120
Xenopus
interacts with Groucho/TLE in Xenopus. Int. J. Dev. Biol.
50, 473–479. https://doi.org/10.1387/ijdb.052138ak
Kondow, A., Hitachi, K., Okabayashi, K., Hayashi, N., Asashima,
M., 2007. Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis
in Xenopus. Biochem. Biophys. Res. Commun. 359, 959–
964. https://doi.org/10.1016/j.bbrc.2007.05.211
Kopan, R., Ilagan, M.X.G., 2009. The canonical Notch signaling
pathway: Unfolding the activation mechanism. Cell 137,
216–233. https://doi.org/10.1016/j.cell.2009.03.045
Kopan, R., Nye, J.S., Weintraub, H., 1994. The intracellular
domain of mouse Notch: A constitutively activated repressor
of myogenesis directed at the basic helix-loop-helix region of
MyoD. Development 120, 2385–2396.
Kovall, R.A., Blacklow, S.C., 2010. Mechanistic insights into Notch
receptor signaling from structural and biochemical studies.
Curr. Top. Dev. Biol. 92, 31–71. https://doi.org/10.1016/
S0070-2153(10)92002-4
Koyano-Nakagawa, N., Kim, J., Anderson, D., Kintner, C., 2000.
Hes6 acts in a positive feedback loop with the neurogenins to
promote neuronal differentiation. Development 127, 4203–
4216.
Kurata, T., Ueno, N., 2003. Xenopus Nbx, a novel NK-1 related
gene essential for neural crest formation. Dev. Biol. 257,
30–40. https://doi.org/10.1016/s0012-1606(03)00060-5
Kuriyama, S., Lupo, G., Ohta, K., Ohnuma, S., Harris, W.A.,
Tanaka, H., 2006. Tsukushi controls ectodermal patterning
and neural crest specifcation in Xenopus by direct regulation
of BMP4 and X-delta-1 activity. Development 133, 75–88.
https://doi.org/10.1242/dev.02178
Kuroda, H., Wessely, O., De Robertis, E.M., 2004. Neural induction in Xenopus: Requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and
Cerberus. PLoS Biol. 2, E92. https://doi.org/10.1371/journal.
pbio.0020092
Kwon, C., Cheng, P., King, I.N., Andersen, P., Shenje, L., Nigam,
V., Srivastava, D., 2011. Notch post-translationally regulates
β-catenin protein in stem and progenitor cells. Nat. Cell Biol.
13, 1244–1251. https://doi.org/10.1038/ncb2313
Lahaye, K., Kricha, S., Bellefroid, E.J., 2002. XNAP, a conserved ankyrin repeat-containing protein with a role in
the Notch pathway during Xenopus primary neurogenesis. Mech. Dev. 110, 113–124. https://doi.org/10.1016/
S0925-4773(01)00570-6
Lai, E.C., 2004. Notch signaling: Control of cell communication and cell fate. Development 131, 965–973. https://doi.
org/10.1242/dev.01074
Lamar, E., Deblandre, G., Wettstein, D., Gawantka, V., Pollet, N.,
Niehrs, C., Kintner, C., 2001. Nrarp is a novel intracellular
component of the Notch signaling pathway. Genes Dev. 15,
1885–1899. https://doi.org/10.1101/gad.908101
Lamar, E., Kintner, C., 2005. The Notch targets Esr1 and Esr10
are differentially regulated in Xenopus neural precursors.
Development 132, 3619–3630. https://doi.org/10.1242/dev.
01937
Layden, M.J., Martindale, M.Q., 2014. Non-canonical Notch
signaling represents an ancestral mechanism to regulate neural differentiation. Evodevo 5, 30. https://doi.org/
10.1186/2041-9139-5-30
Lee, J., Platt, K.A., Censullo, P., Ruiz i Altaba, A., 1997. Gli1 is
a target of Sonic hedgehog that induces ventral neural tube
development. Development 124, 2537–2552.
