Biomarkers
Fatty acids from marine organisms:
recent research developments
Gilles Barnathan, Jean-Michel Kornprobst
Faculté de pharmacie, groupe SMAB, ISOMer, laboratoire de chimie marine, 1 rue Gaston Veil,
BP 1024, 44035 Nantes Cedex 01, France.
Abstract
This paper reports on the phospholipid fatty acid composition of marine
sponges, especially those with the typical A5,9 system, as well as the
fatty acid composition of gorgonians. The first results of sponge glycosphingolipids and the identification of new mid-chain methoxylated
fatty acids in lipids of a red alga are also reported. This overview concerns
some of our results during the last five years in terms of the structural
elucidation of several new compounds and their possible implications
in biosynthetic relationships and as biomarkers for chemotaxonomic
purposes.
Résumé
La composition en acides gras des phospholipides d’éponges marines,
en particulier ceux à système A5,9 typique, et en acides gras de gorgones, est rapportée. Les premiers résultats sur les glycosphingolipides
d’éponges sont présentés. De nouveaux acides gras méthoxylés en milieu
de chaîne ont été identifiés dans les lipides d’une algue rouge. Cette
présentation reprend certains de nos résultats de ces cinq dernières
années en termes de caractérisation structurale de plusieurs composés
nouveaux, de leurs implications dans les processus biosynthétiques, de
leur possible utilité comme biomarqueurs chimiotaxonomiques.
Introduction
The interest of chemists in lipids from marine animals and microalgae
has been stimulated, in particular, by the recognition that polyunsaturated fatty acids are important to human health and nutrition. The
rapid development of excellent analytical methods, especially gas-liquid
chromatography coupled to mass spectrometry (GC/MS), has also been
a major contributing factor.
Marine invertebrates, especially marine sponges, have proved to be a
rich source of many unusual phospholipid fatty acids. Sponges are very
ancient animals with special structural features, particularly the cell membrane, which have allowed their adaptation to often precarious environments.
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Fatty acids from marine organisms:
recent research developments
Gilles Barnathan, Jean-Michel Kornprobst
Faculté de pharmacie, groupe SMAB, ISOMer, laboratoire de chimie marine, 1 rue Gaston Veil,
BP 1024, 44035 Nantes Cedex 01, France.
Abstract
This paper reports on the phospholipid fatty acid composition of marine
sponges, especially those with the typical A5,9 system, as well as the
fatty acid composition of gorgonians. The first results of sponge glycosphingolipids and the identification of new mid-chain methoxylated
fatty acids in lipids of a red alga are also reported. This overview concerns
some of our results during the last five years in terms of the structural
elucidation of several new compounds and their possible implications
in biosynthetic relationships and as biomarkers for chemotaxonomic
purposes.
Résumé
La composition en acides gras des phospholipides d’éponges marines,
en particulier ceux à système A5,9 typique, et en acides gras de gorgones, est rapportée. Les premiers résultats sur les glycosphingolipides
d’éponges sont présentés. De nouveaux acides gras méthoxylés en milieu
de chaîne ont été identifiés dans les lipides d’une algue rouge. Cette
présentation reprend certains de nos résultats de ces cinq dernières
années en termes de caractérisation structurale de plusieurs composés
nouveaux, de leurs implications dans les processus biosynthétiques, de
leur possible utilité comme biomarqueurs chimiotaxonomiques.
Introduction
The interest of chemists in lipids from marine animals and microalgae
has been stimulated, in particular, by the recognition that polyunsaturated fatty acids are important to human health and nutrition. The
rapid development of excellent analytical methods, especially gas-liquid
chromatography coupled to mass spectrometry (GC/MS), has also been
a major contributing factor.
Marine invertebrates, especially marine sponges, have proved to be a
rich source of many unusual phospholipid fatty acids. Sponges are very
ancient animals with special structural features, particularly the cell membrane, which have allowed their adaptation to often precarious environments.
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