12. IMMUNOLOGY OF FISH
483
ulus have also been studied extensively by Goss and his associates (references in Hildemann and Cooper, 1963).
Triplett and Barrymore ( 1960) have investigated the ontogenic appearance of transplant rejection in the shiner sea perch, Cymtogaster
aggregata, a viviparous embiotocid. They have shown that embryos
accept scale transplants, but reject homografts, starting one to three days
following birth. The potential experimental value of this group of
fishes demonstrated by their work has yet to be taken advantage of by
other investigators. Reid and Triplett (19S8) report observations on
some initial autograft destruction in scale transplants in Micrqterus
salmoides and relate their recovery to a lag period observed in homograft destruction.
Finally, it is to be noted that fin transplants have been studied by
Kallman and Gordon (1958) in the viviparous platyfish, Xiphophorus
mculatus, taking advantage of crosses obtained from inbred strains.
The results of this work show that histocompatibility differences occur
according to the same genetic relationships observed in mammals. That
is, isografts and those from parent to F, hybrid offspring were completely accepted, while reciprocal grafts or those among parents and
F, offspring were rejected as expected.
Kallman has shown the potential usefulness of fin transplants in
evaluating the degree of genetic homogeneity of small isolated fish
populations (1961), and Hildemann (1962) has pointed out the potential
usefulness of scale transplants in subpopulations analogous to those
conducted on amphibians ( Hildemann and Haas, 1961).
Ball and Kallman (1962) also report the success of whole pituitary
transplants into the tail musculature of adults of the all-female, gynogenetic teleost, Molliensiu formosa. This experiment is noted because
it is representative of the area of transplantation so well exploited,
especially in amphibians, by embryologists, and it is concerned with
discovering aspects of physiology other than those that are the subject
of this chapter.
IV. COMPLEMENT
Early immunologists soon discovered that the fresh normal serum
of humans and laboratory animals contained a system of molecules that
worked together to lyse red blood cells (and some bacteria) to which
specific antibodies were attached. The system has come to be called
“complement” (symbolized C’ ) . Some of its components are inactivated
483
ulus have also been studied extensively by Goss and his associates (references in Hildemann and Cooper, 1963).
Triplett and Barrymore ( 1960) have investigated the ontogenic appearance of transplant rejection in the shiner sea perch, Cymtogaster
aggregata, a viviparous embiotocid. They have shown that embryos
accept scale transplants, but reject homografts, starting one to three days
following birth. The potential experimental value of this group of
fishes demonstrated by their work has yet to be taken advantage of by
other investigators. Reid and Triplett (19S8) report observations on
some initial autograft destruction in scale transplants in Micrqterus
salmoides and relate their recovery to a lag period observed in homograft destruction.
Finally, it is to be noted that fin transplants have been studied by
Kallman and Gordon (1958) in the viviparous platyfish, Xiphophorus
mculatus, taking advantage of crosses obtained from inbred strains.
The results of this work show that histocompatibility differences occur
according to the same genetic relationships observed in mammals. That
is, isografts and those from parent to F, hybrid offspring were completely accepted, while reciprocal grafts or those among parents and
F, offspring were rejected as expected.
Kallman has shown the potential usefulness of fin transplants in
evaluating the degree of genetic homogeneity of small isolated fish
populations (1961), and Hildemann (1962) has pointed out the potential
usefulness of scale transplants in subpopulations analogous to those
conducted on amphibians ( Hildemann and Haas, 1961).
Ball and Kallman (1962) also report the success of whole pituitary
transplants into the tail musculature of adults of the all-female, gynogenetic teleost, Molliensiu formosa. This experiment is noted because
it is representative of the area of transplantation so well exploited,
especially in amphibians, by embryologists, and it is concerned with
discovering aspects of physiology other than those that are the subject
of this chapter.
IV. COMPLEMENT
Early immunologists soon discovered that the fresh normal serum
of humans and laboratory animals contained a system of molecules that
worked together to lyse red blood cells (and some bacteria) to which
specific antibodies were attached. The system has come to be called
“complement” (symbolized C’ ) . Some of its components are inactivated