Lehmann, R., Jiménez, F., Dietrich, U., Campos-Ortega, J.A.,
1983. On the phenotype and development of mutants of
early neurogenesis in Drosophila melanogaster: Wilhelm
Roux’s Arch. Dev. Biol. 192, 62–74. https://doi.org/10.1007/
BF00848482
Leung, A., Ciau-Uitz, A., Pinheiro, P., Monteiro, R., Zuo, J., Vyas,
P., Patient, R., Porcher, C., 2013. Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specif cation. Dev. Cell 24, 144–158. https://doi.org/10.1016/j.
devcel.2012.12.004
Lewis, J., 1998. Notch signalling and the control of cell fate choices
in vertebrates. Semin. Cell Dev. Biol. 9, 583–589. https://doi.
org/10.1006/scdb.1998.0266
Li, Y., Fenger, U., Niehrs, C., Pollet, N., 2003. Cyclic expression of
esr9 gene in Xenopus presomitic mesoderm.Differentiation71,
83–89. https://doi.org/10.1046/j.1432-0436.2003.700608.x
López, S.L., Carrasco, A.E., 2006. Sonic hedgehog signalling in dorsal midline and neural development. In: Fisher,
C.E., Howie, S.E.M. (Eds.), Shh and Gli Signalling and
Development. Landes Biosciences and Springer New York,
New York, NY, pp. 12–22.
López, S.L., Paganelli, A.R., Rosato Siri, M. V, Ocaña, O.H.,
Franco, P.G., Carrasco, A.E., 2003. Notch activates Sonic
hedgehog and both are involved in the specifcation of dorsal
midline cell-fates in Xenopus. Development 130, 2225–2238.
https://doi.org/10.1242/dev.00443
López, S.L., Rosato-Siri, M. V, Franco, P.G., Paganelli, A.R.,
Carrasco, A.E., 2005. The Notch-target gene hairy2a impedes
the involution of notochordal cells by promoting f oor plate
fates in Xenopus embryos. Development 132, 1035–1046.
https://doi.org/10.1242/dev.01659
Ma, Q., Kintner, C., Anderson, D.J., 1996. Identifcation of neurogenin, a vertebrate neuronal determination gene. Cell 87, 43–52.
Maguire, R.J., Isaacs, H. V., Pownall, M.E., 2012. Early transcriptional targets of MyoD link myogenesis and somitogenesis. Dev. Biol. 371, 256–268. https://doi.org/10.1016/j.
ydbio.2012.08.027
Maharana, S.K., Schlosser, G., 2018. A gene regulatory network underlying the formation of pre-placodal ectoderm in
Xenopus laevis. BMC Biol. 16, 79. https://doi.org/10.1186/
s12915-018-0540-5
Marcet, B., Chevalier, B., Luxardi, G., Coraux, C., Zaragosi, L.-E.,
Cibois, M., Robbe-Sermesant, K., Jolly, T., Cardinaud, B.,
Moreilhon, C., Giovannini-Chami, L., Nawrocki-Raby, B.,
Birembaut, P., Waldmann, R., Kodjabachian, L., Barbry, P.,
2011. Control of vertebrate multiciliogenesis by miR-449
through direct repression of the Delta/Notch pathway. Nat.
Cell Biol. 13, 694–701. https://doi.org/10.1038/ncb2241
Marine, J.-C., Bellefroid, J.E., Pendeville, H., Martial, J.A., Pieler,
T., 1997. A role for Xenopus Gli-type zinc f nger proteins
in the early embryonic patterning of mesoderm and neuroectoderm. Mech. Dev. 63, 211–225. https://doi.org/10.1016/
S0925-4773(97)00050-6
McLaughlin, K.A., Rones, M.S., Mercola, M., 2000. Notch regulates cell fate in the developing pronephros. Dev. Biol. 227,
567–580. https://doi.org/10.1006/dbio.2000.9913
Meier-Stiegen, F., Schwanbeck, R., Bernoth, K., Martini, S.,
Hieronymus, T., Ruau, D., Zenke, M., Just, U., 2010.
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage
determinants and inhibitors. PLoS One 5, e11481. https://doi.
org/10.1371/journal.pone.0011481
Miazga, C.M., McLaughlin, K.A., 2009. Coordinating the timing
of cardiac precursor development during gastrulation: A new
role for Notch signaling. Dev. Biol. 333, 285–296. https://doi.
org/10.1016/j.ydbio.2009.06.040
Michiue, T., Yamamoto, T., Yasuoka, Y., Goto, T., Ikeda, T., Nagura,
K., Nakayama, T., Taira, M., Kinoshita, T., 2017. High
Xenopus
interacts with Groucho/TLE in Xenopus. Int. J. Dev. Biol.
