E5845–E5853. https://doi.org/10.1073/
pnas.1701703114
117. Gloerich M, Bianchini JM, Siemers KA,
Cohen DJ, Nelson WJ (2017) Cell division
orientation is coupled to cell–cell adhesion by
the E-cadherin/LGN complex. Nat Commun 8:1–11
118. del Rio A, Perez-Jimenez R, Liu R, RocaCusachs P, Fernandez JM, Sheetz MP
(2009) Stretching single talin rod molecules
activates
vinculin
binding.
Science
323:638–641
119. Mitrossilis D, Fouchard J, Pereira D, Postic F,
Richert A, Saint-Jean M, Asnacios A (2010)
Real-time single-cell response to stiffness.
PNAS 107:16518–16523
120. Choquet D, Felsenfeld DP, Sheetz MP
(1997) Extracellular matrix rigidity causes
strengthening of integrin–cytoskeleton linkages. Cell 88:39–48
121. Stehbens SJ, Paszek M, Pemble H,
Ettinger A, Gierke S, Wittmann T (2014)
CLASPs
link
focal-adhesion-associated
microtubule capture to localized exocytosis
and adhesion site turnover. Nat Cell Biol
16:561–573
122. Sackmann E, Smith A-S (2014) Physics of cell
adhesion: some lessons from cell-mimetic systems. Soft Matter 10:1644–1659
123. Riveline D, Zamir E, Balaban NQ, Schwarz
US, Ishizaki T, Narumiya S, Kam Z, Geiger B,
Bershadsky AD (2001) Focal contacts as
mechanosensors externally applied local
mechanical force induces growth of focal contacts by an mdia1-dependent and rockindependent mechanism. J Cell Biol
153:1175–1186
124. Kaverina I, Krylyshkina O, Beningo K,
Anderson K, Wang Y-L, Small JV (2002) Tensile stress stimulates microtubule outgrowth
in living cells. J Cell Sci 115:2283–2291
Mechanoregulation of PDZ Proteins
275