322
Xenopus
background infuences the dental phenotype. Cells Tissues
Organs (Print) 198, 448–456. doi:10.1159/000360157
Lin-Moshier, Y., Marchant, J.S., 2013. The Xenopus oocyte: A
single-cell model for studying Ca2+ signaling. Cold Spring
Harb. Protoc. 2013. doi:10.1101/pdb.top066308
Mandruzzato, G., Antsaklis, A., Botet, F., Chervenak, F.A., Figueras,
F., Grunebaum, A., Puerto, B., Skupski, D., Stanojevic, M.,
WAPM, 2008. Intrauterine restriction (IUGR). J. Perinat.
Med. 36, 277–281. doi:10.1515/JPM.2008.050
Manikandan, P., Nagini, S., 2018. Cytochrome P450 structure,
function and clinical signifcance: A review. Curr. Drug
Targets 19, 38–54. doi:10.2174/138945011866617012514
4557
Marchant, J.S., 2018. Heterologous protein expression in the
Xenopus oocyte. Cold Spring Harb. Protoc. 2018. doi:10.
1101/pdb.prot096990
McGraw, J., Waller, D., 2012. Cytochrome P450 variations in different ethnic populations. Expert Opin. Drug Metab. Toxicol.
8, 371–382. doi:10.1517/17425255.2012.657626
Mehdizadeh, T., Majumdar, H.D., Ahsan, S., Tavares, A.L.P.,
Moody, S.A., 2021. Mutations in SIX1 associated with
Branchio-oto-renal Syndrome (BOR) differentially affect
otic expression of putative target genes. J. Devel. Biol. 9, 25.
doi: 10.3390/jdb9030025.
Meyer, D.J., Bijlani, S., de Sautu, M., Spontarelli, K., Young, V.C.,
Gatto, C., Artigas, P., 2020. FXYD protein isoforms differentially modulate human Na/K pump function. J. Gen. Physiol.
152. doi:10.1085/jgp.202012660
Monson, C.A., Sadler, K.C., 2010. Inbreeding depression and outbreeding depression are evident in wild-type zebraf sh lines.
Zebraf sh 7, 189–197. doi:10.1089/zeb.2009.0648
Montagutelli, X., 2000. Effect of the genetic background on the
phenotype of mouse mutations. J. Am. Soc. Nephrol. 11,
Suppl 16, S101–S105.
Montgomery, S.B., Goode, D.L., Kvikstad, E., Albers, C.A.,
Zhang, Z.D., Mu, X.J., Ananda, G., Howie, B., Karczewski,
K.J., Smith, K.S., Anaya, V., Richardson, R., Davis, J., 1000
Genomes Project Consortium, MacArthur, D.G., Sidow, A.,
Duret, L., Gerstein, M., Makova, K.D., Marchini, J., Lunter,
G., 2013. The origin, evolution, and functional impact of short
insertion-deletion variants identifed in 179 human genomes.
Genome Res. 23, 749–761. doi:10.1101/gr.148718.112
Mowry, K.L., 2020. Using the Xenopus oocyte toolbox. Cold Spring
Harb. Protoc. 2020, 095844. doi:10.1101/pdb.top095844
Mullaney, J.M., Mills, R.E., Pittard, W.S., Devine, S.E., 2010.
Small insertions and deletions (INDELs) in human genomes.
Hum. Mol. Genet. 19, R131–R136. doi:10.1093/hmg/ddq400
Nashimoto, S., Yagi, S., Takeda, N., Nonaka, M., Takekuma,
Y., Sugawara, M., Sato, Y., 2020. A new system to evaluate characteristics of Niemann-Pick C1 Like 1-mediated cholesterol transport using Xenopus laevis oocytes.
Biochim. Biophys. Acta Biomembr. 183508. doi:10.1016/j.
bbamem.2020.183508
Novroski, N.M.M., Woerner, A.E., Budowle, B., 2018. Potential
highly polymorphic short tandem repeat markers for
enhanced forensic identity testing. Forensic Sci. Int. Genet.
37, 162–171. doi:10.1016/j.fsigen.2018.08.011
Ochi, H., Kawaguchi, A., Tanouchi, M., Suzuki, N., Kumada, T.,
Iwata, Y., Ogino, H., 2017a. Co-accumulation of cis-regulatory and coding mutations during the pseudogenization of
the Xenopus laevis homoeologs six6.L and six6.S. Dev. Biol.
427, 84–92. doi:10.1016/j.ydbio.2017.05.004
Ochi, H., Suzuki, N., Kawaguchi, A., Ogino, H., 2017b. Asymmetrically
reduced expression of hand1 homeologs involving a single
nucleotide substitution in a cis-regulatory element. Dev. Biol.