50, 473–479. https://doi.org/10.1387/ijdb.052138ak
Kondow, A., Hitachi, K., Okabayashi, K., Hayashi, N., Asashima,
M., 2007. Bowline mediates association of the transcriptional corepressor XGrg-4 with Tbx6 during somitogenesis
in Xenopus. Biochem. Biophys. Res. Commun. 359, 959–
964. https://doi.org/10.1016/j.bbrc.2007.05.211
Kopan, R., Ilagan, M.X.G., 2009. The canonical Notch signaling
pathway: Unfolding the activation mechanism. Cell 137,
216–233. https://doi.org/10.1016/j.cell.2009.03.045
Kopan, R., Nye, J.S., Weintraub, H., 1994. The intracellular
domain of mouse Notch: A constitutively activated repressor
of myogenesis directed at the basic helix-loop-helix region of
MyoD. Development 120, 2385–2396.
Kovall, R.A., Blacklow, S.C., 2010. Mechanistic insights into Notch
receptor signaling from structural and biochemical studies.
Curr. Top. Dev. Biol. 92, 31–71. https://doi.org/10.1016/
S0070-2153(10)92002-4
Koyano-Nakagawa, N., Kim, J., Anderson, D., Kintner, C., 2000.
Hes6 acts in a positive feedback loop with the neurogenins to
promote neuronal differentiation. Development 127, 4203–
4216.
Kurata, T., Ueno, N., 2003. Xenopus Nbx, a novel NK-1 related
gene essential for neural crest formation. Dev. Biol. 257,
30–40. https://doi.org/10.1016/s0012-1606(03)00060-5
Kuriyama, S., Lupo, G., Ohta, K., Ohnuma, S., Harris, W.A.,
Tanaka, H., 2006. Tsukushi controls ectodermal patterning
and neural crest specifcation in Xenopus by direct regulation
of BMP4 and X-delta-1 activity. Development 133, 75–88.
https://doi.org/10.1242/dev.02178
Kuroda, H., Wessely, O., De Robertis, E.M., 2004. Neural induction in Xenopus: Requirement for ectodermal and endomesodermal signals via Chordin, Noggin, beta-Catenin, and
Cerberus. PLoS Biol. 2, E92. https://doi.org/10.1371/journal.
pbio.0020092
Kwon, C., Cheng, P., King, I.N., Andersen, P., Shenje, L., Nigam,
V., Srivastava, D., 2011. Notch post-translationally regulates
β-catenin protein in stem and progenitor cells. Nat. Cell Biol.
13, 1244–1251. https://doi.org/10.1038/ncb2313
Lahaye, K., Kricha, S., Bellefroid, E.J., 2002. XNAP, a conserved ankyrin repeat-containing protein with a role in
the Notch pathway during Xenopus primary neurogenesis. Mech. Dev. 110, 113–124. https://doi.org/10.1016/
S0925-4773(01)00570-6
Lai, E.C., 2004. Notch signaling: Control of cell communication and cell fate. Development 131, 965–973. https://doi.
org/10.1242/dev.01074
Lamar, E., Deblandre, G., Wettstein, D., Gawantka, V., Pollet, N.,
Niehrs, C., Kintner, C., 2001. Nrarp is a novel intracellular
component of the Notch signaling pathway. Genes Dev. 15,
1885–1899. https://doi.org/10.1101/gad.908101
Lamar, E., Kintner, C., 2005. The Notch targets Esr1 and Esr10
are differentially regulated in Xenopus neural precursors.
Development 132, 3619–3630. https://doi.org/10.1242/dev.
01937
Layden, M.J., Martindale, M.Q., 2014. Non-canonical Notch
signaling represents an ancestral mechanism to regulate neural differentiation. Evodevo 5, 30. https://doi.org/
10.1186/2041-9139-5-30
Lee, J., Platt, K.A., Censullo, P., Ruiz i Altaba, A., 1997. Gli1 is
a target of Sonic hedgehog that induces ventral neural tube
development. Development 124, 2537–2552.
