokouhifar F, Zamani MR, Motallebi M, Mousavi A, Malboobi MA (2011) Construction and
functional analysis of pathogen-inducible synthetic promoters in Brassica napus. Biol Plant 55
(4):689
Singh S, Dutt D, Tyagi CH, Upadhyaya JS (2011) Bio-conventional bleaching of wheat straw sodaAQ pulp with crude xylanases from SH-1 NTCC-1163 and SH-2 NTCC-1164 strains of
Coprinellus disseminatus to mitigate AOX generation. New Biotechnol 28(1):47–57
Singh RL, Singh PK, Singh RP (2015) Enzymatic decolorization and degradation of azo dyes – a
review. Int Biodeterior Biodegradation 104:21–31
15 Plant Synthetic Biology: A Paradigm Shift Targeting Stress Mitigation,. . .
485