221
Advances in Genome Editing Tools
development in Xenopus tropicalis. The FASEB Journal 29,
385–393.
Wen, L., and Shi, Y.-B. (2015). Unliganded thyroid hormone receptor α controls developmental timing in Xenopus tropicalis.
Endocrinology 156, 721–734.
Wen, L., Shibata, Y., Su, D., Fu, L., Luu, N., and Shi, Y.-B. (2017).
Thyroid hormone receptor α controls developmental timing and regulates the rate and coordination of tissue-specif c
metamorphosis in Xenopus tropicalis. Endocrinology 158,
1985–1998.
Wen, R.H., Stanar, P., Tam, B., and Moritz, O.L. (2019). Autophagy
in Xenopus laevis rod photoreceptors is independently regulated by phototransduction and misfolded RHOP23H.
Autophagy 15, 1970–1989.
Wiechmann, A.F., Martin, T.A., and Horb, M.E. (2020). CRISPR/
Cas9 mediated mutation of the mtnr1a melatonin receptor
gene causes rod photoreceptor degeneration in developing
Xenopus tropicalis. Scientif c Reports 10, 13757.
Willsey, H.R., Walentek, P., Exner, C.R.T., Xu, Y., Lane, A.B.,
Harland, R.M., Heald, R., and Santama, N. (2018). Kataninlike protein Katnal2 is required for ciliogenesis and brain
development in Xenopus embryos. Dev Biol 442, 276–287.
Willsey, H.R., Xu, Y., Everitt, A., Dea, J., Exner, C.R.T., Willsey,
A.J., State, M.W., and Harland, R.M. (2020). The neurodevelopmental disorder risk gene DYRK1A is required for
ciliogenesis and control of brain size in Xenopus embryos.
Development 147, dev189290.
Wyatt, B.H., Raymond, T.O., Lansdon, L.A., Darbro, B.W., Murray,
J.C., Manak, J.R., and Dickinson, A.J.G. (2020). Using an
aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders. Genesis, e23394.
Yergeau, D.A., Hamlet, M.R.J., Kuliyev, E., Zhu, H., Doherty,
J.R., Archer, T.D., Subhawong, A.P., Valentine, M.B., Kelley,
C.M., and Mead, P.E. (2009). Transgenesis in Xenopus using
the Sleeping Beauty transposon system. Developmental
Dynamics: An Offcial Publication of the American
Association of Anatomists 238, 1727–1743.
Yergeau, D.A., Kelley, C.M., Kuliyev, E., Zhu, H., Hamlet,
M.R.J., Sater, A.K., Wells, D.E., and Mead, P.E. (2011a).
Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis. Mobile Dna-Uk 2, 15.
Yergeau, D.A., Kelley, C.M., Kuliyev, E., Zhu, H., Hamlet,
M.R.J., Sater, A.K., Wells, D.E., and Mead, P.E. (2011b).
Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis. Mobile DNA 2, 15.
Yergeau, D.A., Kelley, C.M., Zhu, H., Kuliyev, E., and Mead, P.E.
(2010). Transposon transgenesis in Xenopus. Methods (San
Diego, Calif.) 51, 92–100.
Yergeau, D.A., Kelley, C.M., Zhu, H., Kuliyev, E., and Mead,
P.E. (2012). Xenopus protocols, post-genomic approaches.
Methods Mol Biology 917, 111–127.
Young, J.J., Cherone, J.M., Doyon, Y., Ankoudinova, I., Faraji,
F.M., Lee, A.H., Ngo, C., Guschin, D.Y., Paschon, D.E.,
Miller, J.C., et al. (2011). Effcient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-fnger nucleases. Proceedings
of the National Academy of Sciences of the United States of
America 108, 7052–7057.
Young, J.J., Kjolby, R.A.S., Wu, G., Wong, D., Hsu, S., and
Harland, R.M. (2017). Noggin is required for f rst pharyngeal arch differentiation in the frog Xenopus tropicalis. Dev
Biol 426, 245–254.
Zhang, T., Guo, X., and Chen, Y. (2013). Retinoic acid-activated
Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus
pancreas, oesophagus, stomach, and duodenum specif cation.
PLoS ONE 8, e65058.
Advances in Genome Editing Tools
development in Xenopus tropicalis. The FASEB Journal 29,
385–393.
