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U (2016) Prediction of multidimensional drug
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Drugs in a curative combination therapy for
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(10):e1701881. https://doi.org/10.1126/
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A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4(2):67–73.
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108705719900400206
11. Gadagkar SR, Call GB (2015) Computational
tools for fitting the Hill equation to doseresponse curves. J Pharmacol Toxicol Methods
71:68–76. https://doi.org/10.1016/j.vascn.
2014.08.006
Efficient Measurement of Drug Interactions with DiaMOND (Diagonal. . .
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and analysis with isoboles. Curr Protoc Pharmacol 72:9.19.11–19.19.19. https://doi.org/
10.1002/0471141755.ph0919s72
4. Zimmer A, Katzir I, Dekel E, Mayo AE, Alon
U (2016) Prediction of multidimensional drug
dose responses based on measurements of drug
pairs. Proc Natl Acad Sci 113(37):10442.
https://doi.org/10.1073/pnas.1606301113
5. Russ D, Kishony R (2018) Additivity of inhibitory effects in multidrug combinations. Nat
Microbiol 3(12):1339–1345. https://doi.
org/10.1038/s41564-018-0252-1
6. Palmer AC, Chidley C, Sorger PK (2018)
Drugs in a curative combination therapy for
lymphoma exhibit low cross-resistance but
not pharmacological synergy. bioRxiv:462184.
https://doi.org/10.1101/462184
7. Cokol M, Kuru N, Bicak E, Larkins-Ford J,
Aldridge BB (2017) Efficient measurement
and factorization of high-order drug interactions in Mycobacterium tuberculosis. Sci Adv 3
(10):e1701881. https://doi.org/10.1126/
sciadv.1701881
8. Liu Q, Yin X, Languino LR, Altieri DC (2018)
Evaluation of drug combination effect using a
Bliss independence dose-response surface
model. Stat Biopharm Res 10(2):112–122.
https://doi.org/10.1080/19466315.2018.
1437071
9. Foucquier J, Guedj M (2015) Analysis of drug
combinations: current methodological landscape. Pharmacol Res Perspect 3(3):e00149.
https://doi.org/10.1002/prp2.149
10. Zhang JH, Chung TD, Oldenburg KR (1999)
A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 4(2):67–73.
https://doi.org/10.1177/
108705719900400206
11. Gadagkar SR, Call GB (2015) Computational
tools for fitting the Hill equation to doseresponse curves. J Pharmacol Toxicol Methods
71:68–76. https://doi.org/10.1016/j.vascn.
2014.08.006
Efficient Measurement of Drug Interactions with DiaMOND (Diagonal. . .
713