293
Selenium [Se, 34]
hemorrhage. Toxicity of Se is due to errors in its dosage in swine feed, which resulted
in an initial episode of diarrhea, followed by dermatological and neurological signs.
Cutaneous lesions consisted of diffuse alopecia, multifocal skin necrosis, and coronary band necrosis of the hooves. Central nervous system lesions comprised of a
severe bilateral polioencephalomalacia of the ventral horns. In general, elemental
Se is relatively nontoxic, whereas organic Se, in plants and grains, is more toxic to
livestock.
Selenium poisoning should be generally suspected, based upon a variety of clinical signs including weight loss, poor growth rates, lameness, defective hoof growth,
horizontal ridges or cracks in the hoof wall, hair loss, infertility, and acute deaths,
especially when errors are made in mixing of Se into animal feeds or overdosing
injectable Se products. A garlicky odor of the animals breath may be detected at
overdosed Se (Khan et al. 2010).
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