Wen, L., and Shi, Y.-B. (2015). Unliganded thyroid hormone receptor α controls developmental timing in Xenopus tropicalis.
Endocrinology 156, 721–734.
Wen, L., Shibata, Y., Su, D., Fu, L., Luu, N., and Shi, Y.-B. (2017).
Thyroid hormone receptor α controls developmental timing and regulates the rate and coordination of tissue-specif c
metamorphosis in Xenopus tropicalis. Endocrinology 158,
1985–1998.
Wen, R.H., Stanar, P., Tam, B., and Moritz, O.L. (2019). Autophagy
in Xenopus laevis rod photoreceptors is independently regulated by phototransduction and misfolded RHOP23H.
Autophagy 15, 1970–1989.
Wiechmann, A.F., Martin, T.A., and Horb, M.E. (2020). CRISPR/
Cas9 mediated mutation of the mtnr1a melatonin receptor
gene causes rod photoreceptor degeneration in developing
Xenopus tropicalis. Scientif c Reports 10, 13757.
Willsey, H.R., Walentek, P., Exner, C.R.T., Xu, Y., Lane, A.B.,
Harland, R.M., Heald, R., and Santama, N. (2018). Kataninlike protein Katnal2 is required for ciliogenesis and brain
development in Xenopus embryos. Dev Biol 442, 276–287.
Willsey, H.R., Xu, Y., Everitt, A., Dea, J., Exner, C.R.T., Willsey,
A.J., State, M.W., and Harland, R.M. (2020). The neurodevelopmental disorder risk gene DYRK1A is required for
ciliogenesis and control of brain size in Xenopus embryos.
Development 147, dev189290.
Wyatt, B.H., Raymond, T.O., Lansdon, L.A., Darbro, B.W., Murray,
J.C., Manak, J.R., and Dickinson, A.J.G. (2020). Using an
aquatic model, Xenopus laevis, to uncover the role of chromodomain 1 in craniofacial disorders. Genesis, e23394.
Yergeau, D.A., Hamlet, M.R.J., Kuliyev, E., Zhu, H., Doherty,
J.R., Archer, T.D., Subhawong, A.P., Valentine, M.B., Kelley,
C.M., and Mead, P.E. (2009). Transgenesis in Xenopus using
the Sleeping Beauty transposon system. Developmental
Dynamics: An Offcial Publication of the American
Association of Anatomists 238, 1727–1743.
Yergeau, D.A., Kelley, C.M., Kuliyev, E., Zhu, H., Hamlet,
M.R.J., Sater, A.K., Wells, D.E., and Mead, P.E. (2011a).
Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis. Mobile Dna-Uk 2, 15.
Yergeau, D.A., Kelley, C.M., Kuliyev, E., Zhu, H., Hamlet,
M.R.J., Sater, A.K., Wells, D.E., and Mead, P.E. (2011b).
Remobilization of Sleeping Beauty transposons in the germline of Xenopus tropicalis. Mobile DNA 2, 15.
Yergeau, D.A., Kelley, C.M., Zhu, H., Kuliyev, E., and Mead, P.E.
(2010). Transposon transgenesis in Xenopus. Methods (San
Diego, Calif.) 51, 92–100.
Yergeau, D.A., Kelley, C.M., Zhu, H., Kuliyev, E., and Mead,
P.E. (2012). Xenopus protocols, post-genomic approaches.
Methods Mol Biology 917, 111–127.
Young, J.J., Cherone, J.M., Doyon, Y., Ankoudinova, I., Faraji,
F.M., Lee, A.H., Ngo, C., Guschin, D.Y., Paschon, D.E.,
Miller, J.C., et al. (2011). Effcient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-fnger nucleases. Proceedings
of the National Academy of Sciences of the United States of
America 108, 7052–7057.
Young, J.J., Kjolby, R.A.S., Wu, G., Wong, D., Hsu, S., and
Harland, R.M. (2017). Noggin is required for f rst pharyngeal arch differentiation in the frog Xenopus tropicalis. Dev
Biol 426, 245–254.
Zhang, T., Guo, X., and Chen, Y. (2013). Retinoic acid-activated
Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus
pancreas, oesophagus, stomach, and duodenum specif cation.
PLoS ONE 8, e65058.