73. Neuman BW, Kiss G, Kunding AH, Bhella D,
Baksh MF, Connelly S, Droese B, Klaus JP,
Makino S, Sawicki SG, Siddell SG, Stamou
DG, Wilson IA, Kuhn P, Buchmeier MJ
(2011) A structural analysis of M protein in
coronavirus assembly and morphology. J Struct
Biol 174:11–22
74. DeDiego ML, Pewe L, Alvarez E, Rejas MT,
Perlman S, Enjuanes L (2008) Pathogenicity of
severe acute respiratory coronavirus deletion
mutants in hACE-2 transgenic mice. Virology
376:379–389
75. Pfefferle S, Krahling V, Ditt V, Grywna K,
Muhlberger E, Drosten C (2009) Reverse
genetic characterization of the natural genomic
deletion in SARS-coronavirus strain Frankfurt1 open reading frame 7b reveals an attenuating
function of the 7b protein in-vitro and in-vivo.
Virol J 6:131
76. DeDiego ML, Nieto-Torres JL, Jimenez-Guarden ˜o JM, Regla-Nava JA, Castan ˜oRodriguez C, Fernandez-Delgado R, Usera F,
Enjuanes L (2014) Coronavirus virulence
genes with main focus on SARS-CoV envelope
gene. Virus Res 194:124–137
77. Chung SH, Frese KK, Weiss RS, Prasad BV,
Javier RT (2007) A new crucial protein interaction element that targets the adenovirus
E4-ORF1 oncoprotein to membrane vesicles.
J Virol 81:4787–4797
78. Razanskas R, Sasnauskas K (2010) Interaction
of hepatitis B virus core protein with human
GIPC1. Arch Virol 155:247–250
79. Hsu EC, Lin YC, Hung CS, Huang CJ, Lee
MY, Yang SC, Ting LP (2007) Suppression of
hepatitis B viral gene expression by proteintyrosine phosphatase PTPN3. J Biomed Sci
14:731–744
80. Yu J, Li X, Wang Y, Li B, Li H, Li Y, Zhou W,
Zhang C, Wang Y, Rao Z, Bartlam M, Cao Y
(2011) PDlim2 selectively interacts with the
PDZ binding motif of highly pathogenic avian
H5N1 influenza A virus NS1. PLoS One 6:
e19511
81. Tomaic V, Gardiol D, Massimi P, Ozbun M,
Myers M, Banks L (2009) Human and primate
tumour viruses use PDZ binding as an evolutionarily conserved mechanism of targeting cell
polarity regulators. Oncogene 28:1–8
82. Suzuki T, Uchida-Toita M, Yoshida M (1999)
Tax protein of HTLV-1 inhibits CBP/p300mediated transcription by interfering with
recruitment of CBP/p300 onto DNA element
of E-box or p53 binding site. Oncogene
18:4137–4143
83. Wilson KC, Center DM, Cruikshank WW,
Zhang Y (2003) Binding of HTLV-1 tax oncoprotein to the precursor of interleukin-16, a T
cell PDZ domain-containing protein. Virology
306:60–67
84. Ohashi M, Sakurai M, Higuchi M, Mori N,
Fukushi M, Oie M, Coffey RJ, Yoshiura K,
Tanaka Y, Uchiyama M, Hatanaka M, Fujii M
(2004) Human T-cell leukemia virus type 1 tax
oncoprotein induces and interacts with a multiPDZ domain protein, MAGI-3. Virology
320:52–62
85. Song C, Wang W, Li M, Liu Y, Zheng D
(2009) Tax1 enhances cancer cell proliferation
via Ras-Raf-MEK-ERK signaling pathway.
IUBMB Life 61:685–692
86. Makokha GN, Takahashi M, Higuchi M,
Saito S, Tanaka Y, Fujii M (2013) Human
T-cell leukemia virus type 1 tax protein interacts with and mislocalizes the PDZ domain
protein MAGI-1. Cancer Sci 104:313–320
87. Blot V, Delamarre L, Perugi F, Pham D,
Benichou S, Benarous R, Hanada T, Chishti
AH, Dokhelar MC, Pique C (2004) Human
Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type
1 and regulates envelope mediated cell-cell
fusion in T lymphocytes. J Cell Sci
117:3983–3993
88. Chen Q, Niu X, Xu Y, Wu J, Shi Y (2007)
Solution structure and backbone dynamics of
the AF-6 PDZ domain/Bcr peptide complex.
Protein Sci 16:1053–1062
89. Belotti E, Polanowska J, Daulat AM,
Audebert S, Thome V, Lissitzky JC, Lembo F,
Blibek K, Omi S, Lenfant N, Gangar A,
Montcouquiol M, Santoni MJ, Sebbagh M,
Aurrand-Lions M, Angers S, Kodjabachian L,
Reboul J, Borg JP (2013) The human
PDZome: a gateway to PSD95-disc largezonula occludens (PDZ)-mediated functions.
Mol Cell Proteomics 12:2587–2603
236
Carlos Castan ˜ o-Rodriguez et al.