425, 152–160. doi:10.1016/j.ydbio.2017.03.021
Pavan, W.J., Sturm, R.A., 2019. The genetics of human skin and
hair pigmentation. Annu. Rev. Genomics Hum. Genet. 20,
41–72. doi:10.1146/annurev-genom-083118-015230
Percival, C.J., Marangoni, P., Tapaltsyan, V., Klein, O., Hallgrímsson,
B., 2017. The interaction of genetic background and mutational effects in regulation of mouse craniofacial shape. G3
(Bethesda) 7, 1439–1450. doi:10.1534/g3.117.040659
Peterson, J.R., Lebensohn, A.M., Pelish, H.E., Kirschner, M.W.,
2006. Biochemical suppression of small-molecule inhibitors:
A strategy to identify inhibitor targets and signaling pathway components. Chem. Biol. 13, 443–452. doi:10.1016/j.
chembiol.2006.02.009
Posey, J.E., 2019. Genome sequencing and implications for rare disorders. Orphanet J. Rare Dis. 14, 153. doi:10.1186/s13023019-1127-0
Rashid, K., Dannhausen, K., Langmann, T., 2019. Testing for known
retinal degeneration mutants in mouse strains. Methods Mol.
Biol. 1834, 45–58. doi:10.1007/978-1-4939-8669-9_3
Ratzan, W., Falco, R., Salanga, C., Salanga, M., Horb, M.E., 2017.
Generation of a Xenopus laevis F1 albino J strain by genome
editing and oocyte host-transfer. Dev. Biol. 426, 188–193.
doi:10.1016/j.ydbio.2016.03.006
Richard, G.-F., Kerrest, A., Dujon, B., 2008. Comparative genomics and molecular dynamics of DNA repeats in eukaryotes. Microbiol. Mol. Biol. Rev. 72, 686–727. doi:10.1128/
MMBR.00011-08
Saini, S., Mitra, I., Mousavi, N., Fotsing, S.F., Gymrek, M., 2018.
A reference haplotype panel for genome-wide imputation of
short tandem repeats. Nat. Commun. 9, 4397. doi:10.1038/
s41467-018-06694-0
Sakai, K., Ito, C., Wakabayashi, M., Kanzaki, S., Ito, T., Takada,
S., Toshimori, K., Sekita, Y., Kimura, T., 2019. Usp26 mutation in mice leads to defective spermatogenesis depending
on genetic background. Sci. Rep. 9, 13757. doi:10.1038/
s41598-019-50318-6
Saul, M.C., Philip, V.M., Reinholdt, L.G., Center for Systems
Neurogenetics of Addiction, Chesler, E.J., 2019. Highdiversity mouse populations for complex traits. Trends
Genet. 35, 501–514. doi:10.1016/j.tig.2019.04.003
Sauna, Z.E., Kimchi-Sarfaty, C., 2011. Understanding the contribution of synonymous mutations to human disease. Nat. Rev.
Genet. 12, 683–691. doi:10.1038/nrg3051
Savova, V., Pearl, E.J., Boke, E., Nag, A., Adzhubei, I., Horb,
M.E., Peshkin, L., 2017. Transcriptomic insights into genetic
diversity of protein-coding genes in X. laevis. Dev. Biol. 424,
181–188. doi:10.1016/j.ydbio.2017.02.019
Session, A.M., Uno, Y., Kwon, T., Chapman, J.A., Toyoda, A.,
Takahashi, S., Fukui, A., Hikosaka, A., Suzuki, A., Kondo,
M., van Heeringen, S.J., Quigley, I., Heinz, S., Ogino, H.,
Ochi, H., Hellsten, U., Lyons, J.B., Simakov, O., Putnam,
N., Stites, J., Rokhsar, D.S., 2016. Genome evolution in the
allotetraploid frog Xenopus laevis. Nature 538, 336–343.
doi:10.1038/nature19840
Seys, E., Andrini, O., Keck, M., Mansour-Hendili, L., Courand,
P.-Y., Simian, C., Deschenes, G., Kwon, T., Bertholet-Thomas,
A., Bobrie, G., Borde, J.S., Bourdat-Michel, G., Decramer,
S., Cailliez, M., Krug, P., Cozette, P., Delbet, J.D., Dubourg,
L., Chaveau, D., Fila, M., Vargas-Poussou, R., 2017. Clinical
and genetic spectrum of Bartter syndrome type 3. J. Am. Soc.
