H2O
nadh2
0
II
ch3-c-cooh
acide pyruvique
COOH
HC-OH
I
CH
CoASH
CO2
NADH2
— NAD
décarboxylation oxydative
CH3-C-S-C0A
acétyl-coenzyme A
H20
CoASH
COOH
C=O
ch2
NAD
j
CD enzyme de
condensation
acide
oxaloacétique
acide malique
® fumarase
COOH
COOH
CH
COOH
'2
HO-C-COOH
CH2
COOH
COOH
(2) aconitase
~ (§)malatedéshydrogénase
acide citrique
CH
H-C-COOH
H-C-OH
COOH
(3) isocitricodéshydrogénase
COOH
acide isocitrique
NADP
NADPHj
CH
COOH
ch2
acide fumarique
(7) succinodéshydrogénase
COOH
fadh2
FAD
CH
acide
. -
oxalosuccinique H-C-COOH
c=o
CH2
COOH
CO;
NADH2