Baksh MF, Connelly S, Droese B, Klaus JP,
Makino S, Sawicki SG, Siddell SG, Stamou
DG, Wilson IA, Kuhn P, Buchmeier MJ
(2011) A structural analysis of M protein in
coronavirus assembly and morphology. J Struct
Biol 174:11–22
74. DeDiego ML, Pewe L, Alvarez E, Rejas MT,
Perlman S, Enjuanes L (2008) Pathogenicity of
severe acute respiratory coronavirus deletion
mutants in hACE-2 transgenic mice. Virology
376:379–389
75. Pfefferle S, Krahling V, Ditt V, Grywna K,
Muhlberger E, Drosten C (2009) Reverse
genetic characterization of the natural genomic
deletion in SARS-coronavirus strain Frankfurt1 open reading frame 7b reveals an attenuating
function of the 7b protein in-vitro and in-vivo.
Virol J 6:131
76. DeDiego ML, Nieto-Torres JL, Jimenez-Guarden ˜o JM, Regla-Nava JA, Castan ˜oRodriguez C, Fernandez-Delgado R, Usera F,
Enjuanes L (2014) Coronavirus virulence
genes with main focus on SARS-CoV envelope
gene. Virus Res 194:124–137
77. Chung SH, Frese KK, Weiss RS, Prasad BV,
Javier RT (2007) A new crucial protein interaction element that targets the adenovirus
E4-ORF1 oncoprotein to membrane vesicles.
J Virol 81:4787–4797
78. Razanskas R, Sasnauskas K (2010) Interaction
of hepatitis B virus core protein with human
GIPC1. Arch Virol 155:247–250
79. Hsu EC, Lin YC, Hung CS, Huang CJ, Lee
MY, Yang SC, Ting LP (2007) Suppression of
hepatitis B viral gene expression by proteintyrosine phosphatase PTPN3. J Biomed Sci
14:731–744
80. Yu J, Li X, Wang Y, Li B, Li H, Li Y, Zhou W,
Zhang C, Wang Y, Rao Z, Bartlam M, Cao Y
(2011) PDlim2 selectively interacts with the
PDZ binding motif of highly pathogenic avian
H5N1 influenza A virus NS1. PLoS One 6:
e19511
81. Tomaic V, Gardiol D, Massimi P, Ozbun M,
Myers M, Banks L (2009) Human and primate
tumour viruses use PDZ binding as an evolutionarily conserved mechanism of targeting cell
polarity regulators. Oncogene 28:1–8
82. Suzuki T, Uchida-Toita M, Yoshida M (1999)
Tax protein of HTLV-1 inhibits CBP/p300mediated transcription by interfering with
recruitment of CBP/p300 onto DNA element
of E-box or p53 binding site. Oncogene
18:4137–4143
83. Wilson KC, Center DM, Cruikshank WW,
Zhang Y (2003) Binding of HTLV-1 tax oncoprotein to the precursor of interleukin-16, a T
cell PDZ domain-containing protein. Virology
306:60–67
84. Ohashi M, Sakurai M, Higuchi M, Mori N,
Fukushi M, Oie M, Coffey RJ, Yoshiura K,
Tanaka Y, Uchiyama M, Hatanaka M, Fujii M
(2004) Human T-cell leukemia virus type 1 tax
oncoprotein induces and interacts with a multiPDZ domain protein, MAGI-3. Virology
320:52–62
85. Song C, Wang W, Li M, Liu Y, Zheng D
(2009) Tax1 enhances cancer cell proliferation
via Ras-Raf-MEK-ERK signaling pathway.
IUBMB Life 61:685–692
86. Makokha GN, Takahashi M, Higuchi M,
Saito S, Tanaka Y, Fujii M (2013) Human
T-cell leukemia virus type 1 tax protein interacts with and mislocalizes the PDZ domain
protein MAGI-1. Cancer Sci 104:313–320
87. Blot V, Delamarre L, Perugi F, Pham D,
Benichou S, Benarous R, Hanada T, Chishti
AH, Dokhelar MC, Pique C (2004) Human
Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type
1 and regulates envelope mediated cell-cell
fusion in T lymphocytes. J Cell Sci
117:3983–3993
88. Chen Q, Niu X, Xu Y, Wu J, Shi Y (2007)
Solution structure and backbone dynamics of
the AF-6 PDZ domain/Bcr peptide complex.
Protein Sci 16:1053–1062
89. Belotti E, Polanowska J, Daulat AM,
Audebert S, Thome V, Lissitzky JC, Lembo F,
Blibek K, Omi S, Lenfant N, Gangar A,
Montcouquiol M, Santoni MJ, Sebbagh M,
Aurrand-Lions M, Angers S, Kodjabachian L,
Reboul J, Borg JP (2013) The human
PDZome: a gateway to PSD95-disc largezonula occludens (PDZ)-mediated functions.
Mol Cell Proteomics 12:2587–2603
236
Carlos Castan ˜ o-Rodriguez et al.