Nephrol. 28, 2540–2552. doi:10.1681/ASN.2016101057
Shabtai, Y., Fainsod, A., 2018. Competition between ethanol
clearance and retinoic acid biosynthesis in the induction of
Xenopus
background infuences the dental phenotype. Cells Tissues
Organs (Print) 198, 448–456. doi:10.1159/000360157
Lin-Moshier, Y., Marchant, J.S., 2013. The Xenopus oocyte: A
single-cell model for studying Ca2+ signaling. Cold Spring
Harb. Protoc. 2013. doi:10.1101/pdb.top066308
Mandruzzato, G., Antsaklis, A., Botet, F., Chervenak, F.A., Figueras,
F., Grunebaum, A., Puerto, B., Skupski, D., Stanojevic, M.,
WAPM, 2008. Intrauterine restriction (IUGR). J. Perinat.
Med. 36, 277–281. doi:10.1515/JPM.2008.050
Manikandan, P., Nagini, S., 2018. Cytochrome P450 structure,
function and clinical signifcance: A review. Curr. Drug
Targets 19, 38–54. doi:10.2174/138945011866617012514
4557
Marchant, J.S., 2018. Heterologous protein expression in the
Xenopus oocyte. Cold Spring Harb. Protoc. 2018. doi:10.
1101/pdb.prot096990
McGraw, J., Waller, D., 2012. Cytochrome P450 variations in different ethnic populations. Expert Opin. Drug Metab. Toxicol.
8, 371–382. doi:10.1517/17425255.2012.657626
Mehdizadeh, T., Majumdar, H.D., Ahsan, S., Tavares, A.L.P.,
Moody, S.A., 2021. Mutations in SIX1 associated with
Branchio-oto-renal Syndrome (BOR) differentially affect
otic expression of putative target genes. J. Devel. Biol. 9, 25.
doi: 10.3390/jdb9030025.
Meyer, D.J., Bijlani, S., de Sautu, M., Spontarelli, K., Young, V.C.,
Gatto, C., Artigas, P., 2020. FXYD protein isoforms differentially modulate human Na/K pump function. J. Gen. Physiol.
152. doi:10.1085/jgp.202012660
Monson, C.A., Sadler, K.C., 2010. Inbreeding depression and outbreeding depression are evident in wild-type zebraf sh lines.
Zebraf sh 7, 189–197. doi:10.1089/zeb.2009.0648
Montagutelli, X., 2000. Effect of the genetic background on the
phenotype of mouse mutations. J. Am. Soc. Nephrol. 11,
Suppl 16, S101–S105.
Montgomery, S.B., Goode, D.L., Kvikstad, E., Albers, C.A.,
Zhang, Z.D., Mu, X.J., Ananda, G., Howie, B., Karczewski,
K.J., Smith, K.S., Anaya, V., Richardson, R., Davis, J., 1000
Genomes Project Consortium, MacArthur, D.G., Sidow, A.,
Duret, L., Gerstein, M., Makova, K.D., Marchini, J., Lunter,
G., 2013. The origin, evolution, and functional impact of short
insertion-deletion variants identifed in 179 human genomes.
Genome Res. 23, 749–761. doi:10.1101/gr.148718.112
Mowry, K.L., 2020. Using the Xenopus oocyte toolbox. Cold Spring
Harb. Protoc. 2020, 095844. doi:10.1101/pdb.top095844
Mullaney, J.M., Mills, R.E., Pittard, W.S., Devine, S.E., 2010.
Small insertions and deletions (INDELs) in human genomes.
Hum. Mol. Genet. 19, R131–R136. doi:10.1093/hmg/ddq400
Nashimoto, S., Yagi, S., Takeda, N., Nonaka, M., Takekuma,
Y., Sugawara, M., Sato, Y., 2020. A new system to evaluate characteristics of Niemann-Pick C1 Like 1-mediated cholesterol transport using Xenopus laevis oocytes.
Biochim. Biophys. Acta Biomembr. 183508. doi:10.1016/j.
bbamem.2020.183508
Novroski, N.M.M., Woerner, A.E., Budowle, B., 2018. Potential
highly polymorphic short tandem repeat markers for
enhanced forensic identity testing. Forensic Sci. Int. Genet.
37, 162–171. doi:10.1016/j.fsigen.2018.08.011
Ochi, H., Kawaguchi, A., Tanouchi, M., Suzuki, N., Kumada, T.,
Iwata, Y., Ogino, H., 2017a. Co-accumulation of cis-regulatory and coding mutations during the pseudogenization of
the Xenopus laevis homoeologs six6.L and six6.S. Dev. Biol.
427, 84–92. doi:10.1016/j.ydbio.2017.05.004
Ochi, H., Suzuki, N., Kawaguchi, A., Ogino, H., 2017b. Asymmetrically
reduced expression of hand1 homeologs involving a single
nucleotide substitution in a cis-regulatory element. Dev. Biol.