Lehmann, R., Jiménez, F., Dietrich, U., Campos-Ortega, J.A.,
1983. On the phenotype and development of mutants of
early neurogenesis in Drosophila melanogaster: Wilhelm
Roux’s Arch. Dev. Biol. 192, 62–74. https://doi.org/10.1007/
BF00848482
Leung, A., Ciau-Uitz, A., Pinheiro, P., Monteiro, R., Zuo, J., Vyas,
P., Patient, R., Porcher, C., 2013. Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specif cation. Dev. Cell 24, 144–158. https://doi.org/10.1016/j.
devcel.2012.12.004
Lewis, J., 1998. Notch signalling and the control of cell fate choices
in vertebrates. Semin. Cell Dev. Biol. 9, 583–589. https://doi.
org/10.1006/scdb.1998.0266
Li, Y., Fenger, U., Niehrs, C., Pollet, N., 2003. Cyclic expression of
esr9 gene in Xenopus presomitic mesoderm.Differentiation71,
83–89. https://doi.org/10.1046/j.1432-0436.2003.700608.x
López, S.L., Carrasco, A.E., 2006. Sonic hedgehog signalling in dorsal midline and neural development. In: Fisher,
C.E., Howie, S.E.M. (Eds.), Shh and Gli Signalling and
Development. Landes Biosciences and Springer New York,
New York, NY, pp. 12–22.
López, S.L., Paganelli, A.R., Rosato Siri, M. V, Ocaña, O.H.,
Franco, P.G., Carrasco, A.E., 2003. Notch activates Sonic
hedgehog and both are involved in the specifcation of dorsal
midline cell-fates in Xenopus. Development 130, 2225–2238.
https://doi.org/10.1242/dev.00443
López, S.L., Rosato-Siri, M. V, Franco, P.G., Paganelli, A.R.,
Carrasco, A.E., 2005. The Notch-target gene hairy2a impedes
the involution of notochordal cells by promoting f oor plate
fates in Xenopus embryos. Development 132, 1035–1046.
https://doi.org/10.1242/dev.01659
Ma, Q., Kintner, C., Anderson, D.J., 1996. Identifcation of neurogenin, a vertebrate neuronal determination gene. Cell 87, 43–52.
Maguire, R.J., Isaacs, H. V., Pownall, M.E., 2012. Early transcriptional targets of MyoD link myogenesis and somitogenesis. Dev. Biol. 371, 256–268. https://doi.org/10.1016/j.
ydbio.2012.08.027
Maharana, S.K., Schlosser, G., 2018. A gene regulatory network underlying the formation of pre-placodal ectoderm in
Xenopus laevis. BMC Biol. 16, 79. https://doi.org/10.1186/
s12915-018-0540-5
Marcet, B., Chevalier, B., Luxardi, G., Coraux, C., Zaragosi, L.-E.,
Cibois, M., Robbe-Sermesant, K., Jolly, T., Cardinaud, B.,
Moreilhon, C., Giovannini-Chami, L., Nawrocki-Raby, B.,
Birembaut, P., Waldmann, R., Kodjabachian, L., Barbry, P.,
2011. Control of vertebrate multiciliogenesis by miR-449
through direct repression of the Delta/Notch pathway. Nat.
Cell Biol. 13, 694–701. https://doi.org/10.1038/ncb2241
Marine, J.-C., Bellefroid, J.E., Pendeville, H., Martial, J.A., Pieler,
T., 1997. A role for Xenopus Gli-type zinc f nger proteins
in the early embryonic patterning of mesoderm and neuroectoderm. Mech. Dev. 63, 211–225. https://doi.org/10.1016/
S0925-4773(97)00050-6
McLaughlin, K.A., Rones, M.S., Mercola, M., 2000. Notch regulates cell fate in the developing pronephros. Dev. Biol. 227,
567–580. https://doi.org/10.1006/dbio.2000.9913
Meier-Stiegen, F., Schwanbeck, R., Bernoth, K., Martini, S.,
Hieronymus, T., Ruau, D., Zenke, M., Just, U., 2010.
Activated Notch1 target genes during embryonic cell differentiation depend on the cellular context and include lineage
determinants and inhibitors. PLoS One 5, e11481. https://doi.
org/10.1371/journal.pone.0011481
Miazga, C.M., McLaughlin, K.A., 2009. Coordinating the timing
of cardiac precursor development during gastrulation: A new
role for Notch signaling. Dev. Biol. 333, 285–296. https://doi.
org/10.1016/j.ydbio.2009.06.040
Michiue, T., Yamamoto, T., Yasuoka, Y., Goto, T., Ikeda, T., Nagura,
K., Nakayama, T., Taira, M., Kinoshita, T., 2017. High