Biomarkers
Phospholipid fatty acid composition of nine
marine sponges from Qatar
J.-M. Njinkoué
(1) , G. Barnathan
(1) , A.R. Al Muftah
(2) ,
H. Al Aeasa
(2) , J. Vacelet
( 3) , J.-M. Kornprobst
(1)
(1) Faculté de pharmacie, groupe SMAB, ISOMer, laboratoire de chimie marine,
1 rue Gaston Veil, BP 1024, 44035 Nantes Cedex 01, France
(2) University of Qatar, faculty of Sciences, Doha, Qatar
(3) Centre d’océanologie, station marine d’Endoume, rue de la Batterie des Lions, case 901,
13288 Marseille Cedex 9, France
Abstract
Phospholipid fatty acid composition was studied in sponges from Qatar,
including eight Demospongia and one Calcarea. More than 60 fatty acids
were identified in each species as methyl esters and N-acyl pyrrolidides by gas chromatography-mass spectrometry. Twenty-two typical
A5,9 fatty acids were identified (C16 to C28), including two brominated acids. An unusual level (68%) of Δ5,9 fatty acids was found in
Dysidea sp. A new fatty acid was identified, namely l4-methyl-5,9heptadecadienoic acid. Six unusual C18 and C20 acids were identified
with the Δ5,9, Δ6,l1 and Δ7,l 3 unsaturations.
Résumé
La composition en acides gras des phospholipides a été étudiée chez des
éponges du Qatar, huit Demospongia, une Calcarea. Plus de soixante acides
gras ont été identifiés dans chaque espèce, à l’état d’esters méthyliques
et de N-acyl pyrrolidides, par chromatographie gazeuse-spectrométrie
de masse. Vingt-deux acides gras typiques avec insaturation Δ5,9 (C16
à C28) ont été identifiés comprenant deux acides bromés. Un taux
exceptionnel (68 %) d’acides gras A5,9 a été trouvé chez Dysidea sp. Un
nouvel acide a été identifié, l’acide l4-méthyl-5,9-heptadécadiénoïque.
Six acides inhabituels ont été identifiés, en 08 et C20, avec les insaturations Δ5,9, Δ6,11 et Δ7,13.
Introduction
Sponges are known to be a rich source of very long-chain phospholipid
fatty acids with unusual branching and unsaturation patterns. Although
a number of sponges have been studied for their lipids in various areas
in the world, there is no report on lipids from sponges originating
from the Arabian Gulf (Djerassi & Lam, 1991; Carballeira & Maldonado, 1989; Barnathan et al., 1996). Moreover, a few studies have been
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Phospholipid fatty acid composition of nine
marine sponges from Qatar
J.-M. Njinkoué
(1) , G. Barnathan
(1) , A.R. Al Muftah
(2) ,
H. Al Aeasa
(2) , J. Vacelet
( 3) , J.-M. Kornprobst
(1)
(1) Faculté de pharmacie, groupe SMAB, ISOMer, laboratoire de chimie marine,
1 rue Gaston Veil, BP 1024, 44035 Nantes Cedex 01, France
(2) University of Qatar, faculty of Sciences, Doha, Qatar
(3) Centre d’océanologie, station marine d’Endoume, rue de la Batterie des Lions, case 901,
13288 Marseille Cedex 9, France
Abstract
Phospholipid fatty acid composition was studied in sponges from Qatar,
including eight Demospongia and one Calcarea. More than 60 fatty acids
were identified in each species as methyl esters and N-acyl pyrrolidides by gas chromatography-mass spectrometry. Twenty-two typical
A5,9 fatty acids were identified (C16 to C28), including two brominated acids. An unusual level (68%) of Δ5,9 fatty acids was found in
Dysidea sp. A new fatty acid was identified, namely l4-methyl-5,9heptadecadienoic acid. Six unusual C18 and C20 acids were identified
with the Δ5,9, Δ6,l1 and Δ7,l 3 unsaturations.
Résumé
La composition en acides gras des phospholipides a été étudiée chez des
éponges du Qatar, huit Demospongia, une Calcarea. Plus de soixante acides
gras ont été identifiés dans chaque espèce, à l’état d’esters méthyliques
et de N-acyl pyrrolidides, par chromatographie gazeuse-spectrométrie
de masse. Vingt-deux acides gras typiques avec insaturation Δ5,9 (C16
à C28) ont été identifiés comprenant deux acides bromés. Un taux
exceptionnel (68 %) d’acides gras A5,9 a été trouvé chez Dysidea sp. Un
nouvel acide a été identifié, l’acide l4-méthyl-5,9-heptadécadiénoïque.
Six acides inhabituels ont été identifiés, en 08 et C20, avec les insaturations Δ5,9, Δ6,11 et Δ7,13.
Introduction
Sponges are known to be a rich source of very long-chain phospholipid
fatty acids with unusual branching and unsaturation patterns. Although
a number of sponges have been studied for their lipids in various areas
in the world, there is no report on lipids from sponges originating
from the Arabian Gulf (Djerassi & Lam, 1991; Carballeira & Maldonado, 1989; Barnathan et al., 1996). Moreover, a few studies have been
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