425, 152–160. doi:10.1016/j.ydbio.2017.03.021
Pavan, W.J., Sturm, R.A., 2019. The genetics of human skin and
hair pigmentation. Annu. Rev. Genomics Hum. Genet. 20,
41–72. doi:10.1146/annurev-genom-083118-015230
Percival, C.J., Marangoni, P., Tapaltsyan, V., Klein, O., Hallgrímsson,
B., 2017. The interaction of genetic background and mutational effects in regulation of mouse craniofacial shape. G3
(Bethesda) 7, 1439–1450. doi:10.1534/g3.117.040659
Peterson, J.R., Lebensohn, A.M., Pelish, H.E., Kirschner, M.W.,
2006. Biochemical suppression of small-molecule inhibitors:
A strategy to identify inhibitor targets and signaling pathway components. Chem. Biol. 13, 443–452. doi:10.1016/j.
chembiol.2006.02.009
Posey, J.E., 2019. Genome sequencing and implications for rare disorders. Orphanet J. Rare Dis. 14, 153. doi:10.1186/s13023019-1127-0
Rashid, K., Dannhausen, K., Langmann, T., 2019. Testing for known
retinal degeneration mutants in mouse strains. Methods Mol.
Biol. 1834, 45–58. doi:10.1007/978-1-4939-8669-9_3
Ratzan, W., Falco, R., Salanga, C., Salanga, M., Horb, M.E., 2017.
Generation of a Xenopus laevis F1 albino J strain by genome
editing and oocyte host-transfer. Dev. Biol. 426, 188–193.
doi:10.1016/j.ydbio.2016.03.006
Richard, G.-F., Kerrest, A., Dujon, B., 2008. Comparative genomics and molecular dynamics of DNA repeats in eukaryotes. Microbiol. Mol. Biol. Rev. 72, 686–727. doi:10.1128/
MMBR.00011-08
Saini, S., Mitra, I., Mousavi, N., Fotsing, S.F., Gymrek, M., 2018.
A reference haplotype panel for genome-wide imputation of
short tandem repeats. Nat. Commun. 9, 4397. doi:10.1038/
s41467-018-06694-0
Sakai, K., Ito, C., Wakabayashi, M., Kanzaki, S., Ito, T., Takada,
S., Toshimori, K., Sekita, Y., Kimura, T., 2019. Usp26 mutation in mice leads to defective spermatogenesis depending
on genetic background. Sci. Rep. 9, 13757. doi:10.1038/
s41598-019-50318-6
Saul, M.C., Philip, V.M., Reinholdt, L.G., Center for Systems
Neurogenetics of Addiction, Chesler, E.J., 2019. Highdiversity mouse populations for complex traits. Trends
Genet. 35, 501–514. doi:10.1016/j.tig.2019.04.003
Sauna, Z.E., Kimchi-Sarfaty, C., 2011. Understanding the contribution of synonymous mutations to human disease. Nat. Rev.
Genet. 12, 683–691. doi:10.1038/nrg3051
Savova, V., Pearl, E.J., Boke, E., Nag, A., Adzhubei, I., Horb,
M.E., Peshkin, L., 2017. Transcriptomic insights into genetic
diversity of protein-coding genes in X. laevis. Dev. Biol. 424,
181–188. doi:10.1016/j.ydbio.2017.02.019
Session, A.M., Uno, Y., Kwon, T., Chapman, J.A., Toyoda, A.,
Takahashi, S., Fukui, A., Hikosaka, A., Suzuki, A., Kondo,
M., van Heeringen, S.J., Quigley, I., Heinz, S., Ogino, H.,
Ochi, H., Hellsten, U., Lyons, J.B., Simakov, O., Putnam,
N., Stites, J., Rokhsar, D.S., 2016. Genome evolution in the
allotetraploid frog Xenopus laevis. Nature 538, 336–343.
doi:10.1038/nature19840
Seys, E., Andrini, O., Keck, M., Mansour-Hendili, L., Courand,
P.-Y., Simian, C., Deschenes, G., Kwon, T., Bertholet-Thomas,
A., Bobrie, G., Borde, J.S., Bourdat-Michel, G., Decramer,
S., Cailliez, M., Krug, P., Cozette, P., Delbet, J.D., Dubourg,
L., Chaveau, D., Fila, M., Vargas-Poussou, R., 2017. Clinical
and genetic spectrum of Bartter syndrome type 3. J. Am. Soc.
Nephrol. 28, 2540–2552. doi:10.1681/ASN.2016101057
Shabtai, Y., Fainsod, A., 2018. Competition between ethanol
clearance and retinoic acid biosynthesis in the induction of